Rse receptor activation
 An activator of the Rse receptor protein tyrosine kinase has been identified which is encoded by growth arrest-specific gene 6 (gas6). Accordingly, the present invention provides a method of activating the Rse receptor by exposing a cell comprising the Rse receptor to exogenous gas6 polypeptide. Moreover, the present invention is directed to a method for enhancing the survival, proliferation or differentiation of a cell comprising a Rse receptor by exposing the cell to exogenous gas6 polypeptide. The types of cells which can be treated according to the method include glial cells such as Schwann cells. 
Genentech, Inc.
C A
C07K A61K
inventional additional
Ronghao Paul J. Melanie R. R. Glenn Jennie P. Jian
Li Godowski Mark Hammonds Mather Chen