Seed IP Law Group PLLC
PKM2 modulators and methods for their use
Compounds having activity as PKM2 activators are disclosed. The compounds have the following structure (I): including stereoisomers, tautomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Tolero Pharmaceuticals, Inc.
C C C A C A C C C C C C A C C A C C C
C07D C07D C07D A61K C07D A61P C07D C07D C07F C07D C07D C07D A61P C07D C07D A61P C07D C07D C07D
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Kenneth Mark David Lee Scott Albert Michael David Yong Koc-Kan Kevin Bret Steven Brian Jihua Jason Marc Xiaohui
Parnell Vollmer Pearce Saunders Xu Ho Wright Kanner Liu Foulks Liu