Method of preparing 6-chloro-5-nitro-2,4-diaminopyrimidine and its application thereof
A method of preparing 6-chloro-5-nitro-2,4-diaminopyrimidine includes: reacting guanidine hydrochloride with ethyl carbamoylacetate and sodium hypochlorite in the presence of a metal nitrate salt and acetate anhydride in an organic solvent.
XI'AN TAIKOMED PHARMACEUTICAL TECHNOLOGY CO., LTD.
C C A
C07D C07B A61P
inventional additional inventional
Juan Chengyuan Han Xuechuan Yonghong Minghui Danni Kaiqi
Xia Liang Li Wang Tang Chang Tian Shi