Substituted 3-amino-thieno[2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
Disclosed are compounds of formula (I):wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
Boehringer Ingelheim Pharmaceuticals, Inc.
C A A A A A C A A A A A A A A A A A A C A A A A A A A A A A A
C08G A61P A61P A61P A61P A61K C07D A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C08G A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61K
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Charles L. Weimin Tina Zhidong Jiang-Ping Daniel Richard Peter Roman Wolfgang Ming-Hong Jonathan Eugene Ronald John Sanxing
Cywin Liu Morwick Chen Wu Marshall Nemoto Fleck Hao Emeigh Hickey Sorcek Sun