Substituted 6-azabenzimidazole compounds
The present disclosure relates generally to certain 6-azabenzimidazole compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.
Gilead Sciences, Inc.
C C A
C07D C07D A61P
inventional inventional inventional
Rao V. Zachary A. Seung H. Patrick J. Jeff Jennifer A. Jennifer R. Jennifer L. Joshua J. Gary B. Sundaramoorthi Mark J. Suet C. Thao D. Gayatri Scott A. John H. Musong Jayaraman Julian A.
Kalla Kasun Lee Salvo Zablocki Loyer-Drew Lo Cosman Van Veldhuizen Phillips Swaminathan Bartlett Yeung Perry Balan Mitchell Conway Kim Chandrasekhar Codelli