Harness, Dickey & Pierce, P.L.C.
Pharmaceutical composition with enhanced efficacy for inhibiting angiogenesis
The present invention relates to a pharmaceutical composition for inhibiting angiogenesis and a novel sulfonyl amide derivative compound which can be useful for the prevention or treatment of angiogenesis-related diseases or disorders. Since the compound used as an active ingredient in the pharmaceutical composition of the invention is specifically bound to UQCRB and inhibits biological functions thereof, apoptosis is not induced and angiogenic responses are inhibited. Therefore, the compound used as an active ingredient in the pharmaceutical composition of the invention can be useful as an effective and safe angiogenesis inhibitory agent.
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
A C C A C C
A61P C07C C07D A61P C07C C07C
inventional additional inventional inventional inventional inventional
Gyoon Hee Ho Jeong Hye Jin Jeong Jea
Han Kwon Jung Seo