Wolf, Greenfield & Sacks, P.C.
Methods for killing PSMA-expressing, taxane-resistant cancer cells
Methods of killing prostate-specific membrane antigen (PSMA)-expressing, taxane-resistant cancer cells are provided. In particular, PSMA-expressing, taxane-resistant cancer cells are contacted with an antibody-drug conjugate (ADC) that comprises an antibody or antigen-binding fragment thereof that specifically binds to PSMA conjugated to monomethylauristatin norephedrine or monomethylauristatin phenylalanine.
PSMA Development Company, LLC
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A61K A61P A61K A61P
inventional inventional inventional inventional
Robert J. Stephen William C. Dangshe
Israel Morris Olson Ma