Bicyclic carboxamide inhibitors of kinases
Compounds of formula (I) or pharmaceutical acceptable salts are provided, wherein X1˜X5, R1˜R3, A, B, Z and n are defined in the description. And compositions containing said compounds, and the uses for inhibitors of kinases such as ALK, and the uses for treating cancer thereof are provided.
AbbVie Inc.
C A A A C C A
C07D A61P A61P A61P C07D C07D A61K
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Thomas Dale Huanming Bo Zhenguang Yan Anil Fengchun Cuihua Marina Shaohui
Penning Chen Liang Zou Shen Vasudevan Wu Liu Pliushchev Wang