Dentons US LLP
Clonal strains of attenuated vaccinia viruses and methods of use thereof
Clonal strains of vaccinia viruses are provided. Also provided are methods of identifying and isolating attenuated and oncolytic clonal strains from virus preparations. Modified recombinant forms of the clonal strains also are provided. The clonal strains and virus preparations can be used for diagnostic and therapeutic methods, in particular for therapy and diagnosis or monitoring treatment of proliferative disorders, including neoplastic diseases, such as, but are not limited to, solid tumors and blood cancers.
Genelux Corporation
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C12N C12N C07K A61P A61K C12N A61P C07K A61P A61P C12N A61P A61P A61P A61P A61P
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Yong A. Aladar A. Nanhai G. Qian
Yu Szalay Chen Zhang