Polynucleotides encoding a novel metalloprotease, MP-1
The present invention provides novel polynucleotides encoding MP-1 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MP-1 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
Bristol-Meyers Squibb Company
C C
C07K C12N
additional inventional
Stanley R. John N. Thomas C. Jian Franck
Krystek Feder Nelson Chen Duclos