Edwards & Angell, LLP
Dermal scaffold using alkaline pre-treated chitosan matrix or alkaline pre-treated chitosan and alkaline pre-treated collagen mixed matrix
Disclosed are a dermal scaffold comprising alkaline pre-treated free amine-containing chitosan matrix, alkaline pre-treated free amine-containing chitosan and alkaline pre-treated collagen mixed matrix, or alkaline pre-treated free amine-containing chitosan and alkaline pre-treated collagen mixed matrix containing chitosan fabrics, which has excellent wound healing effect by constituting microenvironments suitable for migration and proliferation of fibroblasts and vascular cells surrounding the wound to be extremely useful as wound healing dressings, and a bioartificial dermis comprising the dermal scaffold and human fibroblasts, particularly useful for healing broad wound sites such as burns.
Korea Atomic Energy Research Institute
A A C A A C C C A A
A61L A61L C12N A61L A61K C12N C12N C12N A61L A61L
inventional inventional inventional inventional additional additional additional inventional inventional inventional
Yong-Ha Young-Sook Seung-Hoon Chun-Ho Yong-Jae Kyu-Bo Seok-Il
Youn Son Lee Kim Gin Han Hong