Substituted pyrazoles and uses thereof
The present invention provides for compounds of formula 0 and various embodiments thereof, and compositions comprising compounds of formula 0 and various embodiments thereof.In compounds of formula 0, the groups R1A, R1B, R1C, R1D, R2, R3, R4, R5 and R6 have the meaning as described herein. The present invention also provides for methods of using compounds of formula 0 and compositions comprising compounds of formula 0 as DLK inhibitors and for treating neurodegeneration diseases and disorders.
Genentech, Inc.
C C C C C C C C C C A C
C07D C07D C07D C07D C07D C07D C07D C07D C07D C07D A61P C07D
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Snahel Joseph P. Guibai Michael Anthony Kevin Wen
Patel Lyssikatos Liang Siu Estrada Chen Liu