Beveridge, DeGrandi & Weilacher
6-Amidino-2-naphthyl 4-guanidinobenzoate derivatives and pharmaceutical composition containing them
 Amidine compounds of formula (I) ##STR1## and the pharmaceutically acceptable acid addition salts thereof are novel and are of use as anti-trypsin, anti-plasmin, anti-kallikrein, anti-thrombin and anti-complement agents which may be administered orally. These amidine compounds can be produced by the reaction between a carboxylic acid compound of formula (II) ##STR2## or a reactive intermediate thereof and 6-amidino-2-naphthol of formula (III) ##STR3## or preferably an acid addition salt thereof. 
Torii & Co., Ltd.
A A C A C A A C A C
A61P A61P C07D A61P C07D A61P A61P C07D A61P C07C
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Masateru Toyoo Shinichi Kimio Takuo Toshiyuki Shigeki Setsurou
Kurumi Nakayama Watanabe Sudo Aoyama Okutome Nunomura Fujii