Fisher, Christen & Sabol
4-Hydroxy-5,6,7,8-tetrahydroquinoline-3-carboxylic acids and derivatives
 Disclosed is a quinoline derivative having the general formula ##STR1## where A represents a six-membered hydrocarbon ring; X represents an oxygen atom, an .dbd.NOR.sup.1 group in which R.sup.1 is a hydrogen atom or a lower alkyl radical of from 1 to 5 carbon atoms, a hydroxyl group, or an --NHR.sup.2 group in which R.sup.2 is a hydrogen atom or an acyl group; and Y represents a hydrogen atom, a salt-forming radical, or an ester-forming radical. This quinoline derivative is a novel compound which has antiallergic effects in itself and is useful as an intermediate in the production of penicillin or cephalosporin derivatives. 
Mitsui Toatsu Chemicals, Incorporated
C
C07D
inventional
Akira Hideaki Takuo Makoto
Matsubara Sakai Nakano Odate