Craig & Antonelli
Butyrophenone derivatives and production thereof
 A process for producing butyrophenone derivatives of the formula: ##EQU1## which comprises reacting a compound of the formula: ##SPC1## With an amine of the formula EQU H-W (wherein Ar represents a group of either one of the formulas: ##SPC2## Z is a secondary amino group and W is the residue of an amine excluding a hydrogen atom therefrom). The said butyrophenone derivatives and their salts exhibit a variety of beneficial pharmacological activities including a central and autonomic nervous system depressing activity. 
Sumitomo Chemical Company, Limited
C C C C C A A A C A
C07D C07D C07D C07C C07C A61P A61P A61P C07D A61P
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Shigenari Shigeho Keiichi Isamu Masaru Masaharu Junki Hisao Kikuo
Katayama Inaba Ono Maruyama Nakao Takayama Katsube Yamamoto Sasajima