Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer
The present invention provides MDM2 inhibitor compounds of Formula I,
Amgen, Inc.
A C C C C A C C A C C C C C C A C C A C C A C A C C C C C
A61P C07D C07D C07D C07D A61P C07D C07D A61P C07D C07D C07D C07D C07D C07D A61P C07D C07D A61P C07D C07D A61P C07D A61P C07D C07D C07D C07D C07D
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Julie A. Zice Felix Yingcai Jiwen XianYun Michael W. Jeffrey Thomas Xiaodong Zhihua Philip M. Michael D. Brian M. Zhihong Xin Julio C. Daqing Hilary Plake Darin J. Xuelei Steven H. Benjamin Michael G. David John Jeffrey Ming Jiasheng Yosup Jonathan D. Jiang Joel Yihong Richard Victor Frank Lawrence R. Jason A. Brian S. John SuJen Ana Xiaoqi Dustin L.
Heath Fu Gonzalez Lopez De Turiso Wang Liu Jiao Gribble, Jr. Mihalic Wang Ma Roveto Bartberger Fox Li Huang Medina Sun Beck Gustin Yan Olson Fisher Johnson Kopecky Deignan Yu Fu Rew Low Zhu McIntosh Li Connors Kayser McGee Duquette Lucas Eksterowicz Lai Gonzalez Buenrostro Chen McMinn