Fish & Richardson P.C.
Genetically modified non-human animal with human or chimeric PD-L1
This disclosure relates to genetically modified animal expressing human or chimeric (e.g., humanized) programmed death-ligand 1 (PD-L1, PDL1, or B7-H1), and methods of use thereof. In one aspect, the disclosure relates to genetically-modified, non-human animals whose genome comprises at least one chromosome comprising a sequence encoding a human or chimeric programmed death-ligand 1 (PD-L1).
Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
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Yuelei Chaoshe Rui Yanan Xiaofei Yang
Shen Guo Huang Guo Zhou Bai