McDonnell Boehnen Hulbert & Berghoff
Canine allergy therapeutic recombinant chimeric anti-IgE monoclonal antibody
The present invention provides methods and compositions for decreasing IgE levels in dogs. The methods and compositions are useful for treating allergic symptoms in dogs. The invention may comprise chimeric canine anti-IgE monoclonal antibody compositions and methods for using the compositions in the treatment of allergy. In preferred embodiments, the compositions of the present invention may act by binding soluble IgE in plasma, or by inhibiting IgE from binding to receptors on mast cells, B cells, and basophils.
Idexx Laboratories, Inc.
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Hongliang Eugene R. Wendy W. Brion Robert L. Ashok P.
Guo Krah, III Liu Mermer Lawton Aiyappa