Sterne, Kessler, Goldstein & Fox P.L.L.C.
Fused 1-(2,6-dichloro-4-trifluoromethylphenyl)-pyrazoles, the synthesis thereof and the use thereof as pesticides
The present invention is directed to novel pyrazole derivatives and their use as pesticidal agents. The pyrazole derivatives have Formula I: or a salt thereof, whereR1 is amino, hydrogen, alkyl, hydroxy, halo, alkoxy, alkylamino, dialkylamino, alkylthio, alkylsulfinyl, alkylsulfonyl, trifluoroalkylsulfinyl, trifluoroalkylsulfonyl, hydroxy, amino, trifluoromethyl, acetylamino, &#8212;OSO2R2, &#8212;OS(O)R2, &#8212;OC(O)R2, &#8212;OC(O)NHR2, or &#8212;NHC(O)NHR2 where R2 is C1-4 alkyl or optionally substituted aryl;X, Y and Z are each independently (CH)n, (CR3R4)n, S, S(O), or SO2, wherein n is 1-2, R3 and R4 are defined herein;Q is N or C&#8212;R6, wherein R6 is fluoro, chloro, bromo, or iodo;R5 is halo, C1-C6 alkyl, C1-C4 alkenyl, C1-C4 alkoxy, C1-C4 alkylamino, C1-C4 dialkylamino, C1-C4 alkylthio, C1-C4 alkylsulfinyl, C1-C4 alkylsulfonyl, C1-C4 trifluoroalkylsulfinyl, C1-C4 trifluoroalkylsulfonyl, hydroxy, amino, or trifluoromethyl; andwith the proviso that only one of X, Y and Z can be S, S(O) or SO2.
3-Dimensional Pharmaceuticals, Inc.
C A C C C C C C A
C07D A01N C07D C07D C07D C07D C07D C07D A01N
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Dario Richard M. Yu-Kai Sanath Ruiping Gary Daljit S. Deyou
Doller Soll Lee Meegalla Liu Silver Dhanoa Sha