Barnes & Thornburg LLP
Method for preparing an N-cyclopropylmethyl aniline compound
Provided is a method for preparing an N-cyclopropylmethyl aniline compound, which comprises reacting a compound represented by Formula IV with cyclopropyl formaldehyde in the presence of metal zinc and an acid to generate an N-cyclopropylmethyl aniline compound represented by Formula I. The method of the present disclosure has mild reaction conditions, short reaction time, a high yield, simple processes, simple operations and low costs, and is more applicable to industrial production.
CHANG SHA JIA QIAO BIOTECH CO., LTD.
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Zheng Jintao Liangming Chaoqun Rong
Luo Zhu Luo Huang Zhang