Tarolli, Sundheim, Covell & Tummino LLP
Method of generating tumor-specific T cells
A method for the expansion of tumor-specific T-cells includes obtaining an enriched population of T-cells from a subject with cancer; and contacting the enriched population of T-cells ex-vivo with: (i) an anti-CD3 antibody, an anti-CD28 antibody, and/or functional fragments thereof, and (ii) a VEGF inhibitor, to activate and expand the T-cells.
Case Western Reserve University
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Julian Mei Hallie Anthony
Kim Zhang Graor Visioni