Marshall, Gerstein & Borun LLP
Binding molecule specific for Lrig-1 protein and use thereof
The present invention relates to a binding molecule capable of specifically binding to Lrig-1 protein, which is on the surface of regulatory T cells. The binding molecule provided in the present invention can suppress the function of regulatory T cells to effectively prevent, ameliorate, or treat cancer, particularly solid tumor. The binding molecule has advantages of more effectively targeting the Lrig-1 protein as compared with antibodies against Lrig-1 which are previously commercially available, and also possessing very good binding capacity thereto.
GOOD T CELLS, INC.
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Jung Ho Beom Seok
Kim Kim