Marquez IP Law Office, PLLC
Method for prolonging the over survival of a cancer patient
The present invention relates to a method for treating a cancer with the combination of a topoisomerase II inhibitor (TOP2 inhibitor) and a histone deacetylation inhibitor (HDACi), provides synergistic cancer cell-killing effects, and prolonged overall survival, especially when the expression of checkpoint kinase 1 (CHK-1) is low.
National Yang-Ming University
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Jin-Hwang
Liu