Oxazolidinone antibacterial agent with tricyclic substituents
 This invention provides novel oxazolidinone derivatives represented by chemical Formula (I), or pharmaceutically acceptable salts thereof: ##STR1## wherein X is NR.sub.1, CR.sub.2 R.sub.3, O, S, SO, or SO.sub.2 ; and Z is NR.sub.4, S, SO, SO.sub.2 or O. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci and streptococci, as well as anaerobic organisms such as bacteroides and clostridia species, and acid-fast organisms such as Mycobacterium tuberculosis and Mycobacterium avium. 
Pharmacia & Upjohn Company
A A C
A61P A61P C07D
inventional inventional inventional
Douglas K. Hiroyoshi Gary J. Richard C.
Hutchinson Yamada Cleek Thomas