Pyrazolones as inhibitors of 11β-hydroxysteroid dehydrogenase
Provided herein are compounds of the formula (I):as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
Hoffmann-La Roche Inc.
A A A C A A
A61P A61P A61P C07D A61P A61P
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Agnieszka Robert Alan Kshitij Chhabilbhai Jefferson Wright Nathan Robert Nancy-Ellen Bruce Lester Sherrie Lynn Kevin Richard Alexander Joseph Anthony Nader Matthew Michael Paul Michael Paul
Kowalczyk Goodnow, Jr. Thakkar Tilley Scott Haynes Banner Pietranico-Cole Guertin Mayweg Bilotta Fotouhi Hamilton Gillespie Myers