McCarter & English, LLP
Camptothecin derivatives
Disclosed herein are novel cytotoxic compounds, and cytotoxic conjugates comprising these cytotoxic compounds and cell-binding agents. More specifically, this disclosure relates to novel camptothecin derivatives thereof, intermediates thereof, conjugates thereof, and pharmaceutically acceptable salts thereof, which are useful as medicaments, in particular as anti-proliferative agents (anticancer agents).
IMMUNOGEN, INC.
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A61K A61P A61K C07D A61K A61K A61K A61K
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Wayne C. Wei Ravi V. J. David P.
Widdison Li Chari Pleynet