Lexyoume IP Meister, PLLC
Drug delivery system using hyaluronic acid-peptide conjugate micelle
The present invention relates to a drug delivery composition comprising a hyaluronic acid-peptide conjugate micelle and a production method thereof. According to the drug delivery composition and the production method of the drug-loaded, hyaluronic acid-peptide conjugate micelle of the present invention, the reaction for encapsulating can proceed in a mixed solvent of an aqueous solvent and an organic solvent. Therefore, the present invention can be applied to various types of water-insoluble active components and the biocompatible and biodegradable derivative can encapsulate a drug to provide a drug-loaded micelle, which is safe to be applied for human bodies. Moreover, the micelle has a therapeutic effect from the peptide contained therein, which can act in combination with the drug as packing therein. Therefore, the drug delivery composition and its production method can be utilized in the field of producing a sustained release formulation with an extended duration of the medicinal effect.
Postech Academy-Industry Foundation
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Y10S Y10S A61K A61K A61K A61P A61P A61K A61K A61K A61K A61P
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Yoon Keun You Me Hyemin Choun-Ki Kitae Jeong-A Sei Kwang Seung Kew Wonhee Ki Su Jun-Sub Eun Ju
Kim Tae Kim Joo Park Yang Hahn Yoon Hur Kim Choi Oh