Moore & Van Allen, PLLC
Method of producing 3-hydroxypropionic acid from glycerol
The present invention relates to a novel method of producing 3-hydroxypropionic acid from glycerol, and more particularly to a method of producing 3-hydroxypropionic acid by culturing in a glycerol-containing medium a mutant microorganism obtained by amplifying an aldehyde dehydrogenase-encoding gene in a microorganism having the abilities to produce coenzyme B12 and produce 3-hydroxypropionic acid using glycerol as a carbon source. The present invention enables the fermentation of glycerol even under microaerobic or aerobic conditions without having to add coenzyme B12. Thus, the invention will be very suitable for the development of biological processes for producing large amounts of 3-hydroxypropionic acid.
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
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C07K C12P C12P C12N C12P C12N
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Sun-Yeon Jeong-Woo Lianhua Pil-Soo Baek Rock Chul-Ho
Heo Seo Luo Seo Oh Kim