Bachman & LaPointe, P.C.
Aminopeptidase derived from Bacillus licheniformis and process for preparation of natural type proteins
The present invention relates to a process for removing methionine (Met) residue at N-terminus of proteins specifically. Particularly, the present invention relates to an aminopeptidase which is purified from Bacillus licheniformis removes a methionine residue from N-terminus of peptide and proteins. And the present invention relates to a process for preparing a natural type protein from proteins produced in microorganisms by recombinant DNA technology. Various kinds of natural type proteins such as human growth hormone (HGH) can be prepared massively and easily by the process of the present invention.
LG Chemical Ltd.
C C
C12N C07K
inventional inventional
Kyuboem Se-Hoon Soon-Jae Seung-Joo Young-Phil
Han Kim Park Lee Lee