DLA Piper LLP (US)
Biodegradable particle, vascular embolization material and method for producing biodegradable particles
A biodegradable particle including a block copolymer produced by copolymerization of a biodegradable copolymer having a structure composed of hydroxycarboxylic acid a1, whose homopolymer produced by homopolymerization has a glass transition point of not less than 40° C., and hydroxycarboxylic acid a2, whose homopolymer produced by homopolymerization has a glass transition point of not more than −40° C.; a water-soluble polymer comprising a functional group selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group at each of both ends; and a polyvalent compound comprising 2 or more functional groups each selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group; wherein a ratio of mass of said structure composed of hydroxycarboxylic acid a2 to mass of said biodegradable copolymer is 30 to 90% by mass.
Toray Industries, Inc.
C A C A A A A C C C
C08G A61L C08G A61L A61L A61L A61L C08J C08J C08G
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Kazuhiro Masaki Yoshitake Megumi Yasufumi
Tanahashi Fujita Takahashi Nakanishi Yamamura