Wenderoth, Lind & Ponack, L.L.P.
Optically active nitro alcohol derivatives, optically active amino alcohol derivatives, and process for preparing the same
Optically active 1-substituted phenyl-2-nitro alcohol derivatives having the formula (1) and the process for producing thereof, and 1-substituted phenyl-2-amino alcohol derivatives having the formula (2) and the process for producing thereof from the optically active 1-substituted phenyl-2-nitro alcohol derivatives. From these nitro alcohols, pharmaceuticals such as (R)-albutamin and (R)-sarmeterol useful as a bronchodilator is obtained via optically active amino alcohols which are useful pharmaceutical intermediates.
Chisso Corporation
B B C C C C C C C C C C C B C B B C C C C
B01J B01J C07D C07D C07C C07B C07F C07C C07C C07C C07C C07C C07C B01J C07C B01J B01J C07C C07C C07F C07C
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Masakatsu Hiroaki Mamoru Yasuo
Shibasaki Sasai Fujita Urata