Nelson Mullins Riley & Scarborough LLP
Chemical linkers and cleavable substrates and conjugates thereof
The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.
Medarex, Inc.
A C C A A C C A C A A C C A A C A A
A61K C07K C07K A61K A61P C07K C07D A61P C07D A61P A61K C07K C07K A61P A61K C07K A61K A61K
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Sanjeev Vincent Bilal David B. Liang Qian
Gangwar Guerlavais Sufi Passmore Chen Zhang