Spiroxazolidinone compounds
Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, Metabolic Syndrome, depression, and anxiety.
Merck Sharp & Dohme Corp.
A A A C C
A61P A61P A61P C07D C07D
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Remond Harold B. Paul E. Edward C. Michael A. Sriram Feng Patrick Weiguo Feroze F. Anthony Yi Zahid Debra L. Joseph L. Jianming Aaron Revathi
Moningka Wood Finke Sherer Plotkin Tyagarajan Ye Shao Liu Ujjainwalla Romero Zang Hussain Ondeyka Duffy Bao Zwicker Katipally