Oxadiazole transient receptor potential channel inhibitors
The invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain. 
Genentech, Inc.
A C A A C C C C A A C
A61P C07D A61K A61P C07D C07D C07D C07D A61P A61P C07D
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Claudio Huifen Jack Alexander Lea Matthew Francis Elisia Chantal Robin Luce Martin
Sturino Chen Terrett Constantineau-Forget Volgraf Beaumier Villemure Grand-Maître Larouche-Gauthier Lépissier Déry