AKC Patents, LLC
Voriconazole sodium phosphate hydrates and polymorphs thereof
The present invention relates to a voriconazole sodium phosphate hydrate, polymorphs thereof, a preparation method thereof, and use thereof, wherein the voriconazole phosphate salt hydrate prepared by using an isopropanol-water system, ethanol-water system, or an ethanol system comprises different crystal forms. And these kinds of crystal forms have favorable water solubility and stability and feature a simple manufacturing process. The voriconazole phosphate salt hydrate is principally used for treatment of fungal infections.
SHAANXI SYNTHETIC PHARMACEUTICAL Co., LTD.
C A
C07F A61P
inventional inventional
Qiyuan
Zhang