Brinks Gilson & Lione
Difluorolactam compositions for EP4-mediated osteo related diseases and conditions
Disclosed herein are compositions and methods of treating osteoporosis, bone fracture, bone loss, and increasing bone density by administration of compounds of formula (I)or compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier, wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification.
Cayman Chemical Company, Inc. Myometrics, LLC
A A C A C A A A A A A A A A A A A A C A A A A A A A A A
A61P A61P C07D A61L C07D A61P A61L A61P A61P A61P A61L A61P A61L A61P A61L A61P A61P A61P C07D A61L A61L A61K A61L A61P A61L A61L A61K A61L
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Fred Lawrence James Paul Andriy James Bernard Bradlee David Thomas Allen Stephen Douglas Gregory William Adam Joseph Michael
Ciske O'Malley Kornilov Kramer Germain Owen Barrett Endres Uzieblo Colombo