Gray Cary Ware & Freidenrich, LLP
Methods to identify growth differentiation factor (GDF) binding proteins
The present invention provides receptors for the growth differentiation factor (GDF) family of growth factors and methods of identifying such receptors. Also included are methods of identifying antibodies which bind to the receptors, peptide fragments of the receptor which inhibit GDF binding, GDF receptor-binding agents capable of blocking GDF binding to the receptor. The receptors of the invention allow the identification of antagonists or agonists useful for agricultural and human therapeutic purposes.
The Johns Hopkins University School of Medicine
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Se-Jin Alexandra
Lee McPherron