Roylance, Abrams, Berdo & Goodman, L.L.P.
Non-hemolytic ClyA for excretion of proteins
The disclosure below provides a protein export system utilizing non-hemolytic variants of HlyE family member proteins for efficiently producing recombinant protein from a host cell. In a preferred embodiment, the protein export system utilizes protein export machinery endogenous to the host bacterium into which the protein export system vector is introduced.
UNIVERSITY OF MARYLAND, BALTIMORE
C C A C
C07K C07K A61P C12N
inventional additional inventional inventional
James E. Yuansha
Galen Chen