β-Lactams, methods for the preparation of taxanes, and sidechain-bearing taxanes
Novel β-lactams finding utility as intermediates in the preparation of sidechain-bearing taxanes such as taxol and taxol derivatives. The present invention also relates to novel methods of coupling β-lactams to form such sidechain-bearing taxanes, and to novel sidechain-bearing taxanes.
Bristol-Myers Squibb Company
C A C
C07D A61P C07D
inventional inventional inventional
John K. Ivan D. Wen-Sen David J.
Thottathil Trifunovich Li Kucera