Hoffmann & Baron, LLP
Neutralizing human monoclonal antibody 8D6 against HCV infection
Provided herein is a human monoclonal antibody 8D6 against hepatitis C virus (HCV) infection. The antibody binds to the E2 subunit of HCV capsid protein, and can prevent HCV from infecting susceptible host cells. By using the antibody variable region gene or the complementary determining region (CDR) gene, different forms of genetic engineering antibodies have been transformed and produced in any expression system of the prokaryotic and eukaryotic cells as therapeutics to prevent or treat HCV infection.
SUZHOU GALAXY BIOPHARMA, CO., LTD.
C G C C G C G A A C
C07K G01N C07K C07K G01N C12N G01N A61K A61P C07K
additional inventional additional inventional inventional inventional additional inventional inventional additional
Jiangjun Jie Honglin Chao Xin Bing Zhiyang Chunyan
Wang Liu Zhou Bian Dong Sun Ling Yi