Bingham McCutchen LLP
On-spot hydrophilic enhanced slide and preparation thereof
The invention discloses an on-spot hydrophilic enhanced slide/microarray. The preparation method relates to a hydrophobic copolymer prepared by blending, grafting or co-polymerization of a hydrophobic material and a compound bearing functional groups such as anhydride, imide, cyclic amide, and cyclic ester, and application of the hydrophobic copolymer onto an organic or inorganic substrate. The resulting slide has the properties of on-spot hydrophilic/hydrophobic dynamic conversion, as well as on-spot hydrophilic enhancement for the preparation of high-density and high-efficiency bio-chip/microarray.
Industrial Technology Research Institute
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Yao-Sung Bor-Iuan Jia-Huey Wen-Hsun Chih-Wei Chao-Chi Zu-Sho Cheng-Tao Yu-Ching
Chang Jan Tsao Kuo Ho Pan Chow Wu Liu