JCIPRNET
Method for preparing troxerutin ester using whole-cell catalysis
A method for preparing troxerutin ester using whole-cell catalysis belongs to the fields of biological catalysis and pharmaceutical chemistry. The method specifically includes the following steps: evenly mixing troxerutin and a mixed organic solvent containing pyridine, then adding an acyl donor and a whole-cell catalyst, and performing a reaction under oscillation at a reaction temperature of 25° C. to 55° C.; and after the reaction is finished, separating and purifying a product by column chromatography or thin-layer chromatography, so as to obtain the troxerutin ester. The invention has the advantages of mild reaction conditions, environmental friendliness, simple process, fewer side reactions and high selectivity.
SOUTH CHINA UNIVERSITY OF TECHNOLOGY
C C
C12N C12P
inventional inventional
Xuan Xiaofeng Guanglei
Xin Li Zhao