Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
Pyridopyrimidine derivatives and use thereof
The invention provides novel substituted pyridopyrimidines represented by Formula I or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of the phosphoinositide 3′ OH kinase family (PI3K) for the treatment of inflammatory diseases, cancer, cardiovascular diseases, allergy, asthma and autoimmune disorders.
Sung Kwang Medical Foundation CMG Pharmaceutical Co., Ltd.
C C
C07D C07D
inventional inventional
Jung Jin Albert C. Eun Kyung Jeongbeob Gilnam Choung Soo Chul Soo Hee Jung Han Won Jin Sung Suk Young Yong Wha
Hwang Gyorkos Choi Seo Lee Kim Lim An Cho Kim Cho Moon