4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as MEK inhibitors
Phenylamino benzhydroxamic acid derivatives of the formulawhere R1, R2, R3, R4, R5, and R6 are hydrogen or substituent groups such as alkyl, and where R7 is hydrogen or an organic radical, are potent inhibitors of MEK and, as such, are effective in treating cancer and other proliferative diseases such as psoriasis and restenosis.
Warner-Lambert Company
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David Thomas Alan Robert Stephen Douglas Haile Alexander James Annette Marian
Dudley Saltiel Barrett Tecle Bridges Doherty