Anderson Kill & Olick, P.C.
Arteminolide derivatives and process for the manufacture thereof
 Arteminolides obtained from Artemisia sylvatica MAXIMOWICZ and having a core structure of formula (I) or an isomeric structure thereof are effective farnesyl-protein transferase inhibitors as well as angiogenesis suppressors, and, accordingly, they are useful for the treatment of various cancers and angiogenesis-related diseases. ##STR1## 
Korea Institute of Science and Technology
C
C07D
inventional
Song-Hae Jongheon Byoung-Mog Mi-Jeong Youngwan Soo-Ik Seung-Ho Young-Kook
Bok Shin Kwon Kim Seo Chang Lee Kim