Clark & Elbing LLP
Chemical and method for analyzing DNA sequence by visualizing single-molecule DNA and use thereof
The present disclosure relates to a composition for analysis of DNA sequences and a method for analysis of DNA sequences by using the same and, more particularly, to a composition comprising the compound represented by Chemical Formula 1 and a method for analysis of DNA sequences, the method comprising a step of treating a sample with the same. The compound represented by Chemical Formula 1 in which TAMRA is linked to polypyrrole specifically binds an A/T base pair (W) to fluoresce alone without causing DNA photocleavage. Therefore, the compound is useful for DNA analysis particularly at the single DNA molecule level.
Sogang University Research Foundation
C C C C
C12Q C12Q C12Q C07D
inventional inventional additional inventional
Kyu Bong Hiroshi Seong Hyun
Jo Sugiyama Lee