1,2,5-substituted benzimidazoles as FLAP modulators
The present invention relates to compounds of Formula (I),and solvates, hydrates, and pharmaceutically acceptable salts thereof, wherein ring A, R1, R5 and R6 are as defined herein, useful as FLAP modulators. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.
Janssen Pharmaceutica NV
A C A C C C A A C C A A A
A61K C07D A61P C07D C07D C07D A61K A61K C07D C07D A61K A61P A61K
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Virginia M. Charlotte James P. Wenying Alec D. Curt A. Kyle T. Jing Steven D. Paul J. Wendy
Tanis Deckhut Edwards Chai Lebsack Dvorak Tarantino Liu Goldberg Krawczuk Eccles