Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
Disclosed are compounds of formula (I): wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
Boehringer Ingelheim Phamaceuticals, Inc.
A C A A
A61P C07D A61K A61K
inventional inventional inventional inventional
Sanxing Jiang-Ping Erick Darren Ming-Hong Peter John Roman Wolfgang Pier Eugene Ronald John Charles L. Tina Can Jonathan Weimin Daniel Richard
Sun Wu Young DiSalvo Hao Nemoto Ginn Fleck Cirillo Hickey Sorcek Cywin Morwick Mao Emeigh Liu Marshall