Cyanoamido-containing heterocyclic compounds useful as reversible inhibitors of cysteine proteases
Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formulas (Ia) and (Ib) where R1, R2, R3, R4, R5, R6, R8, R9 and X are defined herein. The compounds are useful for treating autoimmune and other diseases. Also disclosed are processes for making such novel compounds
Boehringer Ingelheim Pharmaceuticals, Inc.
A A A C A A C A A A A C A A C C C A A A C A A C C C A C A A
A61P A61P A61P C07C A61P A61P C07D A61P A61P A61P A61P C07D A61P A61P C07D C07C C07D A61P A61P A61P C07D A61P A61P C07D C07C C07C A61P C07C A61P A61P
inventional inventional inventional additional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional additional inventional inventional inventional inventional inventional inventional inventional inventional inventional additional inventional inventional inventional inventional
Younes Usha R. Denice Mary Yancey D. Eugene R. Erick R. R. David S. Sanxing Weimin
Bekkali Patel Spero Ward Hickey Young Thomson Sun Liu