Novick, Kim & Lee, PLLC
Glycosylated oxalate decarboxylase and preparation and application thereof
The present invention discloses a glycosylated oxalate decarboxylase. The oxalate decarboxylase is derived from edible basidiomycetes, the glycosylated oxalate decarboxylase has an enzyme activity at the pH value of 1.5-7.5, the activity at the pH value of 1.5-2.0 is 10% greater than the optimum activity, and a specific activity is more than 2 U/mg. The present invention also discloses preparation and application of the glycosylated oxalate decarboxylase. The glycosylated oxalate decarboxylase disclosed by the present invention can keep the activity under a low pH value, and can effectively prevent and treat kidney stones.
WUHAN KANGFUDE BIOTECHNOLOGY CO., LTD.
A C A C A A A A C A
A61P C12N A61K C12N A61P A23L A23L A23V C12Y A23K
inventional inventional additional inventional inventional inventional inventional additional inventional inventional
Haifeng Huoqing Baoping Wei Xiaofeng Pei Xianqiao
Liu Chen Song Wang Wang Tong Chen