Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
Pyrazinyl hydroxyacrylamide compounds having an inhibitory effect on the activity of histone deacetylase
This invention relates to novel N-hydroxyacrylamide compounds of formula (I) and pharmaceutically acceptable salts thereof. More particularly, it relates to novel N-hydroxyacrylamide compounds and pharmaceutically acceptable salts thereof which act as a HDAC inhibitor, to a pharmaceutical composition comprising the same and to a method of using the same therapeutically in the treatment and/or prevention of HDAC-related disease.
Astellas Pharma Inc.
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inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Yoshiteru Fumiyuki Hiromichi Yoshihiro Hideo Taro
Eikyu Shirai Itani Kozuki Tsutsumi Masunaga