Substituted bicyclic amines for the treatment of diabetes
Described herein are substituted bicyclic amines. In particular, described herein are substituted bicyclic amines that are effective as antagonists of SSTR5 and useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, metabolic syndrome, depression, and anxiety.
Merck Sharp & Dohme Corp.
A C C A A A C C A C A
A61P C07D C07D A61P A61P A61P C07D C07D A61P C07D A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Gui-Bai Jiafang Weiguo John Lihu
Liang He Liu Bawiec Yang