Cooley LLP
Salt form of a human histone methyltransferase EZH2 inhibitor
Provided herein is N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4′-(morpholinomethyl)-[1,1′-biphenyl]-3-carboxamide hydrobromide. Also provided herein is a particular polymorph form of this compound.
Epizyme, Inc. Eisai R&D Management Co., LTD.
Y C C A A
Y02A C07D C07D A61P A61K
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Arani Kuan-Chun Kevin Wayne Steven Hyeong Wook Kristen Frances
Chanda Huang Kuntz Mathieu Choi Sanders Fang