Squire Patton Boggs (US) LLP
Aminoquinazoline derivatives and their salts and methods of use thereof
Provided herein are aminoquinazoline compounds, salts and uses thereof. The compounds have Formula (I), or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof. Also provided herein are pharmaceutical compositions containing the compounds disclosed herein, and uses of the compounds or the compositions for preventing, managing, treating or lessening the severity of a proliferative disorder in a patient and for modulating the protein tyrosine kinase activity.
SUNSHINE LAKE PHARMA CO., LTD.
A A C A A C A A A C A C A A A C C A C C A A A A A A A A A A A C C A A C A A A A A A A A
A61K A61K C07D A61P A61P C07D A61K A61P A61K C07D A61K C07D A61P A61K A61K C07D C07D A61P C07D C07D A61P A61K A61K A61K A61K A61K A61K A61P A61K A61P A61K C07D C07D A61K A61P C07D A61K A61K A61K A61K A61P A61K A61P A61K
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional additional
Yingjun Jiancun Bing Jinlei Changchung
Zhang Zhang Liu Liu Cheng