Modulators of the glucocorticoid receptor and method
Novel non-steroidal compounds are provided which are glucocorticoid receptor modulators which are useful in treating diseases requiring glucocorticoid receptor agonist or antagonist therapy such as obesity, diabetes, inflammatory and immune disorders, and have the structure where Z is CONR1R2 or CH2NR1R2 and where R, Ra, Rb, Rc, Rd, Z, A and B are defined herein.
Bristol-Myers Squibb Co.
A C A C A A C A A C C C A C C A A A A A A A A A A C A C A C A C C C C C A C C C A C C A A A A A A C C A C A C C C C A C A A A A C A A A A C A A C C
A61K C07D A61P C07D A61P A61P C07D A61K A61P C07D C07D C07D A61P C07D C07D A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C07D A61P C07D A61P C07D A61P C07D C07D C07D C07D C07D A61P C07D C07D C07D A61P C07D C07D A61P A61P A61P A61P A61P A61P C07D C07D A61P C07D A61P C07D C07D C07D C07D A61P C07D A61P A61P A61K A61P C07D A61P A61P A61P A61P C07D A61P A61P C07D C07D
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Wenying Xiao-Tao Kenneth J. Wayne Tram David R. Bingwei Vera Arthur M. Lidia Soong-Hoon
Li Chen Leavitt Vaccaro Huynh Tortolani Yang Doweyko Doweyko Kim