Woodcock Washburn LLP
Piperidinyl and piperazinyl modulators of γ-secretase
The present invention relates to compounds of Formula I as shown below, wherein the definitions of Het, R0, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.
Janssen Pharmaceutica N.V. Cellzome Limited
C C C C C C A C A C
C07D C07D C07D C07D C07D C07D A61P C07D A61P C07D
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Yan Jeremy John Chih Yung Umar S. M.
Zhang Major Harrison Ho Maharoof