Rimon, P.C.
Pharmaceutical salts, physical forms, and compositions of pyrrolopyrimidine kinase inhibitors, and methods of making same
Provided are methods of making certain pyrrolopyrimidine derivatives, which are useful in the treatment of proliferation disorders and other diseases related to the dysregulation of kinase (such as, but not limited to, EGFR (including HER), Alk, PDGFR, BLK, BMX/ETK, BTK, FLT3 (D835Y), ITK, JAK1, JAK2, JAK3, TEC and TXK) and/or the respective pathways, salts, polymorphs, and amorphous forms of said compounds, synthetic intermediates for preparing said compounds, and pharmaceutical compositions comprising said compounds and methods for making such compositions.
ACEA THERAPEUTICS, INC.
A A A A C A A A C
A61K A61P A61K A61K C07B A61P A61K A61P C07D
inventional inventional inventional inventional additional inventional inventional inventional inventional
Bojie Xiaopeng Yimei Yile Jia Kongen Xiaobo Wanhong Jian Xiao Yuning Long
Weng Mo Bao Chen Liu Dai Wang Xu Wu Xu Hua Mao