Scully, Scott, Murphy & Presser, P.C.
Selective C-KIT kinase inhibitor
The present invention provides a compound represented by formula (I), or a pharmaceutically acceptable salt, a solvate, an ester, an acid, a metabolite or a prodrug thereof. The compound itself in the present invention or in combination with at least one therapeutic agent can be used for preventing or treating diseases, disorders or symptoms caused by the adjustment of the activity of tyrosine kinase C-KIT, or affected by the activity of the tyrosine kinase C-KIT or involving in the activity of the tyrosine kinase C-KIT, especially cancers or other cell proliferation diseases.
HEFEI GRACEVO BIO-MEDICINE CO., LTD PRECEDO PHARMACEUTICALS CO., LTD
A A C A C A C C C A C C C
A61K A61K C07D A61P C07D A61K C07D C07D C07D A61K C07D C07D C07D
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Beilei Aoli Qiang Cheng Wei Fengming Chen Xiaochuan Tao Qingsong Wenchao Jing Ziping Zhenquan Li Feiyang Shuang
Wang Wang Wang Chen Wang Zou Hu Liu Ren Liu Wang Liu Qi Hu Wang Liu Qi