Knobbe, Martens, Olson & Bear, LLP
Administration of vaso-active agent and therapeutic agent
 A vaso-active agent is administered in combination with a therapeutic agent which is useful in treatment of tissue of the body which is located below the stratum corneum or the outermost layer of the epidermis, wherein the vaso-active agent may be administered by a local, topical or transdermal route to a particular site and the therapeutic agent may be administered in a similar manner in combination with the vaso-active agent or may be administered separately, wherein the vaso-active agent and the therapeutic agent for topical and/or transdermal administration may be provided in the form of a composition so as to increase local perfusion and/or concentration of the therapeutic agent at or adjacent an administration site of the vaso-active agent. 
The University of Queensland
A
A61K
inventional
Sheree Elizabeth Parminder Michael Stephen
Cross Singh Roberts