Sterne, Kessler, Goldstein & Fox P.L.L.C.
Methods of use for an antibody against human frizzled receptors 1, 2. 5, 7 or 8
Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided.
OncoMed Pharmaceuticals, Inc.
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Satyajit Sujit Kumar Sanjeev H. Austin L. Timothy Charles Aaron Ken Fumiko Takada
Mitra Satyal Gurney Hoey Sato Axelrod