Seed IP Law Group LLP
Chemical fluorescent probes for detecting biofilms
The present invention relates to a family of fluorescent compounds based on the BODIPY scaffold, and methods for the preparation of said compounds. The present invention further relates to the use of said compounds for the detection of bacterial biofilms, wherein the bacterial biofilm comprises Pseudomonas aeruginosa and the compound specifically binds to a Fap protein of Pseudomonas aeruginosa, or wherein the compound specifically binds to bacterial cells that contain high levels of cyclic-di-guanosine-monophosphate (c-di-GMP).
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH NANYANG TECHNOLOGICAL UNIVERSITY NATIONAL UNIVERSITY OF SINGAPORE
A G G G C
A61K G01N G01N G01N C07F
inventional additional inventional inventional inventional
Liang Young-Tae Sahu Jun-Young Michael Christian
Yang Chang Srikanta Kim Givskov