7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates
A method is provided for preparing intermediates for 7-oxabicycloheptane carboxylic acid intermediates of the structures ##STR1## wherein R is alkyl, aryl, arylalkyl or cycloalkyl; R.sup.1 is alkyl, arylalkyl or cycloalkyl; R.sup.2 is aryl or arylalkyl; and of the structure ##STR2## where R and R.sup.1 are as defined above, which may be used in making the final anti-thrombotic--anti-vasospastic compounds.
Bristol-Myers Squibb Company
Wen-Sen Shankar Philip M. John J. Ambarish
Li Swaminathan Sher Venit Singh