Banner & Witcoff, Ltd.
Aromatic butan-2-ol compounds and preparation and uses thereof
Aromatic butan-2-ol compounds, preparation methods for making the compounds, and uses of the compounds are provided. Specifically, the compound of Formula I, or an optical isomer, racemate, diastereomer, pharmaceutically acceptable salt, or solvate thereof, is provided, where each of the substituents is defined. In addition, a pharmaceutical composition containing the compound, and the use of the compound in manufacture of a medicament for the treatment and/or prophylaxis of a disease or disorder caused by tubercle bacillus infection, is provided.
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
C A A C C
C07C A61K A61P C07C C07C
inventional inventional inventional inventional inventional
Junhai Yunde Xinbo Lili Wu Xiaokui Ping Xingzhou Song Zhibing Guoming
Xiao Xie Zhou Wang Zhong Wang Liu Li Li Zheng Zhao