McCarter & English, LLP
Substituted indoles as modulators of ROR-gamma
Provided are novel compounds of Formula I: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions comprising the novel compounds of Formula I and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.
Vitae Pharmaceuticals, LLC
A C A C C C C C C C C A C C A A A A A A C
A61P C07D A61P C07D C07B C07D C07D C07D C07D C07D C07D A61P C07D C07D A61P A61P A61P A61P A61P A61P C07B
inventional inventional inventional inventional additional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional additional
Stephen D. Wei Colin M. Linghang David A. Lawrence Wayne Yi Suresh B.
Lotesta Zhao Tice Zhuang Claremon Dillard Fan Singh