Fitzpatrick, Cella, Harper & Scinto
Heterocyclic aromatic compounds useful as growth hormone secretagogues
Novel heterocyclic aromatic compounds are provided that are useful in stimulating endogenous production or release of growth hormone, said compounds having the general structure of formula Iwherein R1, R1′, R2, R3, R4, Xa, Y, Z and n are as described herein.The compounds provided herein are useful in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength.
Bristol-Myers Squibb Company
A A C C A A A A A A A A A A A A A A A C A A C A A A C A
A61P A61P C07D C07D A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C07D A61P A61P C07D A61P A61P A61P C07D A61P
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Guixue James J. Joseph Anthony Richard B. Jun William R.
Yu Li Tino Sulsky Li Ewing