Klarquist Sparkman, LLP
Foldable polymers as probes
Disclosed herein are novel probes, which can be used to detect and identify target molecules of interest in a sample. The disclosed probes can be used to monitor conformational changes induced by molecular recognition events in addition to providing signaling the presence and/or identity of a target molecule. Methods, including solid phase synthesis techniques, for making probe molecules that exhibit changes in their optical properties upon target molecule binding are described in the disclosure. Also disclosed herein are novel chromophore moieties, which have tailored fluorescent emission spectra.
Washington State University Research Foundation
G Y G Y G G G G C
G01N Y10S G01N Y10T G01N G01N G01N G01N C40B
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Alexander D. Q. Wei
Li Wang