Triazolyl PDE10 inhibitors
The present invention is directed to substituted triazolyl compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
Merck Sharp & Dohme Corp.
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Thomas Justin T. Carol A. Thomas Vadim Y. Scott D. Christopher D. June J.
Reger Sheen McVean Steele Dudkin Kuduk Cox Kim