Sterne Kessler Goldstein & Fox PLLC
Methods of using antibodies that bind the glutamate ligand binding region of Notch1
Isolated antibodies that specifically binds to an extracellular conserved ligand binding region of a human Notch receptor and inhibits growth of a tumor are described. Also described are methods of treating cancer, the method comprising administering an anti-Notch antibody in an amount effective to inhibit tumor growth.
OncoMed Pharmaceuticals, Inc.
A Y C C A C C C C C C A C C C C A A A A C
A61K Y10S C07K C07K A61K C07K C07K C07K C07K C07K C07K A61K C07K C07K C07K C12N A61P A61P A61K A61K C07K
inventional additional additional additional inventional additional additional additional additional additional additional additional additional additional inventional additional inventional inventional additional additional inventional
Austin Maureen Aaron
Gurney Fitch-Bruhns Sato