Hunton & Williams LLP
Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste
Binding assays for identifying compounds that induce or modulate the T1R1/T1R3 (umami) receptor-associated taste are provided. These binding assays detect the specific binding of a compound to a T1R1/T1R3 (umami) taste receptor or detect the modulation (inhibition or enhancement) of the binding of another compound, e.g., L-glutamate, L-aspartate or lactisole to a T1R1/T1R3 umami taste receptor. Compounds that are identified in these binding assays have potential application as T1R1/T1R3 umami taste modulators and therefore can be used as flavor additives in compositions for human or animal consumption.
Senomyx, Inc.
A G C
A01K G01N C07K
additional additional inventional
Shawn Fernando Hong Jon Elliot Xiaodong Lena Sergey Mark
O'Connell Echeverri Xu Adler Li Staszewski Zozulya Zoller