Sunstein Kann Murphy & Timbers LLP
1,4-disubstituted naphthalenes as inhibitors of p38 map kinase
Naphthalene-based compounds having linked heterocyclic and aromatic rings capable of inhibiting P38, methods for inhibiting P38 in vivo or in vitro, diagnostics for determining activity in the treatment of P38 and/or cytokine-associated conditions and methods for treating conditions associated with P38 activity or cytokine activity; more particularly naphthalene-based compounds of Formula (I) having a morpholine heterocyclic ring, and methods of use thereof
ArQule, Inc.
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Syed M. Mark A. Woj Jason Yanbin
Ali Ashwell Wrona Hill Liu