McCarter & English, LLP
Isoindoline inhibitors of ROR-gamma
Provided are novel compounds of Formula (I):pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORγ. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.
Vitae Pharmaceuticals, Inc.
C C C C C
C07D C07D C07D C07D C07D
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Stephen D. Suresh B. Jing Yi Colin M. Yajun Wei Linghang Chengguo David A. Lanqi Lawrence Wayne Andrew
Lotesta Singh Yuan Fan Tice Zheng Zhao Zhuang Dong Claremon Jia Dillard Marcus