Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
Process for producing toluidine compound
Because fluazinam is excellent as an active ingredient of pesticides and highly useful, it is desired to produce it efficiently in a proper form with simple operations at low cost in an environmentally friendly manner. The desired product is obtained in good yields with simple operations by using industrially advantageous reaction systems by a process comprising (1) a step of reacting ACTF and DCDNBTF in the presence of an alkali component, a solvent selected from the group consisting of ketones, nitriles, ethers and esters and a sufficient amount of water to substantially dissolve the alkali component, (2) a step of neutralizing or acidifying the reaction mixture with an acid and (3) a step of removing the solvent by distillation from the mixture containing fluazinam as the reaction product and the reaction solvent to precipitate crystals the product.
Ishihara Sangyo Kaisha, Ltd.
C
C07D
inventional
Akihiko Katsuyoshi Takayoshi Hiroshi Shigeo Takeshi Norio Tadashi
Isogai Murakami Ando Yoshizawa Murai Ohshima Adachi Nakamura