The PL Law Group, PLLC
Botulinum toxin-human epidermal growth factor fusion protein with increased skin cell proliferation and anti-oxidation effect and cosmetic composition for regenerating skin and improving skin wrinkle comprising the same as effective component
A botulinum toxin-human epidermal growth factor fusion protein with increased skin cell proliferation and anti-oxidation effect has the amino acid sequence of SEQ ID NO: 2, a gene consisting of E. coli (Escherichia coli) codon-optimized nucleotide sequence of SEQ ID NO: 1 for encoding the botulinum toxin-human epidermal growth factor fusion protein, a recombinant vector including the gene, a host cell transformed with the recombinant vector, and a method for producing a botulinum toxin-human epidermal growth factor fusion protein by transforming a host cell with the recombinant vector, and a cosmetic composition for regenerating skin and improving skin wrinkle including, as an effective component, a botulinum toxin-human epidermal growth factor fusion protein, and as the cosmetic composition has an effect of regenerating skin and improving skin wrinkle, it can be advantageously used in future in the field of cosmetics or cosmetic plastic surgery.
NEXGEN BIOTECHNOLOGIES, INC.
C C A C A A C C C C A A C A
C12N C07K A61K C12Y A61Q A61K C12N C07K C12N C07K A61Q A61K C07K A61K
inventional additional inventional inventional inventional inventional inventional inventional inventional additional inventional inventional inventional inventional
Tae Hwa Tae Hyun Hyeong Il Seong Ran Tae Won Sun Kyo Han Bong Jong Nam
Jeong Kim Kwon Lee Choi Lee Ryu Choi