Birch, Stewart, Kolasch & Birch, LLP
Acyclic nucleoside derivatives
Compounds of the Formula I where one of R1 and R2 is &#8212;C(O)CH(CH(CH3)2)NH2 or&#8212;C(O)CH(CH(CH3)CH2CH3)NH2;the other of R1 and R2 is &#8212;C(&boxH;O)C3-C21 saturated or monounsaturated, optionally substituted alkyl; andR3 is OH or H;and pharmaceutically acceptable salts thereof have utility as enhanced bioavailability antivirals against herpes and retroviral infections.
Medivir AB
A A C A Y C
A61P A61P C07D A61P Y02P C07D
inventional inventional inventional inventional additional inventional
M. Robert Michael Per Nils-Gunnar Xiao-Xiong Bjorn Marita
Leanna Rasmussen Engelhardt Johansson Zhou Lindborg Hogberg