Banner & Witcoff, Ltd.
Biodegradable medical adhesive and preparation method and use thereof
A medical adhesive with good biodegradable performance capable of undergoing crosslinking copolymerization, comprising a mono-alpha-cyanoacrylate and a bis-alpha-cyanoacrylic acid diol ester monomer molecule. The olefinic bonds in the mono-alpha-cyanoacrylate structure are polymerized in the presence of infinitesimal anions to form a solid 3D high polymer; the 3D high polymer is provided with degradation sites on the web-like backbone chain, with clear degradation path and absorbable degradation products. The medical adhesive can be used for wound adhesive, large area wound hemostasia, and visceral and soft tissue wound closure.
INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHENGDU YIPING MEDICAL SCIENCE & TECHNOLOGY CO. LTD
A C C C C C C A A A C
A61L C08F C09J C08F C09J C08F C09J A61L A61L A61L C08L
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Liang Keliang Qingsong Dazhen Qingbin
Xu Liu Zhang Cai Meng