Bierman, Muserlian and Lucas
Process for producing desulfated polysaccharide, and desulfated heparin
 This invention relates to a process for producing a desulfated polysaccharide, which comprises reacting a sulfated polysaccharide having a saccharide in which a primary hydroxyl group is sulfated, as a constituent sugar, with a silylating agent represented by the following formula (I) ##STR1## wherein R.sup.1 s are the same or different and each represent a hydrogen atom or a halogen atom, R.sup.2 represents a lower alkyl group, and R.sup.3 s are the same or different and each represent a lower alkyl group, an aryl group or a halogen atom, and a desulfated heparin obtained by this production process. 
Seikagaku Corporation
A C A A A C
A61K C08B A61P A61P A61P C08B
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Keiichi Saburo Masayuki
Yoshida Hara Ishihara