5-(Hydroxypyridylalkyl)-4-pyrimidones
 The compounds are substituted 2-amino-4-pyrimidones with a 5-(hydroxypyridylalkyl) substituent which are histamine H.sub.2 -antagonists. Two specific compounds are 2-[2-(3-bromo-2-pyridylmethylthio)ethylamino]-5-(2-hydroxy-4-pyridylmethyl )-4-pyrimidone and 2-[4-(3-methoxy-2-pyridyl)butylamino]-5-(2-hydroxy-4-pyridylmethyl)-4-pyri midone. 
Smith Kline & French Laboratories Limited
C C
C07D C07D
inventional inventional
Graham J. Thomas H. Charon R.
Durant Brown Ganellin