Nixon Peabody LLP
Solid state forms of racemic ilaprazole
The invention relates to crystalline forms of racemic ilaprazole, 2[[(4-methoxy-3-methyl-2 -pyridinyl)-methyl]sulfinyl]-5-(1 H-pyrrol-1-yl) 1H-Benzimidazole. The invention also relates to a pharmaceutical composition for inhibiting gastric acid secretion comprising a crystalline Form of ilaprazole according to the invention in an amount effective to inhibit gastric acid secretion and a pharmaceutically acceptable carrier. The invention also provides methods of treatment for various acid-related gastrointestinal (GI) disorders.
IL Yang Pharmaceutical Company, Ltd.
A C A A
A61P C07D A61P A61P
inventional inventional inventional inventional
David T. Wei John M. Jinyu Jih Hua Stephan D.
Jonaitis Lai Brackett Shen Liu Parent