Chalker Flores, LLP
Method for preparing urate transporter 1 inhibitor
Provided is a method for preparing a URAT1 inhibitor, 2-((5-bromo-4-((4-bromonaphthalen-1-yl)methyl)-4H-1,2,4-triazol-3-yl)thio) acetic acid represented by the following formula ZXS-BR, the reaction equation of which being shown as follows. Compared with the prior art, the preparation method provided by the present application is of low cost, ease of handling, ease of quality control, and applicable to industrialization.
TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO., LTD.
C C A
C07D C07D A61P
inventional inventional inventional
Meixiang Haizhi Changying Lida Yuquan Wei Guilong Yafei Weiren Yuqiang Jingwei Huihui
Zou Zhang Liu Tang Li Liu Zhao Xie Xu Liu Wu Chen