Leydig, Voit & Mayer, Ltd.
Fusion protein comprising anti-c-Met antibody and VEGF-binding fragment
There are provided a fusion protein formed by coupling of anti-c-Met antibody and VEGF-binding fragment, a bispecific antibody comprising the fusion protein, a polynucleotide encoding the fusion protein, a transformant comprising the polynucleotide, a pharmaceutical composition comprising the bispecific antibody as an active ingredient, and a method for preparing the bispecific antibody which is targeted at c-Met and VEGF at the same time, with improved anticancer and anti-angiogenesis effects, comprising coupling an anti-c-Met antibody with a VEGF-binding fragment.
SAMSUNG ELECTRONICS CO., LTD.
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A61P C07K C07K C07K C07K C07K C07K A61P C07K C07K C07K C07K C07K A61P A61P C07K C07K C07K A61P A61K
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Ho Yeong Kyung Ah Yun Ju Seung Hyun Yun Jeong
Song Kim Jeong Lee Song