Scully, Scott, Murphy & Presser, P.C.
Inhibitor of FLT3 kinase and use thereof
The present invention provides a novel inhibitor of FLT3 kinase, comprising a compound of formula (I) or a pharmaceutically acceptable salt, solvate, isomer, ester, acid, metabolite or prodrug thereof. The present invention also provides a pharmaceutical composition comprising the compound of formula (I), as well as the use and method for preventing or treating FLT3-related conditions, especially conditions related to mutant FLT3 kinase (particularly, FLT3/ITD mutant kinase).
PRECEDO PHARMACEUTICALS CO., LTD
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A61P A61P A61P C07D A61P A61K
inventional inventional inventional inventional inventional additional
Chen Ziping Jiaxin Aoli Jing Xixiang Wenchao Qingsong Cheng Hong Li Beilei
Hu Qi Wu Wang Liu Li Wang Liu Chen Wu Wang Wang