Hunton & Williams LLP
T1R taste receptors and genes encoding same
Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in taste signaling, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for representing taste perception of a particular taste stimulus in a mammal are also described, as are methods for generating novel molecules or combinations of molecules that elicit a predetermined taste perception in a mammal, and methods for simulating one or more tastes. Further, methods for stimulating or blocking taste perception in a mammal are also disclosed.
Senomyx, Inc.
C G C C G G C G G
C07K G01N C12Q C07K G01N G01N C07K G01N G16B
inventional inventional inventional inventional additional inventional additional inventional inventional
Shawn Jon Elliot Lena Xiaodong Sergey
O'Connell Adler Staszewski Li Zozulya