Buchanan Ingersoll & Rooney PC
Derivatives of amanita toxins and their conjugation to a cell binding molecule
The present invention is related to novel cytotoxic agents, derivatives of Amanita toxins of Formula (I), wherein , -----, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, L, m, n and Q are defined herein, the preparation and the therapeutic uses in the targeted treatment of cancers, autoimmune disorders, and infectious diseases.
HANGZHOU DAC BIOTECH CO., LTD.
C A A A A A A A A A A A C Y A A
C07K A61P A61P A61P A61P A61P A61P A61P A61P A61P A61K A61P C07K Y02A A61P A61P
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Xiaomai Chengyu Chen Qingliang Hongsheng Shun Zixiang Hangbo Robert Yongxin Linyao Yuanyuan Junxiang Huihui Yifang Xiaotao Wenjun Minjun Qianqian
Zhou Yang Lin Yang Xie Gai Guo Ye Zhao Zhao Huang Jia Guo Xu Zuo Li Cao Tong