Connolly Bove Lodge & Hutz LLP
Method of transducing a protein into cells
The invention relates to a method for transducing a pharmaceutical protein or polypeptide that may be fluorescently labeled into a cell by forming a conjugate with a cationic polymer having cation values of more than 2 and no more than 250 and transducing the conjugate into the cell. The protein or peptide pharmaceutical agent is directly covalently bound to the cationic polymer or is covalently bound to the cationic polymer through a bifunctional crosslinking agent.
Nippon Shokubai Co., Ltd.
A
A61K
inventional
Hidetaka Junichiro Hidenori
Nakanishi Futami Yamada