Viksnins Harris & Padys PLLP
Heterocyclic inhibitors of MEK and methods of use
Disclosed are compounds of the Formulaand pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8, R9, W, and X are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
Array BioPharma Inc.
A A A A A A A A A A A C A A C A A C A C A C A A C C C C A C C A A A C A A A A A C A A C A C A A
A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C07D A61P A61P C07D A61P A61P C07D A61P C07D A61P C07D A61P A61P C07D C07D C07D C07D A61P C07D C07D A61P A61P A61P C07D A61P A61P A61P A61P A61P C07D A61P A61P C07D A61P C07D A61P A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Allison L. Jeongbeob Joseph P. James F. Eli M. Hong-Woon
Marlow Seo Lyssikatos Blake Wallace Yang