Clark & Elbing LLP
Polymeric coupling agents and pharmaceutically-active polymers made therefrom
A pharmaceutically-active polymeric compound of the general formula (I),Y-[Yn-LINK B-X]m-LINK B  (I)wherein (i) X is a coupled biological coupling agent of the general formula (II)Bio-LINK A-Bio  (II)wherein Bio is a biologically active agent fragment or precursor thereof linked to LINK A through a hydrolysable covalent bond; and LINK A is a coupled central flexible linear first segment of <2000 theoretical molecular weight linked to each of said Bio fragments;(ii) Y is LINK B-OLIGO; wherein
Interface Biologics Inc.
A A A A A A A A A C C A A A
A61K A61L A61L A61L A61K A61L A61K A61K A61L C08G C08G A61K A61L A61L
inventional additional additional additional inventional additional inventional inventional inventional inventional inventional inventional additional additional
J. Paul Mei
Santerre Li