McCarter & English LLP
Therapeutics targeting truncated adenomatous polyposis coli (APC) proteins
The described invention provides small molecule anti-cancer compounds that selectively target and inhibit measurable biological activity of truncated APC proteins, an immortalized Human Colonic Epithelial Cell (HCEC) model, and pharmaceutical compositions comprising at least one of the small molecule anti-cancer compounds and a pharmaceutically acceptable carrier.
Board of Regents of the University of Texas System
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Jerry W. Jef Wentian
Shay De Brabander Wang