McCarter & English, LLP
Substituted benzoimidazoles as modulators of ROR-γ
Provided are indole, benzoimidazole, pyrrolopyridine, and imidazopyridine derivatives and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORγ. Such derivatives include e.g., those having the Formula II:as well as pharmaceutically acceptable salts thereof. The disclosed derivatives may be used for treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.
Vitae Pharmaceuticals, LLC
C A A C C A C C C A C A C C A C A C A C A
C07D A61P A61P C07D C07D A61P C07D C07D C07D A61P C07D A61P C07B C07D A61P C07D A61P C07D A61P C07B A61P
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David A. Lawrence Wayne Yi Linghang Stephen D. Suresh B. Colin M. Wei
Claremon Dillard Fan Zhuang Lotesta Singh Tice Zhao