Method for identifying compound for inhibiting an activity of a histone lysine demethylase
A method for identifying a compound that inhibits an activity of a histone lysine demethylase, in which the compound interacts with three sites of a pocket of the histone lysine demethylase generated by using a computer program, an alpha-ketoglutarate (AKG), a methylated lysine, and a NIQ.
NATIONAL TSING HUA UNIVERSITY
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G16B G16B C12Y G16B G01N G16B C12Q G16C G01N G16C
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Jing-Moon Chia-Han Wen-Ching Hsing-Jien
Yang Chu Wang Kung