KIF18A inhibitors
Compounds of formula (I): as defined herein, and synthetic intermediates thereof, which are capable of modulating KIF18A protein thereby influencing the process of cell cycle and cell proliferation to treat cancer and cancer-related diseases. The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of KIF18A. 
AMGEN INC.
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C07D A61P C07D C07D C07D C07D C07D C07D
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Jonathan Dante Abhisek Ana Elena Matthew Paul Jian Jeffrey Nuria A.
Low Banerjee Minatti Bourbeau Chen Tamayo