Antibodies against PD-1 and uses thereof
The present invention provides antibodies and antigen-binding fragments that specifically bind PD-1 (Programmed Death 1), thereby modulating immune responses in general, and those mediated by TcR and CD28, in particular. The disclosed compositions and methods may be used for example, in treating autoimmune diseases, inflammatory disorders, allergies, transplant rejection, cancer and other immune system disorders.
MedImmune Limited
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Mathieu Ross Andrew G.
Chodorge Stewart Buchanan