Edwards Angell Palmer & Dodge LLP
Pyrimidine derivatives for treatment of hyperproliferative disorders
Pyrimidine derivatives of formula (I)in which J and Y represent aromatic or heteroaromatic rings; R2, G, G′, and G″ represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
Bayer Healthcare LLC
C C A C C A C C C A A C C C A C
C07D C07D A61P C07D C07D A61P C04B C07D C07D A61P A61P C07D C07D C07D A61P C07D
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Alexander Lei Manoj Chunguang Donald Lin Ann-Marie Jianqing Ming Michael Dhanapalan Julie A. Brian R. Yuanwei Wenlang Martin F.
Hillisch Zhang Patel Wang Bierer Yi Bullion Chen Wang Brands Nagarathnam Dixon Bear Chen Fu Hentemann