Cooper Legal Group, LLC
Antimicrobial peptide Sparamosin from Scylla paramamosain and application thereof
Provided is an antimicrobial peptide Sparamosin from Scylla paramamosain. The Sparamosin mature peptide and its functional domain Sparamosin26-54 were synthesized by solid-phase synthesis with a purity of over 95%. Both Sparamosin and Sparamosin26-54 exhibit strong antimicrobial activity. More importantly, Sparamosin26-54 has strong antifungal activity and could inhibit the growth of a variety of yeasts and filamentous fungi. Based on the potent antimicrobial activities of Sparamosin and Sparamosin26-54, both peptides could be developed as alternatives for conventional antibiotics, antimicrobial agents, feed additives in aquaculture and livestock, preservatives, and mold inhibitors.
Xiamen University
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C07K A23K A23K A61P A23K A61P C07K A61K A61K
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Kejian Hui Huiyun Ying Yanchao Fangyi
Wang Peng Chen Yang Chen Chen