Moore & Van Allen, PLLC
Bone graft and scaffolding materials immobilized with type I collagen binding peptides
The present invention relates to a pharmaceutical composition comprising a bone graft material, a scaffold for tissue engineering applications and type I collagen Binding Peptides which have bone calcification-promoting peptides immobilized on the surface, and more particularly, to a bone graft material and a scaffold for tissue engineering applications (hereinafter, referred to as scaffold), which have peptides specifically binding with type I collagen immobilized on the surface, and pharmaceutical composition for recovering tissue regeneration containing type I collagen binding-inducing peptide. In the inventive bone graft material and scaffold for tissue engineering applications, the cells related to regeneration by collagen binding-inducing peptide adhered to the surface, promote an adhesion of type I collagen binding-inducing peptide (main ingredients of extracellular matrix) to increase differentiation rate into bone tissues, and promote a calcification which is last step of bone regeneration to maximize a tissue regeneration finally.
Seoul National University Industry Foundation
A A A A A A
A61L A61L A61L A61L A61P A61P
inventional additional inventional inventional inventional inventional
Yoon-Jeong Seung-Jin Jue-Yeon Chong-Pyoung
Park Lee Lee Chung