Kilpatrick Townsend & Stockton, LLP
Drug inclusion complex, preparation thereof, and preparation method thereof
A pharmaceutical composition comprises an active component KX2-361 represented by formula 1 or a medicinal salt thereof and hydroxylpropoxyl-β-cyclodextrin. An inclusion compound is formed by KX2-361 or the medicinal salt thereof and hydroxylpropoxyl-β-cyclodextrin, and the solubility of the poorly-soluble drug KX2-361 is improved. The pharmaceutical composition can be prepared into an intravenous preparation and an oral preparation.
GUANGZHOU XIANGXUE PHARMACEUTICAL CO., LTD.
A A A A A A A A A A
A61K A61P A61K A61K A61K A61K A61P A61K A61K A61K
inventional inventional additional inventional inventional inventional additional inventional inventional inventional
Huihong Qingyong Daxin Ronghua Yan Shuiping Lun
Chen Zhang Ou Zhao Liu Shi Zeng