Casimir Jones SC
PRC1 inhibitors and methods of treatment therewith
Provided herein are small molecule inhibitors of Polycomb Repressive Complex 1 (PRC1) activity, and methods of use thereof for the treatment of disease, including leukemia and other cancers, as well as other diseases dependent on the activity of PRC1.
The Regents of the University of Michigan
C A C C C A C A A C A C A C C A A C C A A C C A C
C07D A61K C07D C07D C07D A61K C07D A61K A61P C07D A61K C07D A61K C07D C07D A61K A61K C07D C07D A61K A61K C07D C07D A61K C07D
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Jolanta Yiwu Qingjie Felicia Tomasz Weijiang
Grembecka Yao Zhao Gray Cierpicki Ying