Nixon & Vanderhye, PC
MiRNA markers for the diagnosis of osteosarcoma
The present invention discloses the use of miR-4714, miR-4521, and miR-1292 as diagnostic markers for osteosarcoma. High-throughput sequencing and QPCR experiments prove that the levels of miR-4714, miR-4521, and miR-1292 in the blood of normal and osteosarcoma patients are significantly different, and therefore miR-4714, miR-4521, and miR-1292 can be used as a molecular marker for the diagnosis of osteosarcoma for developing products for the diagnosis of osteosarcoma. The diagnostic product has the following advantages: non-invasive, rapid, sensitive, and has broad application prospects in clinical practice.
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inventional inventional additional additional
Xiaojuan Yihao Ya Su Dongqi Huiling Zhaoxin Junfeng Yanjin Zuozhang
Li Yang Zhang Li Li Li Zhang Xia Chen Yang