Ballard Spahr Andrews & Ingersoll, LLP
hGC-1, a gene encoding a member of the olfactomedin-related protein family
An isolated acid having the sequence of a) SEQ ID NO: 1; b) the sequence of SEQ ID NO: 2; c) the sequence of SEQ ID NO: 3; d) a sequence complementary to any of a), b), or c); or e) a sequence of at least 10 contiguous nucleotides specific for any of a)-d). The invention relates to the identification and characterization of a hitherto unidentified human gene, hGC-1. The protein encoded by hGC-1 appears to be a member of the olfactomedin-related proteins. The invention relates generally to the gene (hGC-1), nucleic acids, cDNA, vectors, polypeptides, protein, antibodies, cells, transgenic animal, and other compositions related to hGC-1. Additionally, primers are provided for identifying hGC-1. The invention further relates to methods of using these compositions, such as diagnosis and treatment of various cancers, and kits comprising these compositions.
The United States of America as represented by the Secretary of the Department of Health and Human Services
A C C C
A61K C12Q C07K C12Q
additional inventional inventional additional
Griffin P. Jiachang Wen-li
Rodgers Zhang Liu