Burns, Doane, Swecker & Mathis, L.L.P.
Method for culturing microorganisms having a methanol metabolic pathway
 The present invention discloses a method for culturing microorganisms having a methanol metabolic pathway in which an expression unit is introduced that comprises a target gene linked downstream from a promoter that can be induced by methanol; wherein, during the culturing period, and including the period during which methanol is continuously or periodically added, the rate of addition is adjusted to a rate equal to or less than the maximum methanol consumption rate of said microorganisms. 
Suntory Limited
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inventional inventional
Nobuo Koji Tomohiro Yasuyoshi
Kato Magota Rogi Sakai