Fish & Richardson P.C.
Macrocyclic compounds as Trk kinase inhibitors
Compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein ring A, ring B, W, m, D, R2, R2a, R3, R3a, and Z are as defined herein, are inhibitors of Trk kinases and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
Array BioPharma Inc.
C A C C A A A C A A Y A A A A A C
C07D A61P C07D C07D A61K A61P A61P C07D A61P A61P Y02A A61P A61P A61P A61P A61P C07D
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional additional inventional inventional inventional inventional inventional inventional
Jeongbeob Yutong Gabrielle R. Qian Steven Wade HongWoon Kevin Ronald Julia
Seo Jiang Kolakowski Zhao Andrews Yang Condroski Haas