McCarter & English LLP
Triazole compounds that modulate HSP90 activity
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Synta Pharmaceuticals Corp.
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Minghu Chi-wan Shijie Dinesh U. Howard P. Weiwen Kevin Hao Lijun Dan Zhenjian Junghyun Zachary Keizo Shuzhen Teresa David
Song Lee Zhang Chimmanamada Ng Ying Foley Li Sun Zhou Du Chae Demko Koya Qin Przewloka James