Leydig, Voit & Mayer, Ltd.
Glycosylation-resistant cyanovirins and related conjugates, compositions, nucleic acids, vectors, host cells, methods of production and methods of using nonglycosylated cyanovirins
The invention provides a method of inhibiting prophylactically or therapeutically an influenza viral infection in a host. The method comprises instilling into or onto a host a cell producing an antiviral protein, antiviral peptide, or antiviral conjugate comprising at least nine contiguous amino acids of SEQ ID NO: 2, wherein the at least nine contiguous amino acids are nonglycosylated and have antiviral activity, whereupon the influenza viral infection is inhibited.
The United States of America as represented by the Department of Health and Human Services
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A61P A61P A61P C07K Y10S A61K
inventional inventional inventional inventional additional additional
Michael R. Angela M. Barry R. Toshiyuki
Boyd Gronenborn O'Keefe Mori