Seed IP Law Group LLP
Risperidone sustained release microsphere composition
A risperidone sustained release microsphere formulation is provided. The microsphere formulation comprise risperidone or 9-hydroxy risperidone or salts thereof, and a polymer blend having a first uncapped lactide-glycolide copolymer and a second uncapped lactide-glycolide copolymer, in which the first uncapped lactide-glycolide copolymer is a copolymer with a high intrinsic viscosity and the second uncapped lactide-glycolide copolymer is a copolymer with a low intrinsic viscosity. The sustained release microsphere formulation according to an embodiment of the present disclosure is suitable for large-scale industrialized production with improved stability, the in vivo release behavior of which will not change after long-term storage.
Nanjing Luye Pharmaceutical Co., Ltd. Shandong Luye Pharmaceutical Co., Ltd.
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Wanhui Rongcai Kaoxiang Oilin Youxin Wenyan
Liu Liang Sun Wang Li Wang