Substituted pyrido[1,2-a]pyrazines as HIV integrase inhibitors
The present invention relates to 4-Pyridone Compounds of Formula (I); and pharmaceutically acceptable salts and prodrugs thereof, wherein A, R1, R2, and R3 are as defined herein. The present invention also relates to compositions comprising at least one 4-Pyridone Compound, and methods of using the 4-Pyridone Compounds for treating or preventing HIV infection in a subject or the clinical manifestations thereof.
Merck Sharp & Dohme Corp.
C C A A C A C C A
C07D C07D A61K A61K C07D A61P C07D C07D A61K
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Andrew Thomas H. John S. Wensheng
Stamford Graham Wai Liu