McCarter & English, LLP
Thiazolopyrrolidine inhibitors of ROR- γ
Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORγ. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.
Vitae Pharmaceuticals, Inc.
C C
C07D C07D
inventional inventional
Lanqi Suresh B. Linghang Yajun Yi Wei Colin M. Andrew Lawrence Wayne Stephen D. Jing David A. Chengguo
Jia Singh Zhuang Zheng Fan Zhao Tice Marcus Dillard Lotesta Yuan Claremon Dong