Purdue Pharma L.P.
Phenylpropionamide compounds and the use thereof
The invention relates to phenylpropionamide compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein A, B, R1, R2, R3, R4 and R5 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula (I) to treat, prevent or ameliorate a disorder responsive to the activation of opioid receptors, particularly μ-opioid receptors. Compounds of the present invention are especially useful for treating pain.
Purdue Pharma L.P.
A A A A A A A C A A C A A A A
A61P A61K A61P A61K A61P A61P A61P C07D A61K A61P C07D A61P A61P A61P A61P
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Xiaoming
Zhou