Brinks Hofer Gilson & Lione
Secreted polypeptides that stimulate release of proteoglycans from cartilage
The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
Genentech, Inc.
A C
A61K C07K
additional inventional
Ellen Paul J. Audrey William I. Austin L. J. Christopher
Filvaroff Godowski Goddard Wood Gurney Grimaldi