Foley & Lardner LLP
D-pantolactone hydrolase and gene encoding the same
A novel enzyme which is useful in the optical resolution of D,L-pantolactone via D-selective asymmetric hydrolysis and a gene encoding the the same are provided. The invention discloses the gene coding for a natural D-pantolactone hydrolase (for example, one originating in Fusarium oxysporum) or proteins having an activity substantially equivalent thereto; host cells transformed with DNA containing a nucleotide sequence coding for said protein, processes for producing said protein via using said host cells and uses of said proteins and host cells.
Fuji Yakuhin Kogyo Kabushiki Kaisha
C C C C
C12P C12P C12P C12N
inventional inventional inventional inventional
Michihiko Hideaki Sakayu Keiji
Kobayashi Yamada Shimizu Sakamoto