Foley & Lardner
Peptide sequence that forms mucin sugar chain and technique for modifying protein to be linked with mucin sugar chain
 An amino acid sequence that can specifically introduce a mucin type sugar chain into a protein or peptide chain and a technique of introducing a mucin type sugar chain into protein or peptide by utilizing such a sequence are disclosed. GalNAc moiety of UDP-GalNAc (where UDP represents uridine 5'-diphosphate and GalNAc represents N-acetylgalactosamine) is introduced into the amino acid X(O) in the presence of UDP-GalNAc: polypeptide .alpha.1, O-GalNAc transferase (O-GalNAc T): EQU X(-1)-X(0)-X(1)-X(2)-X(3) (I) where X(-1) and X(2) represent independently any amino acid, X(O) represents T or S and X(1) and X(3) represent independently any amino acid except that at least one of X(1) and X(3) represents P. 
Kirin Beer Kabushiki Kaisha
C C C
C07K C12P C07K
inventional inventional inventional
Aruto Makoto
Yoshida Takeuchi