Ballard Spahr LLP
MAP4K4 (HGK) inhibitors
The invention provides mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) inhibitors, and pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant diminution of tumor cell growth, cancer or metastasis.
SRI International
A C C A C C C A C C C A C
A61P C07D C07D A61K C07D C07D C07D A61P C07D C07D C07D A61P C07D
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Jaehyeon Ling Chih-Tsung
Park Jong Chang