Edwards Angell Palmer & Dodge LLP
Pyrimidine derivatives for treatment of hyperproliferative disorders
Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G′, and G″ represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
Bayer Pharmaceuticals Corporation
C C C A C C A A A C C A C C C C
C07D C07D C04B A61P C07D C07D A61P A61P A61P C07D C07D A61P C07D C07D C07D C07D
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Lei Wenlang Brian Lin Martin F. Julie A. Alexander Michael Ming Donald Jianqing Ann-Marie Dhanapalan Chunguang Yuanwei
Zhang Fu Bear Yi Hentemann Dixon Hillisch Brands Wang Bierer Chen Bullion Nagarathnam Wang Chen