Nath, Goldberg & Meyer
3′,4′,5-trimethoxy flavone derivatives as stimulant of mucus secretion, method for the same, and pharmaceutical composition comprising the same
The present invention provides a 3′,4′,5-trimethoxy flavone derivative and a pharmaceutically acceptable salt thereof, preparation thereof, and a pharmaceutical composition for the treatment and prevention of dry eye syndrome comprising the same as an active ingredient.The 3′,4′,5-trimethoxy flavone derivative and its pharmaceutically acceptable salt inhibit corneal damage through excellent stimulatory action on mucus secretion in the conjunctiva and therefore may be effective as a prophylactic or therapeutic agent for dry eye syndrome.
Dong-A Pharm. Co., Ltd.
C A C
C07D A61P C07D
inventional inventional inventional
Moo-Hi Kyung-Koo Mi-Jeong Ju-Mi Dong-Sung Jeong-Hoon Yong-Duck Seul-Min Sun-Woo Byoung-Ok Yong-Sung
Yoo Kang Seo Kim Kim Kim Kim Choi Jang Ahn Shon