Nixon & Vanderhye P.C.
Process for isolation of anticancer agent camptothecin from Nothapodytes foetida
The present invention relates to an improved and economical process for the isolation of anticancer agent Camptothecin from the twigs and stem of Nothapodytes foetida using hot extraction 20(S) Camptothecin is an alkaloid, which contains a pentacyclic ring system that includes a pyrrolo [3,4-b] quinoline moiety (ring A, B and C), the pyridone ring D and a chiral center at C-20 in ring E.
Council of Scientific and Industrial Research
C
C07D
inventional
Santosh Kumar Merajuddin Suman Preet Singh
Srivastava Khan Khanuja