Brinks Hofer Gilson & Lione
Nucleic acids encoding secreted polypeptides that stimulate release of proteoglycans from cartilage
The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Genentech, Inc.
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C07K C07K C07H
inventional additional inventional
Mary A. Napoleone Mary E. Austin L. David Kevin P. William I. Kenneth J. Dan L. Audrey Daniel Margaret Ann Ivar J. J. Christopher Paul J. Ellen
Napier Ferrara Gerritsen Gurney Botstein Baker Wood Hillan Eaton Goddard Tumas Roy Kljavin Grimaldi Godowski Filvaroff