Townsend and Townsend and Crew LLP
Stable pharmaceutical composition for oral use
The present invention is to provide a stable pharmaceutical composition for oral use and preparation thereof in which changes are prevented in drug release at stored even under the exposure to light by adding yellow ferric oxide and/or red ferric oxide in a matrix type sustained-release preparation containing a drug, hydrophilic base, and polyethylene oxide. The present invention is to further provide a method for preventing changes in drug release at stored under the exposure to light in a matrix type sustained-release preparation containing a drug, hydrophilic base, and polyethylene oxide. The quality assurance period of the product can be prolonged and the product value can be improved by the present invention.
Yamanouchi Pharmaceuticals, Co., Ltd.
A A
A61K A61K
inventional inventional
Toyohiro Keiichi Tatsunobu Shunsuke Kazuhiro
Sawada Yoshihara Yoshioka Watanabe Sako