Gavrilovich, Dodd & Lindsey LLP
Composition for preventing or treating neurological disorder comprising aucubin
The present invention relates to a composition for preventing or treating a neurological disorder, comprising aucubin. Specifically, the present invention relates to a pharmaceutical composition for preventing or treating mental illness, comprising aucubin or a pharmaceutically acceptable salt thereof as an active ingredient, to a food composition, to a method for treating mental illness, and to a composition for maintaining the survival of GABAergic neurons, promoting the regeneration of GABAergic neurons, or preventing the apoptosis of GABAergic neurons.The aucubin according to the present invention exhibits effects of maintaining the survival of GABAergic neurons, promoting the regeneration of GABAergic neurons, preventing the apoptosis of GABAergic neurons, and promoting the production of GABA which is a neurotransmitter, and thus, the aucubin can be effectively used in the prevention or treatment of mental illnesses such as ADHD or autism, etc, which are caused by the deficiency of GABAergic neurons.
University-Industry Cooperation Group of Kyung Hee University
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Yunhee
Kim