Process for preparing macrocyclic compounds
Disclosed is a process for preparing a macrocyclic compound of the formula (I) wherein a hydroxyl-substituted macrocyclic compound of formula (3) is reacted with a sulfonyl-substituted compound of formula QUIN:The compounds of formula (I) are potent active agents for the treatment of hepatitis C virus (HCV) infection.
Boehringer Ingelheim International GmbH
C C C A C C A
C07D C07D C07K A61P C07D C07K A61P
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Nizar Chris H. Azad Nathan K. Xudong Carl Alan Jianxiu Suresh R. Fabrice
Haddad Senanayake Hossain Yee Wei Busacca Liu Kapadia Gallou