Pai Patent & Trademark Law Firm
Thermal responsive composition for treating bone diseases
Thermal responsive compositions for treating bone diseases are provided. The thermal responsive composition for treating bone diseases includes a bone growth factor and a biodegradable copolymer. The biodegradable copolymer has a structure of Formula (I) or Formula (II):A-B-BOX-B-A  Formula (I)B-A-B-(BOX-B-A-B)n-BOX-B-A-B  Formula (II)wherein, A includes a hydrophilic polyethylene glycol polymer, B includes a hydrophobic polyester polymer, BOX is a bifunctional group monomer of 2, 2′-Bis(2-oxazoline) and used for coupling the blocks A-B or B-A-B, and n is an integer and the same or more than 0.
Industrial Technology Research Institute
A A A A A A A A
A61L A61P A61L A61L A61L A61P A61L A61L
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Meng-Yow Jui-Sheng Tsai-Yu Wei-Lin Liang-Yo Chih-Hung Hsin-Hsin Shen-Hua Pei-Shan Yi-Hung Po-Liang
Hsieh Sun Lin Yu Yang Chang Shen Peng Li Lin Lai