Sterne, Kessler, Goldstein & Fox, P.L.L.C.
Anti-O1 antibodies and uses thereof
The present disclosure provides binding proteins (e.g., antibodies or antigen binding fragments thereof) that specifically bind to Klebsiella pneumoniae O1 and induce opsonophagocytic killing of Klebsiella (e.g., Klebsiella pneumoniae). The present disclosure also provides methods of reducing Klebsiella (e.g., Klebsiella pneumoniae) or treating or preventing Klebsiella (e.g., Klebsiella pneumoniae) infection in a subject comprising administering the Klebsiella pneumoniae O1 binding proteins, (e.g., antibodies or antigen-binding fragments thereof) to the subject.
MedImmune, LLC Humabs BioMed SA
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C12N C07K C07K C07K C07K G01N A61K A61K A61K A61K A61P C07K C07K C07K A61K G01N
inventional additional additional additional additional additional inventional additional additional inventional inventional inventional additional additional additional inventional
Davide Charles Jamese Meghan Martina Qun Chew-shun Gilad Xiaodong Elisabetta
Corti Stover Hilliard Pennini Beltramello Wang Chang Kaplan Xiao Cameroni