Wenderoth, Lind & Ponack, L.L.P.
Sulfonic acid salt compound of 4-carbamoyl-5-hydroxy-imidazole derivative
The object is to provide a stable SM-108 derivative, which is effective as a carcinostatic agent, particularly an SM-108 derivative having good storage stability. An SM-108 compound having good storage stability can be produced by producing an organic sulfonic acid salt compound of SM-108. Further, a crystalline SM-108 compound containing a trace amount of an organic carboxylic acid can be produced by using an aqueous solution of the organic sulfonic acid salt of SM-108, and by adding an alkali metal salt of an organic carboxylic acid to the aqueous solution to neutralize the aqueous solution and then causing the crystal precipitation in the solution.
Fujifilm Corporation
C A A
C07D A61P A61P
inventional inventional inventional
Yusuke Chihiro Makoto Nobuo
Higuchi Kondo Sunagawa Kato