Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure:or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein W, L, R3, R3a, R3b and R4 are defined herein.
Bristol-Myers Squibb Company
A A A A A A A C A A A A
A61P A61P A61P A61P A61P A61P A61P C07D A61P A61P A61P A61P
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Lawrence G. Christopher B. Jeffrey A. Zheming Haixia James J. Jun
Hamann Cooper Robl Ruan Wang Li Li