Fitzpatrick, Cella, Harper & Scinto
Polymer, contrast agent for nuclear magnetic resonance analysis or magnetic resonance imaging using the polymer, compound and method of nuclear magnetic resonance analysis and method of magnetic resonance imaging using the polymer
As a substance used as a contrast agent for a method of nuclear magnetic resonance analysis or a method of magnetic resonance imaging, a substance with high selectivity and high sensitivity was demanded. According to the present invention, when a polymer having, in a side chain thereof, a sequence of a 1H—13C—15N, 1H—15N—13C or 1H—13C—13C bond, that is, a structure labeled with stable isotopes of 13C and 15N, is used, the abundance of such a sequence in one molecule can be increased, and hence, high selectivity and higher sensitivity can be attained when used as a contrast agent.
CANON KABUSHIKI KAISHA
C A A
C08F A61K A61K
inventional inventional inventional
Yasuhiro Fumio Hidehito Yu Teruyuki Hisatsugu Masahiro Tetsuya Hidetoshi Masato Shinsuke Yoshinori Fuminori Tetsuya
Aoyama Yamauchi Tochio Kimura Kondo Yamada Shirakawa Yano Tsuzuki Minami Sando Hasegawa Sugihara Matsuda