Alston & Bird, LLP
Liposomes comprising a calcium phosphate-containing precipitate
Provided herein are methods and compositions for the delivery of bioactive compounds to a cell, tissue, or physiological site. The compositions comprise delivery system complexes comprising liposomes encapsulating a biodegradable ionic precipitate having incorporated therein a bioactive compound and delivery system complexes comprising a biodegradable ionic precipitate ionically bound to a surrounding lipid bilayer, wherein the biodegradable ionic precipitate comprises a bioactive compound. Also provided herein are methods for the treatment of a disease or an unwanted condition in a subject, wherein the methods comprise administering the delivery system complexes comprising bioactive compounds that have therapeutic activity against the disease or unwanted condition to the subject.
The University of North Carolina at Chapel Hill
A C C A A A A A A A A A A A A A C A A A A A A A A A A A A A A C A
A61K C12N C12N A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C12N A61P A61K A61K A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C12N A61P
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Jun Leaf
Li Huang