McDermott Will Emery LLP
Monoclonal antibody which specifically recognizes B cell lymphoma and use thereof
Provided is a monoclonal antibody which specifically recognizes B cell lymphoma cells and a use thereof. More specifically, provided are the monoclonal antibody; a pharmaceutical composition for preventing or treating B cell lymphoma including the monoclonal antibody; a composition for diagnosing B cell lymphoma including the monoclonal antibody; a method for providing information for diagnosing B cell lymphoma using the monoclonal antibody; a chimeric antigen receptor (CAR) protein including i) the antibody, ii) a transmembrane domain, and iii) an intracellular signaling domain; a recombinant vector which expresses the CAR protein; a CAR-modified T cell transformed with the recombinant vector; a pharmaceutical composition for preventing or treating B cell lymphoma including the CAR-modified T cell; and an antibody-drug conjugate wherein the monoclonal antibody and a drug are conjugated.
Eutilex Co., Ltd.
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G01N C07K C07K A61K A61K C07K A61K C07K C07K C07K C07K G01N C07K
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Seung-Joo Ho-Sik Byoung Se Insoo Chungyong Kwang-Hui Beom-Kyu Don-Gil Young-Ho
Lee Oh Kwon Park Han Kim Choi Lee Kim