Compounds useful as reversible inhibitors of cysteine proteases
Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formula (Ia) and (Ib) where R2, R3, R4, R5, R6, R7, R8, Het and X are defined herein. The compounds are useful for treating autoimmune and other diseases. Also disclosed are processes for making such novel compounds. 
Boehringer Ingelheim Pharmaceuticals, Inc.
A C A C C C C A A C C C A C C A C C A C C C C A C A C A A
A61P C07D A61P C07D C07D C07D C07D A61P A61P C04B C07D C07D A61P C07D C07D A61P C07D C07D A61P C07D C07D C07D C07D A61P C07D A61P C07D A61P A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Weimin Denice M. Erick R. R. Yancey D. David S.
Liu Spero Young Ward Thomson