Sterne Kessler Goldstein & Fox, P.L.L.C.
Pharmaceutical compositions and methods for delivering nucleic acids into cells
The present invention relates to methods of delivering nucleic acids into cells using a nucleic acid binding molecule containing a multimeric or spacer-incorporated protein transduction domain (PTD). The invention also relates to novel compositions that contain a nucleic acid complexed or conjugated with a nucleic acid binding molecule. The nucleic acid binding molecule may contain a multimeric or spacer-incorporated PTD, and may further contain a nucleic acid binding region. The nucleic acid complexes or conjugations of the present invention may be employed to inhibit expression of a target gene, and/or determine the function of a target gene.
ForHumanTech. Co., Ltd.
C C Y C A Y A Y
C12N C07K Y10S C07K A61P Y10S A61K Y10S
inventional additional additional additional inventional additional inventional additional
Sang-Kyou Seung-Kyou Ki-Doo
Lee Lee Choi