Viksnins Harris & Padys PLLP
Substituted quinazolines as serine/threonine kinase inhibitors
Compounds having the formula (I) wherein R1, R2, R3 and Ar as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.
Array BioPharma Inc. Genentech, Inc.
A A C A C
A61P A61P C07D A61P C07D
inventional inventional inventional inventional inventional
David A. Peter J. Huifen Mark Joseph James F. Jason Eli M. John Lewis Christopher S. Samuel Robert J. Rustam Ferdinand Jacob
Moreno Mohr Chen Chicarelli Blake Demeese Wallace Gaudino Gazzard Siedem Kintz Kaus Garrey Schwarz