Benzodioxane inhibitors of leukotriene production
The present invention relates to compounds of formula (I):wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
Boehringer Ingelheim International GmbH
C A A C C C C A C C A C A A C A A A A C C A A A C A A C
C07D A61P A61P C07D C07D C07D C07D A61P C07D C07D A61P C07D A61P A61P C07D A61K A61P A61K A61P C07D C07D A61P A61P A61P C07D A61P A61P C07D
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Qiang Asitha Anil Kumar Hidenori Michael J. Qing Michael Robert Thomas Martin Lana Louise Matthew Russell
Zhang Abeywardane Padyana Takahashi Burke Zhang Turner Kirrane, Jr. Smith Keenan Netherton