Osha • Liang LLP
Pyridyl derivatives and their use as therapeutic agents
Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I): wherein W, V, x, y, R1, R2, R3, R4, R5, R6, R7, R7a, R8, R8a, R9, R9a, R10 and R10a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Xenon Pharmaceuticals Inc.
C A A C A A C A A A A A A A A A A C C A A A
C07D A61P A61P C07D A61P A61P C07D A61P A61P A61P A61K A61P A61K A61P A61P A61K A61P C07D C07D A61P A61P A61P
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Vishnumurthy Serguei Daniel F. Michael D. Shaoyi Heinz W. Wenbao Melwyn Rajender Shifeng Mikhail A. Nagasree
Kodumuru Sviridov Harvey Winther Sun Gschwend Li Abreo Kamboj Liu Kondratenko Chakka