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Composition comprising compound inhibiting interactions of MBD2 and P66α for anti-metastasis and prevention and treatment of cancer disease
The present invention relates to a composition including an inhibitor against the function of an Mi-2/NuRD chromatin remodeling complex for inhibiting metastasis and preventing and treating cancer diseases, and more particularly, the composition may inhibit the MBD2-p66α (GATAD2A) interaction by means of the Mi-2/NuRD CRC function inhibitor, and thus is expected to be effectively used as a composition capable of inhibiting metastasis and preventing and treating cancer diseases.
University of South Florida Industry-University Cooperation Foundation Hanyang University
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A61P A61K A61K
inventional inventional inventional
Min Young Chul Geun Insung Young Su Yu Arjan Vladimir Dae Hyun Buom Yong Young Yiul
Kim Kim Na Lim Chen van der Vaart Uversky Ha Ryu Lee