Chemokine-like factors (CKLFs) with chemotactic and hematopoietic stimulating activities
The present invention provides chemokine-like factor (CKLF) polypeptides with chemotactic and hematopoietic stimulating activities and polynucleotides encoding such polypeptides. Additionally, a method for producing such CKLF polypeptides by recombinant techniques is provided. Also provided are the antibodies and antagonists against such polypeptides. The present invention further disclose a drug compound comprising a therapeutically effective amount of such CKLF polypeptides as well as pharmaceutically acceptable excipients and carriers. Also disclosed are the uses of such CKLF polypeptides and polynucleotides in diagnostics or therapeutics to treat immunodeficiency, hematopoietic diseases and primary tumors.
Beijing Medical University Beijing Medical University United Biological Engineering Company
A C
A61K C07K
additional inventional
Dalong Guanghui Wenling Chunhui Jian Yingme Jiaqiang Quansheng
Ma Chen Han Di Tang Zhang Huang Song