JHK Law
Peptides and derivatives thereof showing cell attachment, spreading and detachment activity
The present invention relates to peptides and derivatives thereof showing cell attachment, spreading and detachment activity. Particularly, the present invention relates to the peptide NKDIL and EPDIM and derivatives thereof which promote the cell attachment activity through interaction with a α 3β 1 integrin as a functional cell receptor and include aspartic acid and isoleucine essential for cell attachment and detachment activity. The peptides and derivatives thereof in the present invention can be used for developing a study of cell attachment activity mediated through various extracellular matrix protein containing β ig-h3, wound healing, tissue regeneration and metastasis inhibition.
Regen Biotech, Inc.
A A C C A A A C
A61P A61K C07K C07K A61P A61P A61P C07K
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Jung-Eun In-San
Kim Kim