Heslin Rothenberg Farley & Mesiti P.C.
Complex of bifunctional chelating agent and mannosyl human serum albumin
The present invention is about bifunctional chelating agents (BCA) conjugated mannosyl human serum albumin (MSA) and its radioisotope labeled compounds for imaging immune system such as macrophages, Kupffer cells, reticuloendothelial system (RES), and lymphatic system. The present invention comprises BCA-MSA conjugates, their radiolabeled compounds, and kits for radiolabeing. The present invention improved radiolabeling procedure, showed higher lymphatic system uptake, and enabled image by positron emission tomography (PET).
SNU R&DB Foundation
A A A
A61K A61K A61P
inventional inventional inventional
Myung Chul Jae Min June Key Dong Soo
Lee Jeong Chung Lee