Muirhead and Saturnelli, LLC
System and method for absolute quantitation of proteins
Absolute quantitation of protein in a sample is provided by comparing a sum or average of the N highest ionization intensities observed for peptides of a particular protein along with a calibration standard. The calibration standard can be in the form of a table generated by prior protein peptide analysis performed using one or more pre-determined proteins. The comparison is used to determine a corresponding absolute quantity of protein based on the observed sum or average of ionization intensities. A simple conversion factor can be applied to the calibration standard value to determine the absolute quantity of protein in the sample.
Waters Technologies Corporation
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inventional inventional
Guo-Zhong Jeffrey Cruz Scott Hans
Li Silva Geromanos Vissers