Pyrrolopyrazine kinase inhibitors
The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula I,wherein the variables are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.
Hoffmann-LaRoche Inc.
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Joshua Stephen M. Achyutharao Counde Shaoqing Javier de Vicente Xiaohu Ce Peter Michael Michael Kin-Chun Thomas Johannes Cornelius Ryan Craig Matthew Michael Matthew C. Fernando Hongju Allen John
Kennedy-Smith Lynch Sidduri O'yang Chen Fidalgo Zhang Wang Wovkulich Soth Luk Hermann Schoenfeld Hamilton Lucas Padilla Li Lovey