Foley & Lardner LLP
1,3-benzodioxole derivative
The present invention provides a compound having a particular chemical structure or a pharmacologically acceptable salt thereof which has an excellent inhibitory effect on EZH1 and/or EZH2 activity. The present invention provides a compound having a 1, 3-benzodioxole structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, or a pharmaceutical composition comprising the compound (wherein R1, R2, R3, R4, R5, R6, and V in the formula (I) are each as defined in the present specification).
DAIICHI SANKYO COMPANY, LIMITED
A C C A A C
A61P C07D C07D A61P A61P C07D
inventional inventional inventional inventional inventional inventional
Takao Yoshito Jun Keisuke Tomonori Nobuaki Akira Daisuke Osamu
Horiuchi Hamada Watanabe Suzuki Yamasaki Adachi Nakao Honma Kanno