Millen, White, Zelano and Branigan
Stable aqueous preparation
 Presented is a stable aqueous preparation for ophthalmic topical administration containing vitamin A or a vitamin A derivative having vitamin A activities to be used for the treatment of dry eye syndrome characterized in that it contains a buffering component selected from the group consisting of phosphoric acid, boric acid, citric acid, glutamic acid, .epsilon.-aminocaproic acid and the alkali metal salts thereof, a non-ionic surfactant and a chelating agent, that its acidity is adjusted in the range of pH 5 to pH 8, and that it is filled in a tight container made of polypropylene or polyethylene terephthalate. 
Senju Pharmaceutical Company, Limited
A A A
A61P A61K A61K
inventional inventional inventional
Kenichi Kazumichi
Yoshida Ushio