Birch, Stewart, Kolasch & Birch, LLP
Genetically modified microorganism and method for producing indigo dye
A genetically modified microorganism includes: an exogenous nucleic acid sequence encoding naphthalene dioxygenase (NDO), wherein the endogenous icd gene of the genetically modified microorganism is knocked out, in which the endogenous icd gene encodes isocitrate dehydrogenase (IDH), and wherein the genetically modified microorganism is capable of using glutamic acid and/or a salt thereof as a nitrogen source to grow and producing indigo dye.
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
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Hsiang-Yuan Pei-Ching Chang-Jung Jie-Len Ya-Lin Jhong-De
Chu Chang Chang Huang Lin Lin