McCarter & English, LLP
Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment
The present application provides, among other things, a compound of Formula I-a and/or I-b,or a pharmaceutically acceptable salt thereof, wherein the variables are defined in the specification. The compounds of the invention are useful for treating various diseases including cancer.
Massachusetts Institute of Technology The Board of Trustees of the University of Illinois
C A C C
C07K A61K C07D C07D
inventional inventional inventional inventional
Paul J. Mohammad Karen Nicolas Justin
Hergenrother Movassaghi Morrison Boyer Kim