McDonnell Boehnen Hulbert & Berghoff LLP
Pyrimidinones as casein kinase II (CK2) modulators
A compound having Formula I: or a pharmaceutically acceptable salt thereof, wherein X, R, R and R are as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof. The compounds of Formula I are inhibitors of Casein kinase II (CK2) pathways.
Exelixis, Inc.
A C C A C C
A61P C07D C07D A61P C07D C07D
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Amy L. Wai Ki Vicky Elena S. Hongwang Cristiana A. Wei Michael Moon Hwan Peiwen Ping Arlyn Patrick Jeffry Kimo Naing Brian
Tsuhako Chan Koltun Du Zaharia Xu Pack Kim Zhou Huang Arcalas Kearney Curtis Aay Kane