McCarter & English LLP
Triazole compounds that modulate HSP90 activity
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a pharmaceutical composition comprising such a compound.
Synta Pharmaceuticals Corp.
A C C C C C A C C A C A C A C C A C A A C C A C Y A A C C C A A A A
A61P C07D C07D C07D C07D C07D A61K C07D C07D A61P C07D A61K C07D A61K C07D C07D A61K C07D A61K A61K C07D C07D A61P C07D Y02A A61P A61K C07D C07D C07D A61P A61K A61P A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional additional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Stefan M. Joseph A. Weiwen Minghu Dinesh U. Shijie Junghyun
Schweizer Burlison Ying Song Chimmanamada Zhang Chae