Sughrue, Mion, Zinn, Macpeak, and Seas
5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof
 5-fluoro-2'-deoxyuridine derivatives expressed by general formula (1) and their pharmacologically permissible salts ##STR1## wherein A indicates a saturated or unsaturated divalent aliphatic hydrocarbon group having 1 to 30 carbon atoms; the letter n indicates 0 or 1, and when n is 0, it indicates that Y is directly bound to an oxygen atom; Y represents a hydrogen atom, phenyl group, or substituted phenyl group; however, when Y is a hydrogen atom, n is 1; R indicates a hydrogen atom or alcohol-protecting group. These compounds have a very strong antitumor activity. 
Teijin Limited
C Y
C07H Y02P
inventional additional
Masahiko Hisashi Yoshinori Takeshi Kenzo Takeo
Saito Fukushima Kato Hara Watanabe Oba