Sughrue, Mion, Zinn, Macpeak & Seas
Purification of glycosaminoglycan degrading enzymes with a sulfated polysaccharide
 Glycosaminoglycan degrading enzymes are fractionated and purified by chromatographically treating a solution containing the enzymes with an insoluble sulfated polysaccharide carrier. The enzymes are adsorbed onto the carrier and then subsequently desrobed from the carrier. 
Seikagaku Kogyo Co., Ltd.
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inventional inventional inventional
Ken-ichi Hiroshi Keiichi
Maeyama Kikuchi Yoshida