Millen White Zelano & Branigan
Pyridone and aza-pyridone compounds and methods of use
Pyridone and aza-pyridone compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
GENENTECH INC. GILEAD CONNECTICUT, INC.
A C A A A A A C A A A A A A A A A A C A A A A C A A A C A A A A A A A A C C A A A A C
A61P C07D A61P A61P A61K A61K A61K C07D A61P A61P A61P A61P A61K A61P A61K A61P A61P A61P C07D A61K A61K A61P A61P C07D A61P A61P A61P C07C A61K A61P A61P A61K A61K A61P A61P A61P C07D C07F A61P A61P A61P A61P C07D
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Pavel E. Peter A. Aaron C. Jeffrey E. Antonio J. M. Kevin S. Ravi Jianjun Xiaojing Seung H. Scott A. Daniel Honglu Wendy Zhongdong
Zhichkin Blomgren Schmitt Kropf Barbosa Currie Krishnamoorthy Xu Wang Lee Mitchell Ortwine Zhang Young Zhao