Covalent oligonucleotide-horseradish peroxidase conjugate
 Oligonucleotides derivatized to incorporate horseradish peroxidase (HRP) are useful in diagnostic methods and provide significant advantage over radioactively labeled oligonucleotide probes. The HRP-derivatized oligonucleotides can be easily and efficiently prepared by reacting a sulfhydryl containing oligonucleotide with a conjugate of a mal-sac-HNSA ester and HRP under mild and easily controlled reaction conditions. 
Cetus Corporation
Y C
Y10S C07H
additional inventional
Chu-an Fred T. Corey
Chang Oakes Levenson