Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
Cyclic hexapeptides with antimicrobial activity
 This invention relates to new polypeptide compounds represented by general formula (I), wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on .beta.-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal. ##STR1## 
Fujisawa Pharmaceutical Co., Ltd.
A A A A A C
A61K A61P A61P A61P A61P C07K
additional inventional inventional inventional inventional inventional
Kenji David Takahiro Hiroshi Nobuyuki Kohji Hidenori Hiroaki Keiji Takashi
Murano Barrett Matsuya Matsuda Shiraishi Kawabata Ohki Mizuno Matsuda Tojo