Lewis Roca Rothgerber Christie LLP
Biphenyl-ethyl-pyrrolidine derivatives as histamine H3 receptor modulators for the treatment of cognitive disorders
The present invention relates to compounds of Formula (Ia) and pharmaceutically acceptable salts, solvates, and hydrates thereof, that modulate the activity of the histamine H3 receptor (Ia). Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of histamine H3-associated disorders.
ARENA PHARMACEUTICALS, INC.
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A61P C07D A61P A61P C07D A61P A61P A61P A61P C07D A61P A61P A61P A61P A61P C07D C07D A61P A61P
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Graeme Jonathan A. Zheng Yifeng Thuy-Anh Albert S.
Semple Covel Wei Xiong Tran Ren