Swanson & Bratschun, L.L.C.
Escherichia coli containing mutated lpdA gene and application thereof
The invention relates to the field of modifying E. coli through genetic engineering. Specifically, the invention provides an E. coli containing a mutated lpdA gene. The invention also relates to use of the E. coli in the production of chemical material such as ethanol, and succinate etc. The invention also provides a method of producing chemical materials such as ethanol and succinate etc. by using the E. coli, as well as a method for increasing the activity of pyruvate dehydrogenase in E. coli by introducing a mutated lpdA gene.
TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES
C C C C C Y
C12P C12P C12P C12N C12N Y02E
inventional inventional inventional inventional inventional additional
Jing Xueli Xinna
Chen Zhang Zhu