Banner & Witcoff, Ltd.
Piperazinyl pyrimidine derivatives, preparation method and use thereof
Provided are piperazinyl pyrimidine derivatives of formula I having CCR4 antagonism, and the preparation method, pharmaceutical composition and use thereof in the preparation of a medicament. The medicament is useful for the treatment and prevention of CCR4-related diseases.
The Institute of Pharmacology and Toxicology Academy of Military Medical Science P.L.A. CHINA PEKING UNIVERSITY
A C C A A C C C C A A A A A A A A
A61P C07D C07D A61P A61P C07D C07D C07D C07D A61P A61P A61P A61P A61P A61P A61P A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Guoming Song Lili Ying Enquan Dalong Hongying Hongwei Zhibing Yunde Hui Meina Junhai Wu Jing Xingzhou Xinbo Xiaokui Yang Xiaomei
Zhao Li Wang Wang Xu Ma Liu Gong Zheng Xie Qi Li Xiao Zhong Ma Li Zhou Wang Zhang Ling