Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by Lp-PLA2
The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease, and/or diabetic macular edema.
Glaxo Group Limited
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Yun Qing Zehong
Jin Zhang Wan