Heslin Rothenberg Farley & Mesiti P.C.
Pharmaceutical composition comprising cyclosporin solid-state microemulsion
 A pharmaceutical composition comprising a cyclosporin solid-state microemulsion is disclosed. In a preferred embodiment, the composition comprises a cyclosporin microemulsion dispersed in an enteric carrier. The composition does not dissolve in external phases such as artificial gastric fluid, but dissolves rapidly in artificial intestinal fluid, whereby it releases the cyclosporin microemulsion, providing rapid delivery of cyclosporin. The composition effectively maintains a therapeutic blood concentration of cyclosporin with once a day dosing, providing for convenience of administration and avoiding adverse effects induced by increasing peak blood cyclosporin concentrations associated with conventional cyclosporin formulations. 
Chong Kun Dang Corp.
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Su Geun Jung Woo Chung Il Chong Kook Jae Hyun Nam Hee Jong Lae Hee Jong
Yang Kim Hong Kim Kim Choi Lim Shin