Westerman, Hattori, Daniels & Adrian, LLP
Intermediates of sitagliptin and preparation process thereof
Disclosed are intermediates of Sitagliptin, a preparation process thereof, and a process for synthesizing Sitagliptin using these intermediates. Sitagliptin is synthesized by using chiral amino compounds as a raw material, without having to build a chiral center with a chiral asymmetric catalytic hydrogenation, and high-pressure hydrogenation is avoided.
ZHEJIANG HISOAR PHARMACEUTICAL CO., LTD.
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inventional inventional inventional inventional inventional inventional inventional inventional inventional
Mingwang Libo Wansheng Weijin Tianhua Xianhua Qunhui Minhuan Fei
Huang Ruan Yu Li Ma Pan Zhang He Deng