Modulators of ATP-binding cassette transporters
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Vertex Pharmaceuticals Incorporated
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Sarah S. Peter D. J. Ashavini K. Anna Ruth Matthew Lewis R. Liming Mark T.
Hadida Ruah Grootenhuis Singh Hazlewood Hamilton Makings Huang Miller