Abelman, Frayne & Schwab
Antibodies which bind specifically to activin receptor like kinase 3
A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-β-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
Ludwig Institute for Cancer Research
C A
C07K A61K
inventional additional
Petra Kohei Peter Carl-Henrik Hidetoshi
Franzen Miyazono ten Dijke Heldin Yamashita