Compounds for the treatment of inflammatory disorders
This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
Merck Sharp & Dohme Corp.
A C A A C A C C
A61P C07D A61P A61P C07D A61P C07D C07D
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Guowei Judson E. De-Yi Luke Wensheng Aneta Maria Seong Heon Bandarpalle B. Kristen E. Joseph A. Razia K. Lei Ling Brian J. Dansu Michael K. C.
Zhou Richard Yang Fire Yu Kosinski Kim Shankar Rosner Kozlowski Rizvi Chen Tong Lavey Li Wong