New England Biolabs, Inc.
High fidelity restriction endonucleases
Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.
New England Biolabs, Inc.
C C C C C G C G
C12Q C12Q C12Y C12N C12Q G01N C12N G01N
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Siu-hong Chunhua Aine Zhenyu Yishu Dapeng Shengxi Shuang-Yong Xianghui Xuhui
Chan Zhang Quimby Zhu Huang Sun Guan Xu Li Lai