Pyrrolidine bicyclic compounds and its derivatives, compositions and methods of use
N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, salts or prodrugs thereof have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by PDF inhibitors, such as treatment of bacterial infections.
Vicuron Pharmaceuticals Inc.
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A61P C07D A61P C07D C07D C07D C07D
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Jason G. Zhengyu Jeffrey Dinesh V. Rakesh K.
Lewis Yuan Jacobs Patel Jain