Marshall, Gerstein & Borun LLP
Acyl piperazine derivatives as TTX-S blockers
The present invention relates to acyl piperazine derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage gated sodium channels are involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which voltage gated sodium channels are involved.
Raqualia Pharma Inc.
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C07D A61K C07D C07D C07D A61K A61K A61P A61K A61P C07D C07D C07D C07D A61P C07D C07D A61P C07D A61P C07D A61P C07D A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Shuzo Mikiko
Watanabe Morita