Sughrue, Mion, Zinn, Macpeak & Seas, PLLC
3,4-disubstituted phenylethanolaminotetralincarboxamide derivatives
 The present invention relates to 3,4-disubstituted phenylethanolaminotetralincarboxamide derivatives represented by the general formula: ##STR1## (wherein A represents a lower alkylene group; B represents an amino group, a di(lower alkyl)amino group or a 3 to 7-membered alicyclic amino group which may contain an oxygen atom in the ring; n is an integer of 1 or 2; the carbon atom marked with * represents a carbon atom in R configuration, S configuration or a mixture thereof; and the carbon atom marked with (S) represents a carbon atom in S configuration) and pharmaceutically acceptable salts thereof, which have a selective .beta..sub.2 -adrenergic receptor stimulating effect with relieved burdens on the heart such as tachycardia and are useful as an agent for the prevention of threatened abortion and premature labor, a bronchodilator and an agent for pain remission and stone removal in urolithiasis. 
Kissei Pharmaceutical Co., Ltd.
A A A C C A C A A
A61P A61P A61P C07C C07C A61P C07D A61P A61P
inventional inventional inventional inventional additional inventional inventional inventional inventional
Hideyuki Hiroaki Tetsuro Nobuyuki Kosuke Makio Ken Masaru
Muranaka Kobayashi Tamai Tanaka Okazaki Kitazawa Kikuchi Saito