Ice Miller LLP
Fusion protein comprising a ligand binding domain of VEGF and PDGF
Fusion proteins containing a PDGF binding portion, a VEGF binding portion, and an Fc antibody region are described. Also described are nucleic acids encoding the fusion proteins, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing clinical conditions characterized by abnormal angiogenesis, such as vascular permeability, edema or inflammation.
AP Biosciences Inc. Allgenesis Biotherapeutics Inc.
A A C C A C A
A61P A61P C07K C07K A61K C07K A61P
inventional inventional additional additional additional inventional inventional
Pei-Tzu Ching-Hsuan Jiun-Shyang Kevin Jeng-Horng Huang-Tsu
Wu Hsu Leou Zen Her Chen