Abelman, Frayne & Schwab
Activin receptor-like kinase-1 proteins having serine-threonine kinase domains
A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-beta-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
Ludwig Institute for Cancer Research
A C
A61K C07K
additional inventional
Peter Kohei Carl-Henrik Hidetoshi Petra
ten Dijke Miyazono Heldin Yamashita Franzen