Compounds useful as reversible inhibitors of cysteine proteases
Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formula (Ia) and (Ib) where R2, R3, R4, R5, R6, R7, R8, Het and X are defined herein. The compounds are useful for treating autoimmune and other diseases. Also disclosed are processes for making such novel compounds.
Boehringer Ingelheim Pharmaceuticals, Inc.
C A A C C C C A C C A C A C C A A C C A A A C C A C C C C
C07D A61P A61P C07D C07D C07D C07D A61P C07D C07D A61P C04B A61P C07D C07D A61P A61P C07D C07D A61P A61P A61P C07D C07D A61P C07D C07D C07D C07D
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Eugene R. Weimin Erick R. R. Younes Yancey D. Denice M. David S. Sanxing Usha R.
Hickey Liu Young Bekkali Ward Spero Thomson Sun Patel