Incyte Genomics, Inc.
Mammalian toxicological response markers
The present invention relates to mammalian nucleic acid and protein molecules comprising a plurality of nucleic acid and protein molecules. The mammalian nucleic acid molecules can be used as hybridizable array elements in a microarray in diagnostic and therapeutic applications including detecting metabolic and toxicological responses, and in monitoring drug mechanism of action. The protein molecules can be used in a pharmaceutical composition. The present invention also relates to methods for screening compounds and therapeutics for metabolic responses indicative of a toxic compound or molecule.
Incyte Genomics, Inc.
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C12Q A61P A61P A61P C12Q C12Q A61P
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Jeffrey J. Gary B. Preeti Matthew R. Henry Mariah R. Scott R. Mary Jane Yalda
Seilhamer Zweiger Lal Kaser Yue Baughn Panzer Cunningham Azimzai