Sughrue Mion, PLLC
Crystalline form of 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and pharmaceutical composition comprising same
The present invention relates to a novel crystalline form of 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and a pharmaceutical composition containing the same. The novel crystalline form of a compound according to the present invention exhibits excellent stability even in high-temperature and humidity environments, and thus can be favorably used to prevent or treat diseases, such as thrombosis, myocardial infarction, atherosclerosis, inflammation, stroke, angina pectoris, restenosis after angioplasty, and thromboembolism.
GREEN CROSS CORPORATION LEGOCHEM BIOSCIENCES, INC.
C C A C A A C A
C07D C07D A61P C07D A61P A61K C07B A61P
inventional inventional inventional inventional inventional inventional additional inventional
Sung Ho So-Hyun Yong Zu Jae Yeon Sang Eun Suk Ho Dae Yon Sung Yoon Yoo Hoon Young Lag Jungsub Soongyu Tae Kyo Ho Young
Woo Yoon Kim Kim Chae Lee Lee Baek Kim Cho Choi Choi Park Song