Greenlee Winner and Sullivan, PC
Protein production in Aureobasidium pullulans
The present disclosure provides methods and DNA molecules for the synthesis of heterologous proteins in the fungus Aureobasidium pullulans either intracellularly or with secretion out of the cells using a regulated xylanase promoter and for secreted protein synthesis, a signal sequence. Further described are kits containing host cells for recombinant protein production, a vector containing an XynA transcription regulatory sequence, and instructions for using the vector to transform the host cells.
University of Georgia Research Foundation, Inc.
C C
C07K C12N
inventional inventional
Xin-Liang Lars G.
Li Ljungdahl