Knobbe, Martens, Olson & Bear LLP
Peptide nucleic acid based guanidinium compounds
Disclosed herein are transmembrane transporter compounds containing guanidinium groups to enhance transport of a polymer backbone across biomembranes. Therapeutic and other biologically active moieties may be attached to the compounds. The polymer backbone may include peptide nucleic acid monomer units.
Nitto Denko Corporation
A A A A C
A61P A61K A61P A61K C07K
inventional inventional inventional inventional inventional
Gang Lei Jian Chieko
Zhao Yu Liu Kitaura