Howard & Howard Attorneys PLLC
(2E)-3-phenyl-N-[2,2,2-Trifluoro-1-[[8-quinolineamino)thiomethyl]amino]ethyl]-2-acrylamide and pharmaceutical uses thereof
The present invention relates to an acrylamide compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof, to a composition comprising the compound or an isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluent, and to a use of the compound or the composition for prophylaxis and/or treatment of a disease or disorder associated with cardiomyocyte apoptosis.
Chinese PLA General Hospital
A A C
A61K A61P C07D
inventional inventional inventional
Xin Ruijin Lili Kunlun Long Guoliang Song Jie Hua Chunlei Junhai Wei Wu
Li Li Wang He Long Hu Li Wang Chen Liu Xiao Li Zhong