Branched 3- and 6-substituted quinolines as CGRP receptors antagonists
The present invention is directed to novel branched 3- and 6-substituted quinoline derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Merck, Sharp & Dohme, Corp.
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A61P A61P A61P A61P A61P C07D A61P
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Kathy June J. Michael R.
Schirripa Kim Wood