Modulators of ATP-binding cassette transporters
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including CF Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Vertex Pharmaceutical Incorporated
A A A A A A A A G A C A A A A A A A A A A C A A A A C A A A A A A A C C C C A
A61P A61K A61P A61P A61P A61P A61K A61P G01N A61P C07D A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C07D A61P A61P A61K A61P C07D A61P A61P A61K A61P A61P A61P A61P C07D C07D C07D C07D A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Thomas Sara S. Mark T. Matthew Peter D. J. Ashvani K. Lewis R.
Cleveland Hadida Ruah Miller Hamilton Grootenhuis Singh Makings