Myers Bigel Sibley & Sajovec, PA
Eponemycin and epoxomicin analogs and uses thereof
The present invention provides compounds having formula (1): wherein R1-R6, A, J, D, E, G, Q, w, x, y, and z are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of cancer and/or inflammatory disorders, and more generally as proteasome inhibitors.
Eisai R&D Management Co., Ltd.
A C A C C A A C C C A C A A
A61P C07F A61P C07F C07D A61P A61K C07D C07D C07D A61P C07K A61P A61P
inventional inventional inventional inventional inventional inventional additional inventional inventional inventional inventional inventional inventional inventional
Erin A. Shawn Charles Pamela Lynn Sergei Mary Kozo Xiang-Yi Yimin Frank Jiayi Jean-Christophe
Murphy Schiller Johannes McGuiness Hawkins Agoulnik Vermeulen Akasaka Li Jiang Fang Wu Harmange