The Webb Law Firm
Radioactive arsenic-containing compounds and their uses in the treatment of tumors
This invention provides a process for producing a radioactive arsenic-containing compound, comprising the steps of: (i) subjecting an arsenic-containing compound to a neutron irradiation treatment, said arsenic-containing compound being selected from a group consisting of As2O3, As2S3, As2S2, and a combination thereof, such that the arsenic element contained in the arsenic-containing compound is converted to a radioactive arsenic isotope; and (ii) recovering the resultant product from step (i).This invention also provides a pharmaceutical composition comprising a therapeutically effective amount of the radioactive arsenic-containing compound and a pharmaceutically acceptable carrier. The pharmaceutical composition can be used in the treatment of tumors/cancers such as hematological malignancies and solid tumors.
Institute of Nuclear Energy Research Rocaec TTY Biopharm Company, Limited
A A A A A
A61P A61K A61P A61K A61K
inventional inventional inventional inventional inventional
Yin-Mao Kwo-Ping Te-Jung Kuo-Hsien Shyh-Yi Shiang-Rong Ying-Kai Charng-Feng Chun-Ying Ming-Shiuan Te-Wei Chih-Hsien Wei-Chuan
Hsu Chang Chen Fan Chyi Chang Fu Kao Huang Wu Lee Chang Hsu