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Amorphous asiatic tromethamine salt and preparation method thereof
An amorphous asiatic tromethamine salt and the preparation method thereof. The method includes the steps of: (1) dissolving asiatic acid in an organic solvent; step (2) mixing with tromethamine; step (3) stirring and salifying the same, and then removing the organic solvent. The method for preparing the amorphous asiatic tromethamine salt is easy and effective, and the water solubility and bioavailability of the asiatic tromethamine salt thus obtained are greatly compared with the prior art.
Shanghai Institute of Pharmaceutical Industry
C C C C
C07C C07C C07J C07C
inventional inventional inventional inventional
Zhen Yifang Liling Li Yan Guobin Minyu Renhai Chungang Lin Ying Haiyan Xiaoling Xiangduan Zhiru Xuejun Quanhai Jinyao
Zhang Deng Jin Cai Qin Ren Liu Chen Li Xiao Liu Sun Huang Tan Xu Wu Liu Chen