Birch, Stewart, Kolasch & Birch, LLP
Donepezil derivative and use thereof
The present invention relates to a donepezil derivative of general formula (I) or a pharmaceutically acceptable salt thereof, wherein R in the formula is as disclosed herein; and a method for preparation thereof; and a composition comprising an effective amount of a compound of the general formula (I) or a pharmaceutically acceptable salt thereof. The present invention also relates to use of a compound of the general formula (I) or a pharmaceutically acceptable salt thereof in preparing a medicament for treating a disease resulted from an abnormality in acetylcholinesterase activity.
NANJING NORATECH PHARMACEUTICALS CO., LTD.
A A A A C A A A A A A
A61K A61K A61K A61K C07D A61P A61K A61K A61K A61K A61K
inventional inventional additional inventional inventional inventional inventional inventional inventional inventional inventional
Wei Chenggang Cuixia Lulu Pan Fei Chunyan
Wang Lin Zhang Wang Chen Liu Zhou