Fluorinated pyridine N-oxide thrombin modulators and process for N-oxidation of nitrogen containing heteroaryls
The present invention describes compounds of Formula Ior a pharmaceutically acceptable salt thereof, for the prophylaxis, or treatment of diseases and conditions related to thrombin activity in a mammal. The present invention also relates to a novel method of N-oxidation of nitrogen containing heteroaryls.
Janssen Pharmaceutica N.V.
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Christopher Kevin Tianbao Xizhen Yu Kai Mark
Teleha Kreutter Lu Zhu Lee Player