Aminopyrimidine derivatives as LRRK2 inhibitors
Compounds of the formula I:or pharmaceutically acceptable salts thereof,wherein m, n. X, R1, R2, R3, R5, R6 and R7 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease.
Genentech, Inc.
A C A C C C C A C
A61P C07D A61P C07D C07D C07D C07D A61P C07D
inventional inventional inventional inventional inventional inventional inventional inventional inventional
Huifen Zachary Anthony Charles Janet Guiling Mark Daniel Daniel Jon Bryan K. Shumei
Chen Sweeney Estrada Baker-Glenn Gunzner-Toste Zhao Chambers Shore Burdick Chan Wang