Antibodies specific for Trop-2 and their uses
The present invention provides antibodies that specifically bind to trophoblast cell-surface antigen-2 (Trop-2). The invention further provides antibody conjugates comprising such antibodies, antibody encoding nucleic acids, and methods of obtaining such antibodies. The invention further relates to therapeutic methods for use of these antibodies and Trop-2 antibody conjugates for the treatment of a condition associated with Trop-2 expression (e.g., cancer), such as colon, esophageal, gastric, head and neck, lung, ovarian, or pancreatic cancer.
Rinat Neuroscience Corp.
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David Louis Arvind Pavel Shu-Hui Magdalena Grazyna Wei-Hsien Thomas-Toan
Shelton Rajpal Strop Liu Dorywalska Ho Tran