Christie, Parker & Hale, LLP
Method to remove citrate and aluminum from proteins
A method is provided for removing citrate, aluminum, and other multivalent ions and contaminants from proteins by adjusting the pH of a solution containing the protein to a pH from about 7 to about 10, and diafiltering the pH-adjusted solution against aqueous solutions which have a low level of ions.
Alpha Therapeutic Corporation
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C07K A61M A61M A61M A61M A61M
inventional additional additional additional inventional additional
Leticia R. Raja R. Takashi Mauro C. Hirokazu
Regis Mamidi Goto Mojica Ito