Jones Day
Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators
This invention provides a compound of formula IAwhere X═O or S; Y is O or S; q=1 or 0; and other substituents are defined herein. Such compounds can affect the opening of, or otherwise modulate, voltage-gated potassium channels. They are potentially useful for the treatment and prevention of diseases and disorders which are affected by activation or modulation of potassium ion channels. One such condition is seizure disorders.
Valeant Pharmaceuticals International
C A A C A
C07D A61P A61P C07D A61P
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Huanming Jean-Michel Gary Lee Ian Wayne Jim Zhen Martha Alicia
Chen Vernier Larson Cheney Wu De La Rosa