Wolf, Greenfield & Sacks, P.C.
Markers for mood disorders
Disclosed is a method for diagnosing a mood disorder or susceptibility to a mood disorder, including depressive disorders and bipolar disorder, from a biological sample taken from a subject. The method includes detecting markers of monoamine oxidase-A (MAO-A) in the biological sample; determining MAO-A concentration from the markers; and correlating the MAO-A concentration in the biological sample to a control group which does not have a mood disorder in order to diagnose or determine susceptibility to the mood disorder in the subject. Also disclosed is a method of detecting peripheral markers of MAO-A for the diagnosis of a mood disorder or susceptibility to a mood disorder. Also provided are polypeptide markers.
CENTRE FOR ADDICTION AND MENTAL HEALTH
A C G C G C G C C G C C A
A61B C12Y G01N C07K G01N C12N G01N C12Q C07K G01N C40B C12Q A61B
inventional inventional additional inventional additional inventional additional inventional inventional inventional inventional inventional inventional
Suzanne Jian Jeffrey Moyez Ken
Ackloo Chen Meyer Dharsee Evans