New England Biolabs, Inc.
High fidelity restriction endonucleases
Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.
New England Biolabs, Inc.
G C C C C C C G
G01N C12Q C12N C12Q C12Q C12Y C12N G01N
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Shuang-Yong Chunhua Aine Siu-hong Xuhui Yishu Dapeng Shengxi Zhenyu Xianghui
Xu Zhang Quimby Chan Lai Huang Sun Guan Zhu Li