Winstead PC
Method for identification of low grade cervical cytology cases likely to progress to high grade/cancer
The present invention provides a method of using Raman spectroscopy for identification of low grade cervical cytology cases likely to progress to high grade/cancer. The Applicant has found that high quality Raman spectra can be successfully acquired from morphologically normal appearing cells from negative, LSIL and HSIL Thinprep® specimens and different grades of cervical pre-cancer can be separated with good sensitivities and specificities. Raman spectroscopy can further identify different categories of the LSIL cases i.e., whether they are likely to regress to negative or progress to HSIL cytology.
The Provost, Fellows, Foundation Scholars, and the Other Members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin Technological University Dublin
G G G G
G01N G01N G01J G01N
inventional inventional inventional inventional
Fiona John Shiyamala Cara Damien Padraig
Lyng O'Leary Duraipandian Martin Traynor Kearney