Stevens, Davis, Miller & Mosher
Phenylbutanol derivatives
 Butyrophenone derivatives having excellent psychotropic activity and represented by the formula, ##SPC1## Wherein A represents a single or double bond linkage; R.sub.1 represents a hydrogen atom or a C.sub.1 - C.sub.4 alkyl group; R.sub.2, which is present only in case A represents a single bond linkage, represents a hydrogen atom, or a hydroxyl, C.sub.1 - C.sub.4 alkyl, or C.sub.1 - C.sub.4 alkoxy group; R.sub.3 represents a hydrogen atom, or a piperidino, pyrrolidino, morpholino, furyl, thienyl, C.sub.1 - C.sub.4 alkylamino, benzylamino, unsubstituted or halogen-substituted phenyl group, etc.; and X represents a hydrogen or halogen atom, or a C.sub.1 - C.sub.4 alkyl, C.sub.1 - C.sub.4 alkoxy, or trifluoromethyl group, can be prepared by reducing a benzoylpropionamide derivative of the formula, ##SPC2## Wherein A, R.sub.1, R.sub.2, R.sub.3 and X have the same meanings as defined above, to a phenylbutanol derivative of the formula, ##SPC3## 
Sumitomo Chemical Company, Ltd.
C C C
C07D C07D C07D
inventional inventional inventional
Isamu Kikuo Hisao Shigenari Masaru
Maruyama Sasajima Yamamoto Katayama Nakao