Jones Day
CXCR3 antagonists
Compounds, compositions and methods that are useful in the treatment of inflammatory and immune conditions and diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of a chemokine receptor. The subject methods are useful for the treatment of inflammatory and immunoregulatory disorders and diseases, such as multiple sclerosis, rheumatoid arthritis and type I diabetes.
Amgen SF, LLC
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An-Rong Andrew P. Jiwen Alan Xi Michael G. Liusheng Julio C.
Li Marcus Liu Huang Johnson Zhu Medina