Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
The present invention relates to novel cationic lipids, transfection agents, microparticles, nanoparticles, and short interfering nucleic acid (siNA) molecules. The invention also features compositions, and methods of use for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity in a subject or organism. Specifically, the invention relates to novel cationic lipids, microparticles, nanoparticles and transfection agents that effectively transfect or deliver biologically active molecules.
Sirna Therapeutics, Inc.
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Weimin Kurt Chandra Ye Tongqian
Wang Vagle Vargeese Zhang Chen