Sidley Austin LLP
IL-17C related mammalian cytokine polypeptides
The present invention is directed to novel polypeptides having sequence identity with IL-17 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders.
Genentech, Inc.
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C07K A61K C12N A61P C07K C07K A61P C07K C07K
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Austin Jian Ellen William I. Audrey Hanzhong
Gurney Chen Filvaroff Wood Goddard Li