Sterne, Kessler, Goldstein & Fox P.L.L.C.
Antibodies against human FZD5 and FZD8
Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided.
OncoMed Pharmaceuticals, Inc.
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Sanjeev H. Timothy Charles Austin L. Fumiko Takada Satyajit Sujit Kumar Aaron Ken
Satyal Hoey Gurney Axelrod Mitra Sato