Fitzpatrick, Cella, Harper & Scinto
Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use
The present invention is directed to compound of the formula I: wherein R1, R2, R3, R4, R5, X, Y, and are as defined herein. These compounds are useful for inhibiting the activity of a metalloproteinase by contacting the metalloproteinase with an effective amount of the inventive compounds.
Agouron Pharmaceuticals Inc.
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Arlindo L. Wesley K. M. Melwyn A. Roland J. Judith G. Jian Jeffrey Steven L.
Castelhano Chong Abreo Billedeau Deal Chen Bender