Troutman Sanders LLP
Methods and compositions for inhibition of viral replication
The present invention is directed to methods and compositions that are effective in the inhibition of viral replication. In particular, the methods and compositions are effective at interfering with the activity of host cell proteins required in viral replication. For example, an embodiment of the invention is directed to inhibition of flavivirus replication wherein the replication is effected by changing the normal interactions of the host cell protein TIAR or TIA-1.
Georgia State University Foundation, Inc.
C C C A C Y C C G
C12Q C12N C12N A61K C12N Y02A C12N C12N G01N
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Wei Margo A.
Li Brinton