Thiazole-amine compounds for the treatment of neurodegenerative disorders
The present invention relates to compounds of the Formula Iwherein R1, R3, R4, R5, R6 and R7 are as defined. Compounds of the Formula I have activity inhibiting production of Aβ-peptide. The invention also relates to pharmaceutical compositions and methods of treating disorders and diseases, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
Pfizer Inc.
A A A A A A A A A A C C A A A A A
A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C07D C07D A61P A61P A61P A61P A61P
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Yuhpyng L.
Chen