Imidazole compounds for the treatment of neurological disorders
The present invention relates to compounds of Formula Iwherein R1, R2, R3, R4, R6, R7 and A are as defined. Compounds of Formula I have activity inhibiting production of Aβ-peptide. The invention also relates to pharmaceutical compositions and methods for treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of Formula I.
Pfizer Inc
C C A A C C A C C C C A C C C A A C A C A A C C C C C C C A A C A
C07D C07D A61P A61P C07D C07D A61P C07D C07D C07D C07D A61P C07D C07D C07D A61P A61P C07D A61P C07D A61P A61P C07D C07D C07D C07D C07D C07D C07D A61P A61P C07D A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Brian T. Yuhpyng L. Michael A. Edward F. Karen J.
O'Neill Chen Brodney Kleinman Coffman