4-Pyrimidone compounds
 The compounds are substituted isocytosines which are histamine H.sub.2 -antagonists. Two specific compounds of the present invention are 2-2-(5-methyl-4-imidazolylmethylthio)-ethylamino!-5-(3-methoxybenzyl)-4-p yrimidone and 2-2-(5-methyl-4-imidazolylmethylthio)ethylamino!-5-benzyloxy-4-pyrimidone . 
Smith Kline & French Laboratories Limited
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Thomas H. Charon R. John C. Graham J.
Brown Ganellin Emmett Durant