Schwegman Lundberg & Woessner, P.A.
Anti-PD-L1 antibody for detecting PD-L1
The present invention provides an anti-PD-L1 antibody capable of staining tumor cells such as melanoma cells.An anti-PD-L1 antibody comprising (a) a light chain comprising CDR1 having the amino acid sequence of KSISKY (SEQ ID NO: 1), CDR2 having the amino acid sequence of SGS and CDR3 having the amino acid sequence of QQHNEYPLT (SEQ ID NO: 2) and (b) a heavy chain comprising CDR1 having the amino acid sequence of GYTFTDYI (SEQ ID NO: 3), CDR2 having the amino acid sequence of INPDSGGN (SEQ ID NO: 4) and CDR3 having the amino acid sequence of ARGITMMVVISHWKFDF (SEQ ID NO: 5). A composition for detecting PD-L1, comprising the above antibody as an active ingredient. A method for preparing the above antibody is also provided.
National University Corporation Hokkaido University Fuso Pharmaceutical Industries, Ltd.
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G01N G01N C07K C12N C12Q C07K C07K G01N C12N G01N C07K
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Kazuhiko Yumiko Yasuhiko Satoru Naoya Satoshi Asami Chie Tomohiro Shiro
Ohashi Kagawa Suzuki Konnai Maekawa Takagi Nishimori Nakajima Okagawa Murata