Simultaneous estimation of respiratory mechanics and patient effort via parametric optimization
Respiratory variables are estimated on a per-breath basis from airway pressure and flow data acquired by airway pressure and flow sensors (20, 22). A breath detector (28) detects a breath interval. A per-breath respiratory variables estimator (30) fits the airway pressure and flow data over the detected breath interval to an equation of motion of the lungs relating airway pressure, airway flow, and a single-breath parameterized respiratory muscle pressure profile (40, 42) to generate optimized parameter values for the single-breath parameterized respiratory muscle pressure profile. Respiratory muscle pressure is estimated as a function of time over the detected breath interval as the single-breath parameterized respiratory muscle pressure profile with the optimized parameter values, and may for example be displayed as a trend line on a display device (26, 36) or integrated (32) to generate Work of Breathing (WoB) for use in adjusting settings of a ventilator (10).
Koninklijke Philips N.V.
A A G A G A G A A A G A A
A61B A61B G16H A61B G16H A61B G16H A61B A61B A61B G16H A61B A61B
additional inventional inventional inventional inventional additional additional inventional inventional inventional inventional inventional inventional
Dong Nicolas Wadih Nikolaos Francesco Antonio
Wang Chbat Karamolegkos Vicario Albanese