Wilson Sonsini Goodrich & Rosati
Phenylamino isothiazole carboxamidines as MEK inhibitors
The invention concerns compounds which inhibit MEK and which have activity as anti-neoplastic agents. These compounds include N-substituted-3-hydroxy-5-arylamino-isothiazole-4-carboxamidines. Also included are the tautomeric isothiazol-3(2H)-ones.
Ardea Biosciences, Inc.
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A61P C07D C07D C07D C07D C07D C07D
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Robert Andreas Hassan Stanley Huanming Zhi Dinesh Varaprasad
Tam Maderna Abdellaoui Lang Chen Hong Barawkar Chamakura