Wenderoth, Lind & Ponack
Aminoglycoside compounds, processes for production thereof, and pharamaceutical composition containing the same
 An aminoglycoside compound represented by the following formula (I) ##STR1## wherein one of R.sub.1 and R.sub.2 represents a hydrogen atom, and the other represents a methyl group, PA1 R.sub.3 represents a hydrogen atom or a hydroxyl group, PA1 R.sub.4 represents a hydrogen atom, a hydroxyl group or a methoxy group, PA1 n represents an integer of 1 to 5, PA1 W represents a divalent group of the formula --NHCO.fwdarw., --CONH.fwdarw., --COO.fwdarw., or --S.fwdarw. in which .fwdarw. represents a bond to X, and PA1 X represents (i) a single bond or (ii) a C.sub.1 -C.sub.20 trivalent acyclic saturated hydrocarbon group, and PA1 Y and Z are separately defined according to the cases (i) and (ii) above, and its pharmaceutically acceptable acid addition salt; and a process for producing the above aminoglycoside compound. A pharmaceutical composition comprising the above aminoglycoside compound is useful as an antibiotic. 
Kowa Company, Ltd.
A C Y
A61P C07H Y02P
inventional inventional additional
Isamu Kazuhiro Takahiro Toshihito
Watanabe Kamiya Torii Mori