Sterne, Kessler, Goldstein & Fox P.L.L.C.
Joint product comprising synephrine and topiramate
The present invention provides a joint product comprising synephrine and topiramate, in which the synephrine or salt thereof is administered in form of rapid-release preparation, preferably rapid-release pellet, having daily dose of 2 mg to 25 mg, preferably 5 mg to 20 mg; the topiramate is administered in form of sustained-release or controlled-release preparation, preferably sustained-release pellet, having daily dose of 20 mg to 100 mg, preferably 23 mg to 92 mg. The composition is used for treatment of obesity or other diseases associated with obesity.
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
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Zhibing Li Wu Yuli Chunsheng Xinbo Xiaokui Song Meiyan
Zheng Shan Zhong Wang Gao Zhou Wang Li Yang