Pyrazole compounds for treatment of neurodegenerative disorders
The invention provides compounds of Formula I:wherein R1, R2, R3, R4, R6, R7, R8, and A are as defined. Compounds of formula I have activity inhibiting production of Aβ-peptide. The invention also provides pharmaceutical compositions and methods for treating diseases, for example Alzheimer's disease, in mammals comprising compounds of Formula I.
Pfizer Inc
C C C C C A A C A C C C A C
C07D C07D C07D C07D C07D A61P A61P C07D A61P C07D C07D C07D A61P C07D
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Robert L. Martin P. Spiros Yuhpyng L.
Rosati Allen Liras Chen