Sheridan Ross P.C.
Pharmaceutical composition comprising extract of Puerariae flos for prevention and treatment of endometriosis
The present invention relates to a pharmaceutical composition containing Puerariae Flos extracts as active ingredients for preventing or treating endometriosis and the complications thereof. More particularly, Puerariae Flos extracts exhibit the activity of inhibiting the migration and adhesion of endometriosis cells, inhibiting the expressions of MMP-2 and MMP-9, which are factors associated with migration and adhesion, inhibiting the expression of COX-2, which is a factor associated with pain, and inhibiting the expression of MCP-1, which is a cytokine associated with inflammation, and RANTES. Therefore, the Puerariae Flos extracts of the present invention can be effectively used as active ingredients for a pharmaceutical composition for preventing and treating endometriosis and the complications thereof, and for a health food.
University-Industry Cooperation Group of Kyung-Hee University
A A A
A23L A61K A61P
inventional inventional inventional
Ji-Hyyun Jung-Hye
Kim Choi