Sidley Austin LLP
IL-17 homologous polypeptides and therapeutic uses thereof
The present invention is directed to novel polypeptides having sequence identity with IL-17 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders.
Genentch, Inc.
C A C C C A C A C
C07K A61K C07K C12N C07K A61P C07K A61P C07K
inventional additional inventional additional inventional inventional additional inventional additional
Ellen Jian Hanzhong Austin Audrey William I.
Filvaroff Chen Li Gurney Goddard Wood