7H-azulene [1,2,3-i,j] isoquinolin-7-one compound, single crystal and use thereof
A 7H-azulene [1,2,3-i,j] isoquinolin-7-one compound, a single crystal and a use thereof are provided. The compound has a structure as shown in a formula (I). The present invention obtains a crude extract of Acorus calamus L., then extracts with different polar solvents in sequence and separates column chromatography to obtain a novel alkaloid compound, which is expected to be developed into a novel class of drug exerting neuroprotective effects, so as to prevent and treat senile dementia, stroke and epilepsy diseases.
HUNAN UNIVERSITY OF CHINESE MEDICINE
C A A B A A C A B B A
C07D A61K A61K B01D A61P A61K C07B A61P B01D B01D A61K
inventional inventional inventional inventional inventional inventional additional inventional inventional inventional inventional
Shunxiang Juan
Li Li