Banner & Witcoff, Ltd.
Dihydropyrimidine compounds and preparation methods, pharmaceutical compositions and uses thereof
Disclosed are dihydropyrimidine compounds and preparation methods, pharmaceutical compositions and uses thereof. Specifically, the compounds described herein in general formula (I), or their isomers, pharmaceutically acceptable salts or hydrates are provided, wherein each variable has the meaning as defined in the description. Also provided are a process for preparing the compounds of the general formula (I), the use of the compounds, an isomer thereof, a pharmaceutically acceptable salt thereof or a hydrate thereof as a medicament, in particular as a medicament for the treatment and/or prevention of Hepatitis B.
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences, P.L.A. China
A A A A A C C C A C A C C
A61K A61P A61K A61K A61P C07D C07D C07D A61K C07D A61K C07D C07D
inventional inventional additional additional inventional inventional inventional inventional inventional inventional inventional additional inventional
Wu Lili Guoming Hongying Zhibing Junhai Yunde Hua Xiaoqian Xinbo Xiaokui Song Xingzhou
Zhong Wang Zhao Liu Zheng Xiao Xie Guan Xu Zhou Wang Li Li