Fish & Richardson P.C.
Aminopyrazole derivative
A method for treating cancer that includes administering a pharmaceutically effective amount of a composition containing a compound represented by formula (I) or a pharmacologically acceptable salt thereof. In the formula, A represents a 5- to 10-membered heteroaryl group, or a C6-10 aryl group; R1 and R2 independently represent H, OH, X, CN, NO2, a C1-4 haloalkyl group, a C1-6 alkyl group, or the like <R1 and R2 together form a (substituted) 3- to 10-membered heterocyclyl group or a (substituted) 5- to 10-membered heteroaryl group>; R3 represents H, a C1-5 alkyl group, a C6-10 aryl group, a C1-5 alkyl group, or a C1-4 haloalkyl group; and R4 represents H, X, a C1-3 alkyl group, a C1-4 haloalkyl group, OH, CN, NO2, or the like.
Chugai Seiyaku Kabushiki Kaisha F. Hoffmann-La Roche AG
A A A A C C C A A C C C A C A A C A A A
A61P A61K A61K A61K C07D C07D C07D A61K A61K C07D C07D C07F A61K C07D A61K A61P C07D A61P A61K A61K
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Naoki Masami Ikumi Toshiyuki Masayuki Tadakatsu Lisha Hirosato Hiroki Yoshito Masayuki Kyoko Weili
Taka Kochi Hyodo Mio Matsushita Hayase Wang Ebiike Nishii Nakanishi Ohmori Takami Zhao