Brinks Hofer Gilson & Lione
Secreted and transmembrane polypeptides and nucleic acids encoding the same
The present invention is directed to nucleic acids encoding a secreted polypeptide that inhibits neoplastic growth in tumor cells. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Genentech, Inc.
A C
A61K C07K
inventional inventional
J. Christopher David William I. Austin L. Margaret Ann Paul J. Audrey
Grimaldi Botstein Wood Gurney Roy Godowski Goddard