Sughrue Mion, PLLC
Antibodies against HMB1, and composition comprising same for treating or preventing alzheimer's disease
An anti-HMGB1 antibody comprising a light chain variable region comprising complementarity-determining regions or the like including amino acid sequences of SEQ ID NOs: 4 to 6, and a heavy chain variable region comprising complementarity-determining regions or the like including amino acid sequences of SEQ ID NOs: 10 to 12, or an anti-HMGB1 antibody comprising a light chain variable region or the like comprising an amino acid sequence of SEQ ID NO: 3, and a heavy chain variable region comprising an amino acid sequence or the like of SEQ ID NO: 9, and a composition for treating or preventing Alzheimer's disease, comprising the same as an active ingredient.
National University Corporation Tokyo Medical and Dental University
A C A A C C C C C C
A61P C07K A61K A61K C12N C07K C12N C12N C07K C07K
inventional inventional additional inventional inventional inventional inventional inventional additional additional
Masunori Hitoshi
Kajikawa Okazawa