Norton Rose Fulbright Canada LLP
Catalyst-free and redox-neutral innate trifluoromethylation and alkylation of (hetero)aromatics enabled by light
The present disclosure relates to reagents and method for performing trifluoromethylation, difluoromethylation or alkylation of aromatic or heteroaromatic rings in a redox-neutral manner without any catalyst which are enabled by light. In addition, there are methods for synthesizing the starting reagents used in the trifluoromethylation, difluoromethylation or alkylation reactions.
THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
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Wenbo Chao-Jun Peng
Liu Li Liu