Brinks Hofer Gilson & Lione
Antibodies against a secreted polypeptide that stimulates release of proteoglycans from cartilage
The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Genentech, Inc.
C C C
C07K C07H C07K
inventional inventional additional
J. Christopher Ellen Audrey William I. Austin L. Paul J.
Grimaldi Filvaroff Goddard Wood Gurney Godowski