Womble Bond Dickinson (US) LLP
Three-dimensional representation of skin structure
The present disclosure generally relates to an automated method and system for generating a three-dimensional (3D) representation of a skin structure of a subject. The method comprises: acquiring a plurality of two-dimensional (2D) cross-sectional images of the skin structure, specifically, using optical coherence tomography (OCT) technique; computing a cost for each 2D cross-sectional image based on a cost function, the cost function comprising an edge-based parameter and a non-edge-based parameter; constructing a 3D graph from the 2D cross-sectional images; and determining a minimum-cost closed set from the 3D graph based on the computed costs for the 2D cross-sectional images, wherein the 3D representation of the skin structure is generated from the minimum-cost closed set.
Agency for Science, Technology and Research National Skin Centre (Singapore) PTE LTD
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Jiang Hong Liang Ai Ping Carolin Jun Annan Wing Kee Damon Ruchir
Liu Tey Yow Wall Cheng Li Wong Srivastava