Riverside Law LLP
Composition for preventing or treating menopause, containing Lactobacillus intestinalis
The present invention relates to: a novel Lactobacillus intestinalis YT2 strain (deposition number: KCCM11812P); and a composition for preventing, alleviating, or treating menopause, comprising, as an active ingredient, Lactobacillus intestinalis comprising the novel strain. The present inventors have established an animal model for menopause through ovariectomy, confirmed changes of the distribution of intestinal microorganisms by the model, identified and isolated a novel Lactobacillus intestinalis strain among lactic acid bacteria of which the distribution is significantly reduced in the menopausal model, and confirmed effects, by means of the novel strain and previously reported Lactobacillus intestinalis strains, of alleviating menopausal symptoms, such as the inhibition of an increase in body fat, the inhibition of a decrease in bone mineral density, the inhibition of an increase in the pain sensitivity, and the alleviation of depression. Therefore, it is expected that the composition comprising the Lactobacillus intestinalis according to the present invention can be usable for a use of preventing, alleviating, or treating menopause.
KOREA FOOD RESEARCH INSTITUTE
C A A C A A A C A
C12N A23L A61K C12R A61Q A61P A61K C12N A61K
inventional inventional additional additional inventional inventional inventional inventional inventional
Eun-Yeong So-Young Hee Soon Jae-Goo Eun-Ji Young-Do Yun-Tai
Lim Lee Shin Kim Song Nam Kim