Mintz, Levin, Cohn, Ferris, Glovsky & Popeo, P.C.
Small molecule modulators of pantothenate kinases
The present disclosure relates to chemical compounds that modulate pantothenate kinase (PanK) activity for the treatment of metabolic disorders (such as diabetes mellitus type II), neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC.
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Richard E. Suzanne Chitra Charles O. Mi Kyung Lalit Kumar Jiuyu
Lee Jackowski Subramanian Rock Yun Sharma Liu