Buchanan Ingersoll & Rooney PC
Crystalline FGFR4 inhibitor compound and uses thereof
A number of crystalline forms of N-(2-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-yl)phenyl)acrylamide are provided. These include a crystalline free base form, a crystalline monohydrochloride salt form, a crystalline dihydrochloride salt form, and a crystalline ethanesulfonate salt form. Methods of making and using crystalline compounds are also provided.
Eisai R&D Management Co., LTD.
A C C A A A
A61P C07D C07D A61K A61P A61P
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Kenshi George Kristen Arani
Yoshida Moniz Sanders Chanda