Birch, Stewart, Kolasch & Birch, LLP
Brain activity analyzing apparatus, brain activity analyzing method and biomarker apparatus
Provided is a method of analyzing brain activities for realizing a biomarker for neurological/mental disorder, based on brain function imaging. From measured data of resting-state functional connectivity MRI of a healthy group and a patient group, correlation matrix (80) of degree of brain activities among prescribed brain regions is derived for each subject. Feature extraction is executed by regularized canonical correlation analysis (82) on the correlation matrix (80) and attributes of the subject including a disease/healthy label of the subject. Based on the result of regularized canonical correlation analysis, by discriminant analysis (86) through sparse logistic regression, a discriminator (88) is generated.
ADVANCED TELECOMMUNICATIONS RESEARCH INSTITUTE INTERNATIONAL
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Kazuhisa Yuka Mitsuo Kiyoto Takeo Ryuichiro Jun Nobumasa Noriaki
Shibata Sasaki Kawato Kasai Watanabe Hashimoto Morimoto Kato Yahata