McDermott Will & Emery LLP
Alpha-helix analog having triazine-piperazine backbone and method for preparing same
The alpha-helix mimetic containing a triazine-piperazine scaffold is provided. The alpha-helix mimetic compound can mimic efficiently the alpha-helix structure of protein secondary structure and act as an inhibitor for the protein interaction being specific to various diseases mediated by alpha-helix. Therefore, the compound can be used as a biological probe and have a high potential of drug treating diseases.
POSTECH ACADEMY-INDUSTRY FOUNDATION POSCO
C A A C A A C A
C07D A61K A61P C07D A61P A61P C07D A61K
inventional inventional inventional inventional inventional inventional inventional inventional
Hyun-Suk Misook Wei Quyen Q.
Lim Oh Wang Hoang