Fish & Neave
Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of making and using them
This invention relates to compositions comprising highly fluorinated, chloro-substituted, non-cyclic organic compounds having 7 to 9 carbon atoms and to processes of making and using them. More particularly, this invention relates to emulsions comprising those highly fluorinated, chloro-substituted organic compounds. This invention also related to emulsion comprising noncyclic perfluorochlorethers having 7 to 10 carbon atoms, preferably 7 to 9 carbon atoms. These novel emulsions have various medical and oxygen transport applications. They are especially useful medically as contrast media, for various biological imaging modalities such as nuclear magnetic resonance, ultrasound, x-ray, computed tomography, .sup.19 F-magnetic resonance imaging, and position emission tomography, as oxygen transport agents or "artificial bloods," in the treatment of heart attack, stroke, and other vascular obstructions, as adjuvants to coronary angioplasty and in cancer radiation treatment and chemotherapy.
Minnesota Mining & Manufacturing Co. HemaGen/PFC
A A C C A A A C A A A
A61K A01N C07C C07C A01N A61K A61K C07C A61K A01N A61K
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Richard M. George G. I. Thomas J. Robert J.
Flynn Moore Richard Kaufman