Muncy, Geissler, Olds & Lowe, PLLC
Method and apparatus for brain perfusion magnetic resonance images
The present invention discloses a method and apparatus for brain perfusion magnetic resonance imaging (MRI) technique with the removal of cerebrospinal fluid (CSF) pixels. This invention utilizes a CSF/brain-contrast-enhanced image, wherein the CSF/brain-contrast-enhanced image is defined as the signal difference between CSF and brain matter divided by a standard deviation of air background random noise is larger than 3, acquired from the subject's brain, and applies a segmentation technique to remove the CSF pixels. After removing the CSF pixels on parametric images, the extent of brain tissue with delayed perfusion can be better identified. By using a good region of interest enclosing the correct delayed-perfusion region, the measurement on the tissue volume and perfusion parameters would be more accurate than the area contaminated by CSF pixels.
National Yang-Ming University
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Mu-Huo Yu-Fen Wen-Yan Yi-Hsuan
Teng Chen Zheng Kao