Townsend and Townsend and Crew LLP
Amorphous cefuroxime axetil and preparation process therefore
A novel process for the preparation of amorphous cefuroxime axetil particles and the amorphous cefuroxime axetil particles therefrom are disclosed in the invention. Specifically, the invention is implemented by means of antisolvent recrystallization to prepare the cefuroxime axetil in an amorphous form; particularly, the amorphous ultrafine or even nanosized cefuroxime axetil with a controllable particle size and a narrow particle size distribution. The cefuroxime axetil according to the invention can used to enhance bioavailability, since it is in an amorphous form and has a controllable particle size and a narrow particle size distribution.
Nanomaterials Technology Pte Ltd. Beijing University of Chemical Technology
C A
C07D A61P
inventional inventional
Jianfeng Zhigang Jie Jiyao
Chen Shen Zhong Zhang