Kilpatrick Townsend & Stockton LLP
CD127 expression inversely correlates with FoxP3 and suppressive function of CD4+ tregs
The invention provides methods of isolating CD127lo/− immunosuppressive regulatory T cells which can be greatly enriched for FoxP3, methods of expanding the isolated cells, pharmaceutical compositions of such cells, and methods of their use in the treatment of autoimmune and other immune system mediated disorders.
The Regents of the University of California
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Weihong Jeffrey A. Amy
Liu Bluestone Putnam