Polsinelli PC
Generation of antibodies to tumor antigens and generation of tumor specific complement dependent cytotoxicity by administration of oncolytic vaccinia virus
The present invention relates to methods and compositions for use in inducing tumor-specific antibody mediated complement-dependent cytotoxic response in an animal having a tumor comprising administering to said animal a composition comprising a replication competent oncolytic virus wherein administration of the composition induces in the animal production of antibodies that mediate a CDC response specific to said tumor.
SILLAJEN, INC SILLAJEN BIOTHERAPEUTICS, INC.
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John Caroline Mi-kyung Yu Kyoung Tae-Ho Anne David
Bell Breitbach Kim Lee Hwang Moon Kirn