Substituted 4-aminoquinoline derivatives as gastric secretion inhibitors
 Substituted 4-aminoquinazoline derivatives of the formula: ##STR1## wherein R.sup.1 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-6 alkoxy C.sub.1-6 alkyl, PA1 C.sub.3-6 cycloalkyl, C.sub.3-6 cycloalkyl C.sub.1-6 alkyl, phenyl C.sub.1-6 alkyl, the phenyl group being optionally substituted; PA1 R.sup.2 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, amino, C.sub.1-6 alkylthio, halogen, cyano, hydroxy, C.sub.1-6 alkanoyl or trifuromethyl; PA1 m is 1 to 3; PA1 R.sup.3 is hydrogen, C.sub.1-6 alkyl, phenyl, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio, C.sub.1-6 alkanoyl, amino, C.sub.1-6 alkylamino, ci-C.sub.1-6 alkylamino, halogen, trifluoromethyl or cyano; PA1 n is 1 or 2; and PA1 R.sup.4 is hydrogen; or a salt thereof are useful as inhibitors of gastric acid secretion. 
SmithKline Beckman Intercredit B.V.
C C A A
C07D C07D A61P A61P
inventional inventional inventional inventional
Robert J. Colin A. Thomas H.
Ife Leach Brown