Townsend and Townsend and Crew LLP
Method of production of purified hepatitis a virus particles and vaccine preparation
The present invention provides methods of purification of Hepatitis A Virus from the supernatant of an infected cell culture and production of a preparation of purified HAV antigen. The present invention is also directed to an HAV vaccine composition comprising a preparation consisting of purified mature HAV particles in an amount sufficient to induce a protective immune response in a mammal.
Baxter Healthcare S.A.
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Y10S Y10S Y10S C12N Y10S A61K A61K A61P Y10S A61K Y02A A61P C12N A61K A61K C12N
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Christa Heidi Noel Artur
Tauer Meyer Barrett Mitterer