Factor Xla inhibitors
The present invention provides a compound of Formula I (The chemical formula should be inserted here.) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.
Merck Sharp & Dohme Corp.
C C C A C A C C
C07D C07D C07D A61P C07D A61P C07D C07D
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Sung-Sau Eric Heping Linda L. Weiguo Scott D. Zhuyan Wanying Anthony K. Amjad Rongze
So Mertz Wu Brockunier Liu Edmondson Guo Sun Ogawa Ali Kuang