Cancer treatment utilizing SP-141 to bind with MDM2 and act as an inhibitor of MDM2 expression
An SP-141 compound is a novel small molecule that can serve as a molecular-targeted chemotherapeutic agent. In one embodiment, the labeled compound can comprise SP-141, which comprises 6-methoxy-1-(naphthalen-1-yl)-9 H-pyrido[3,4-b]indote. The compound inhibits expression of oncogenes such as the Mouse Double Minute 2 protein. The compound can bind directly to Mouse Double Minute 2 to inhibit cancer growth including breast cancer growth.
Texas Tech University System
C
C07D
inventional
Wei Ruiwen
Wang Zhang