Abelman, Frayne & Schwab
Chitosan acrylic acid derivative hemostatic powder
The present invention provides a hemostatic powder. The hemostatic powder is mainly present in the form of a columnar particle, wherein the ratio of axial length to diameter of the columnar particle is less than 5; the hemostatic powder includes a polymer represented by the following structural formula: wherein the R is at least one selected from the group consisting of —NH2, —OCH2CH2OH, —OCH2CH2CH2OH, —OH, —ONa, —OK and —OCa; m, n and p respectively represent number percentages of corresponding repeating units in polymer molecules, and satisfy the following equations: m+n+p=1, p/(m+n+p)=0.05˜0.30; the substitution degree D is defined as =m/(m+n+p), the overall substitution degree of the columnar particle is defined as Ds, the substitution degree of the polymer at the center point of the cross section of the columnar particle is defined as Do, and the substitution degree of the polymer at the edge of the cross section of the columnar particle is defined as Dx, and the following equations are satisfied: Ds=0.09˜0.8, Do/Dx=0˜0.7. 
Jiangsu NewValue Medical Products Co., Ltd. Shnaghai Newvalue Medical Products Co., Ltd.
A A A A A A
A61K A61P A61K A61L A61L A61L
inventional inventional inventional additional inventional inventional
Liqin Shiming Zuguang Yingshan Rui Xiaoming
Xu Zhou Gong Zhou Jiang Zhou