Jones Day
Chimeric antigen receptors based on single domain antibodies and methods of use thereof
The present application provides single-domain antibodies, and chimeric antigen receptors comprising one or more antigen binding domains each comprising a single-domain antibody. Further provided are engineered immune effector cells (such as T cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating cancer are also provided.
Legend Biotech USA Inc.
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Pingyan Lei Lin Xiaohu Jiaying Chuan-Chu Qiuchuan
Wang Yang Wang Fan Hao Chou Zhuang