Polynucleotide encoding a novel human serpin secreted from lymphoid cells, LSI-01
The present invention provides novel polynucleotides encoding LSI-01 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel LSI-01 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
Bristol-Myers Squibb Company
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A61P A61P C07K A61P A61P C07K A61P A61K
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Daniel L. Thomas Jian
Cheney Nelson Chen