Foley & Lardner LLP
Methods of treatment using recombinant oxalate oxidase
Novel oxalate oxidases are provided, which have suitable oxalate degrading activity near physiological pH (7.4). The properties of these OxOx make them potential drug candidates for use in reducing oxalate concentration in patients suffering from excess of oxalate. Especially due to the high activity at physiological pH, the OxOx's are suitable drug candidates for parenteral administration, i.e. to reduce the oxalate concentration in the plasma.
NEXTTOBE AB
A C C
A61K C12Y C12N
inventional inventional inventional
Xiaofeng Yi Wei Haifeng
Wang Wang Wang Liu