Sughrue Mion, PLLC
Pharmaceutical compound comprising a pyrazole derivative and methods of using the same for the treatment of calcium release-activated calcium channel associated diseases
The present invention is directed to drugs, in particular, pyrazole derivatives represented by the following general formula (I) which have a calcium release-activated calcium channel inhibitory effect and medicinal compositions, in particular, calcium release-activated calcium channel inhibitors containing the above compounds as the active ingredient, wherein each substituent is defined in the specification.The present invention also relates to a pharmaceutical composition containiing an effective amount of the compound of formula (I) and a pharmaceutically effective carrier.The present invention further relates to methods of treatment of diseases associated with calcium release-activated calcium channels, diseases associated with IL-2 production, and methods of treatment of allergic, inflammatory or auto-immune diseases.
Yamanouchi Pharmaceutical Co., Ltd.
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Hirokazu Keizou Yoshinori Jun Akira Yasuhiro Makoto Souichirou Masashi
Kubota Sugasawa Okamoto Ishikawa Toyoshima Yonetoku Takeuchi Kawazoe Funatsu