Banner & Witcoff, Ltd.
Injectable pharmaceutical composition of tecovirimat and preparation method thereof
The present invention relates to a pharmaceutical composition of Tecovirimat for injection, comprising Tecovirimat as an active ingredient, cyclodextrin and an additive. The present invention also relates to a method for preparing the pharmaceutical composition. The composition improves the solubility of Tecovirimat in water by using cyclodextrin and meglumine in combination, as compared with the solubility of Tecovirimat in water by using cyclodextrin or meglumine alone.
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences PLA China
A A C A A B A C A A A A
A61K A61K C08B A61K A61P B82Y A61K C08L A61K A61K A61K A61K
inventional inventional inventional inventional inventional additional inventional inventional inventional inventional inventional inventional
Chunsheng Song Yuli Xinbo Wei Wu Meiyan
Gao Li Wang Zhou Gong Zhong Yang