Lex IP Meister, PLLC
Anti-aging transgenic Caenorhabditis elegans
The present invention relates to: a transgenic Caenorhabditis elegans in which a glutamine tRNA 5′ terminus-derived fragment (Gln 5′-tsRNA) is overexpressed; a preparation method therefor; and a method for screening for aging-associated factors by using the transgenic Caenorhabditis elegans. A transgenic Caenorhabditis elegans model provided in the present invention is an animal model in which Gln 5′-tsRNA is overexpressed such that aging is inhibited. When the model of the present invention is used, anti-aging mechanisms can be easily investigated, thereby significantly contributing to various research fields such as that of developing new anti-aging drugs and screening for age-inducing materials.
DAEGU GYEONGBUK INSTITUTE OF SCIENCE POSTECH ACADEMY-INDUSTRY FOUNDATION INSTITUTE FOR BASIC SCIENCE
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C12N G01N A01K G01N C12N A01K C12N A61K A01K C12N C12N A01K A01K A01K A01K G01N
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Gyoo Yeol Gi Won Seung Jae Mi Hwa Woo Seon Hong Gil
Jung Shin Lee Seo Hwang Nam