Sterne, Kessler, Goldstein & Fox P.L.L.C.
Monoclonal antibodies against frizzled
Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided.
ONCOMED PHARMACEUTICALS, INC.
C A A C C C C C C A G A C C C C A C C C C A C C A A C C A
C07K A61P A61K C07K C07K C07K C07K C07K C07K A61K G01N A61P C07K C07K C07K C07K A61K C07K C07K C07K C07K A61K C07K C07K A61K A61K C07K C07K A61K
inventional inventional inventional additional additional additional inventional additional additional additional inventional inventional inventional inventional additional additional inventional additional additional inventional additional inventional inventional additional inventional inventional additional additional inventional
Sanjeev H. Satyajit Sujit Kumar Austin L. Timothy Charles Aaron Ken Fumiko Takada
Satyal Mitra Gurney Hoey Sato Axelrod