Spirocyclic Pyridotriazine Derivatives useful as HIV integrase inhibitors
The present invention relates to Spirocyclic Pyridotriazine Derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, B, X, Y, R1, R2 and R10 are as defined herein. The present invention also relates to compositions comprising at least one Spirocyclic Pyridotriazine Derivative, and methods of using the Spirocyclic Pyridotriazine Derivatives for treating or preventing HIV infection in a subject.
Merck Sharp & Dohme Corp.
A C A A A A A C
A61K C07F A61K A61K A61K A61P A61K C07D
inventional inventional additional additional additional inventional additional inventional
Andrew Tao John A. Wengsheng Libo Sherman T. Jay A. Thomas H.
Stamford Yu McCauley Liu Xu Waddell Grobler Graham