Woodcock Washburn LLP
Amide linked modulators of γ-secretase
The present invention relates to compounds of Formula I as shown below, wherein the definitions of A, R1 R2, R3, R4, R5, R6, R7, and R8 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.
Janssen Pharmaceutica N.V.
A C A
A61P C07C A61P
inventional inventional inventional
Chih Yung
Ho