McCarter & English LLP
Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1
Disclosed are compounds represented by Formula (I):or pharmaceutically acceptable salts, enantiomers or diastereomers thereof. Also disclosed are pharmaceutical compositions comprising the compounds of Formula (I) or pharmaceutically acceptable salts, enantiomers or diastereomers thereof for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. Values for the variables of Formula (I) are defined herein.
Vitae Pharmaceuticals, Inc.
C A A A A A A A A A A A A A A A A C A A A
C07D A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C07D A61P A61P A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Colin M. Yuanjie Katerina Wei Linghang David A. Suresh B.
Tice Ye Leftheris Zhao Zhuang Claremon Singh