N-substituted-pyrrolidines as inhibitors of MDM2-P-53 interactions
There are provided compounds of the formulawherein X, Y, R1, R2, R3, R3, R4, and R5 are as described hereinand enantiomers and pharmaceutically acceptable salts and esters thereof which are useful as anticancer agents.
Hoffmann-La Roche Inc.
C C A A C C
C07D C07D A61P A61P C07D C07D
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Tina David Joseph Jin-Jun Zhuming Xin-Jie
Morgan Ross Bartkovitz Liu Zhang Chu