Method of inhibiting C-KIT kinase
A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a compound of the present invention:or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof.The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.
Janssen Pharmaceutica NV
A A C A A C A A A C C C C A A C
A61N A61P C07D A61K A61N C07D A61K A61K A61K C07D C12N C07D C07D A61K A61K C07D
inventional inventional inventional inventional additional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Kenneth J. Sanath K. M. Jonathan Jinsheng Carl M. Christopher J. Shelley K. Mark J. Carl R. Renee Louise
Wilson Meegalla Rudolph Chen Manthey Molloy Ballentine Wall Illig Desjarlais