Fish & Richardson P.C.
Transcriptional regulatory element and its use in enhancing the expression of heterologous protein
Provided is a polynucleotide, the polynucleotide can be used as a WXRE transcriptional regulatory element used to increase the protein expression level of a protein expression system. A protein expression vector or a protein expression system comprising the above-mentioned WXRE transcriptional regulatory element as well as the use thereof are also provided. The use of the WXRE transcriptional regulatory element can increase the expression level of a heterologous protein greatly with its biological activity unchanged.
WuXi Biologies Ireland Limited
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Lili Zheng Chris Chuanlong Xiaolu Jill Yarong Weichang Yuchen Huifang
Mu Zhang Chen Tang Li Cai Li Zhou Zhang Dong