McCarter & English, LLP
Triazole compounds that modulate HSP90 activity
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a pharmaceutical composition comprising such a compound.
Synta Pharmaceuticals Corp.
C A A A C C Y C A A C C A C C C A A A C C A A A C A C C C A C C A C
C07D A61P A61P A61P C07D C07D Y02A C07D A61P A61K C07D C07D A61K C07D C07D C07D A61P A61P A61K C07D C07D A61K A61P A61K C07D A61K C07D C07D C07D A61K C07D C07D A61K C07D
inventional inventional inventional inventional inventional inventional additional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Dinesh U. Shijie Weiwen Joseph Minghu Junghyun Stefan M.
Chimmanamada Zhang Ying Burlison Song Chae Schweizer