Process for making 5-azacytosine nucleosides and their derivatives
A process of synthesizing a 5-azacytosine nucleoside, such as azacitidine and decitabine, comprises coupling a silylated 5-azacytosine with a protected D-ribofuranose of formula in the presence of a sulfonic acid catalyst.
ScinoPharm Taiwan, Ltd.
C A C C A
C07H A61P C07H C07H A61P
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Yung Fa Xiaoheng Julian Paul Lunghu
Chen Zhang Henschke Wang