Ropes & Gray LLP
Anti-ED-A immunoconjugates for inflammatory bowel disease
Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.
Philogen S.p.A.
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A61P A61K C07K A61P A61P A61P A61K A61P A61K A61K A61K C07K A61K C07K A61P C07K
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Kathrin Denise M. Melanie C. Giovanni Jianqing
Schwager O'Hara Ruzek Neri Chen