Hamilton, Brook, Smith & Reynolds, P.C.
Diaminopropanol renin inhibitors
Described are diaminopropanols of which are orally active and bind to renin to inhibit its activity. They are useful in the treatment or amelioration of diseases associated with elevated. levels of renin activity or in the treatment of aspartic protease mediated disorders. Also described is a method for the use of the diaminopropanols in ameliorating or treating renin related disorders in a subject in need thereof.
Vitae Pharmaceuticals, Inc.
A A C C A C C A
A61P A61P C07D C07D A61P C07D C07D A61P
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Robert D. Colin M. David A. Zhenrong Patrick T. Jing Gerard Wei Suresh B. Alexey V. Lawrence W. John J. Salvacion
Simpson Tice Claremon Xu Flaherty Yuan McGeehan Zhao Singh Ishchenko Dillard Baldwin Cacatian