Knobbe Martens Olson & Bear
Binding domains from plasmodium vivax and plasmodium falciparum erythrocyte binding proteins
 The present invention provides isolated polypeptides useful in the treatment and prevention of malaria caused by Plasmodium falciparum or P. vivax. In particular, the polypeptides are derived from the binding domains of the proteins in the DBL family as well as the sialic acid binding protein (SABP) on P. falciparum merozoites. The polypeptides may also be derived from the Duffy antigen binding protein (DABP) on P. vivax merozoites. 
The United States of America as represented by the Secretary, Department of Health and Human Services
A C A Y
A61K C07K A61P Y02A
additional inventional inventional additional
Louis H. Xin-Zhuan Chetan David S. Thomas E. Kim Lee
Miller Su Chitnis Peterson Wellems Sim