Genomic Health/McNeill Baur PLLC
Gene expression profile algorithm and test for likelihood of recurrence of colorectal cancer and response to chemotherapy
Algorithm-based molecular assays that involve measurement of expression levels of prognostic and/or predictive genes, or co-expressed genes thereof, from a biological sample obtained from a cancer patient, and analysis of the measured expression levels to provide information concerning the likelihood of recurrence of colorectal cancer and/or the likelihood of a beneficial response to chemotherapy for the patient are provided herein. Methods of analysis of gene expression values of prognostic and/or predictive genes, as well as methods of identifying gene expression-tumor region ratios, tumor-associated stromal surface area, and gene cliques, i.e. genes that co-express with a validated biomarker and thus may be substituted for that biomarker in an assay, are also provided.
Genomic Health, Inc.
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G01N C12Q G01N C12Q C12Q G16Z C12Q G01N G16H
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Kim Drew Lawrence Xitong Steven
Clark-Langone Watson Lee Li Shak