Lucas & Mercanti, LLP
Human resistin receptor and use thereof
The present invention concerns a human resistin receptor. More particularly, the present invention provides a method for screening a receptor of human resistin protein, a method for preventing or treating an inflammatory disease and arteriosclerosis using an expression- or activity-regulator for a human resistin receptor, and a pharmaceutical composition including an expression- or activity-regulator for the human resistin receptor. The method for screening a human resistin protein receptor according to the present invention enables separation of a receptor which directly binds to resistin from human monocyte, reveals a mechanism of signal transduction of the resistin receptor, and therefore, is expected to contribute to regulation of an inflammatory effect of monocyte, molecular detection of causes for vascular inflammation and arteriosclerosis, and developments of prevention and a treating agent for an inflammatory disease and arteriosclerosis.
Seoul National University Hospital
G G G
G01N G01N G01N
inventional inventional additional
Sahmin Yoo Wook Young Jin Jun Ho Hyun Chae Sang Eun Young Bae Hyo Soo
Lee Kwon Cho Chung Lee Lee Park Kim