Total synthesis of taxol and taxol analogs
 The total synthesis of taxol employs a convergent synthetic plan. The synthetic plan may also be employed to produce a large number of taxol analogs. Taxol analogs having skeletal extensions are inaccessible by modification of the natural product but are readily produced by employing the convergent synthetic plan herein. 
The Scripps Research Institute
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K. C. Zhen Philippe G. Hiroaki Jin-Jun
Nicolaou Yang Nantermet Ueno Liu