Howson and Howson
Indoline derivatives
This invention relates to substituted indoline derivative compounds which are antagonists of the progesterone receptor, their preparation and pharmaceutical utility, particularly including contraception and treatment of benign or malignant neoplastic diseases, having the general structure: wherein R1 and R2 may be single substituents or fused to form spirocyclic rings.
American Home Products Corporation Ligand Pharmaceuticals, Inc.
A A C C A C C A C C A C A
A61P A61P C07D C07D A61P C07D C07D A61P C07D C07D A61P C07D A61P
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Lori L. Andrew Jay E. Lin Puwen John W. Todd K. James P. Christopher M. Reinhold H. W.
Miller Fensome Wrobel Zhi Zhang Ullrich Jones Edwards Tegley Bender