Nelson Mullins Riley & Scarborough LLP
High concentration antibody formulations
The present disclosure relates to, inter alia, stable aqueous solutions comprising a high concentration of an antibody that binds to human complement component C5 and methods for preparing the solutions. The disclosure also provides methods for treating or preventing complement-associated disorders (for example, age-related macular degeneration or rheumatoid arthritis) using the solutions. Also featured are therapeutic kits containing one or more of the solutions and a means for administering the solutions to a patient in need such a treatment.
Alexion Pharmaceuticals, Inc.
C A A C C A A C A A A A C A A C A A A C A
C07K A61P A61K C07K C07K A61K A61K C07K A61K A61K A61K A61P C07K A61K A61K C07K A61K A61P A61K C07K A61P
additional inventional additional additional additional inventional additional additional inventional inventional additional inventional inventional additional inventional additional inventional inventional inventional additional inventional
Yi Xiao-Hong
Wang Zhou