Lerner, David, Littenberg, Krumholz & Mentlik, LLP
Method for preparing polyethylene glycol dialdehyde derivative
The present invention relates to an improved method for preparing a high purity polyethylene glycol dialdehyde derivative. The preparation method can provide the polyethylene glycol dialdehyde derivative suitable as a raw material for pharmaceuticals because of high purity and terminal activity, by using PEG-diacetal, which is prepared by reacting polyethyleneglycol methanesulfonate with dialkoxy-1-propanol, as an intermediate.
Hanmi Fine Chemical Co., Ltd.
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Jun Ho Bo Sung Eun Rang Yu Rim Young Bum
Chu Kwon Park Kim Cho