Irell & Manella
Derivatives of porphyrin useful in photodynamic therapy
Compounds which are long wavelength-absorbing derivatives of porphyrinone nuclei are described which are useful in photodynamic therapy and related technologies. These compounds contain the porphyrin nucleus beta-substituted with alkyl and/or omega-carboxyalkyl substituents wherein the ring system contains at least one exocyclic double bond in which the exocyclic participant is selected from the group consisting of .dbd.S, .dbd.CR'.sub.2, and NR".
Board of Trustees, a Constitutional Corporation Operating Michigan State University
A C A
A61K C07D A61K
inventional inventional inventional
Chi-Kwong Weishih
Chang Wu