Kirton McConkie
Lactone hydrolase and method of degrading alpha-zearalenol using the same
A lactone hydrolase having improved activity towards α-zearalenol is disclosed. The lactone hydrolase has a modified amino acid sequence of SEQ ID NO: 5, wherein the modification is a substitution of valine at position 167 with histidine. A method of degrading α-zearalenol using such lactone hydrolase is also disclosed.
TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES
A C A C A A
A23K C12Y A23K C12N A23L A23K
inventional inventional inventional inventional inventional inventional
Rey-Ting Chun-Chi Je-Ruei Weidong Wei Zhongxia Yingying Yanhe
Guo Chen Liu Liu Peng Xu Zheng Ma