McCarter & English, LLP
Triazole compounds that modulate Hsp90 activity
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Synta Pharmaceuticals Corp.
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Dinesh U. Teresa Junghyun James Elena Chi-Wan Shijie Howard P. Kevin Weiwen Zhenjian David
Chimmanamada Przewloka Chae Barsoum Kostik Lee Zhang Ng Foley Ying Du James