The PL Law Group, PLLC
Composition for ameliorating, or treating depression and anxiety disorder comprising Fraxinus rhynchophylla extract as effective ingredient
A method for preventing or treating at least one of depression and anxiety disorder according to an embodiment of the present invention includes administering to a subject in need thereof a composition having an extract of Fraxinus rhynchophylla as an effective ingredient. By having an effect of improving depressive behavior and low physical activity shown in an animal model with induced anxiety and depression, reducing the level of cortisol, increasing the level of serotonin, and also increasing the expression amount of pCERB, BDNF, and mBDNF proteins in hippocampal tissues, the compositions can be advantageously used for developing a functional health food product or a pharmaceutical product for ameliorating or treating the depression and anxiety disorder.
KOREA INSTITUTE OF ORIENTAL MEDICINE
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Yu Ri Mi Young Bo-Kyung Young Hwa
Kim Lee Park Kim