Schwegman Lundberg & Woessner, P.A.
10-α/β-D-arabinofuranosyl-undecenes as potential anti-mycobacterial agents and process for the preparation thereof
Disclosed herein is 10-α/β-D-Arabinofuranosylundecenes of general Formula (II) or pharmaceutically acceptable salts thereof as anti-mycobacterial agents in vitro; (II) wherein R, R1 and R″ are as defined herein in the specification. The present invention also discloses a simple stereoselective synthesis 10-α/β-D-Arabinofuranosylundecenes of Formula (II) to target enzymes involved in the biosynthesis of cell wall of Mycobacterium and thus useful as inhibitors in the Mycobacterium tuberculosis drug development.
Council of Scientific and Industrial Research
C C A C
C07D C07D A61P C07H
inventional inventional inventional inventional
Sampa Ramana Venkata Dhiman Rahul Shivaji
Sarkar Chepuri Sarkar Patil