Heterocyclic GPR40 modulators
The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I:where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.
Amgen Inc.
A A C A C C C A C A
A61P A61P C07D A61P C07D C07D C07D A61P C07D A61P
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Jiwen Hilary Michael J. Rajiv Jinqian Jonathan B. Zhihua Marc Paul Zhongyu SuJen Zice Yingcai Todd J. XianYun Julio C. Wang
Liu Beck Schmitt Sharma Liu Houze Ma Vimolratana Dransfield Wang Lai Fu Wang Kohn Jiao Medina Shen