Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
Heterocyclic methyl sulfone derivative
Provided is a compound capable of inhibiting production or secretion of β amyloid protein.A compound represented by the following formula (1):(wherein, R1 represents a heterocyclic group which may have a substituent, R2 represents a cyclic hydrocarbon group which may have a substituent or a heterocyclic group which may have a substituent, R3 represents a cyclic hydrocarbon group which may have a substituent or a heterocyclic group which may have a substituent, R4 represents a hydrogen atom or a C1-6 alkyl group, and X represents —S—, —SO— or —SO2—); an N-oxide or S-oxide thereof; a salt thereof; or a solvate thereof; and a medicament containing any of them.
Daiichi Pharmaceutical Co., Ltd.
A A C A C C
A61P A61P C07D A61P C07C C07C
inventional inventional inventional inventional additional inventional
Kayoko Hideki Masanori Takanori Satoru Hitoshi
Motoki Kubota Saito Yasukouchi Miyauchi Iimori