ERK inhibitors
The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and a pharmaceutically acceptable carrier. The invention also provides a pharmaceutical composition comprising an effective amount of at least one compound of Formula (I) and an effective amount of at least one other pharmaceutically active ingredient (such as, for example, a chemotherapeutic agent), and a pharmaceutically acceptable carrier.
MERCK SHARP & DOHME CORP.
A C C A A A
A61K C07D C07D A61K A61K A61P
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Jongwon Wei Raman Kumar Kathryn Ann David Hua Xianhai David Ziping Phieng Joey Danielle David L. Jianmin Christopher Ganesh Babu Zhilong
Lim Liu Bakshi Lipford Witter Zhou Huang Guerin Liu Siliphaivanh Methot Molinari Sloman Fu Boyce Karunakaran Wan