Wood, Phillips, Katz, Clark & Mortimer
Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
A method for the inhibition of the binding of α4β1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which α4β1 is involved.
Encysive Pharmaceuticals Inc.
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A61P A61P C07D A61P C07D C07D C07D C07D C07D C07D A61P C07D A61P A61P C07D A61P C07D C07D C07D A61P C07D C07D A61P C07D A61P A61P C07D C07D C07D
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Ronald J. Jamal M. Chengde George W. Wen Robert V. Ian L. Qi Jian E. Radford
Biediger Kassir Wu Holland Li Market Scott Chen Li Decker