Lawsonia intracellularis vaccines
The present invention relates to polynucleotide sequences encoding novel Lawsonia intracellularis polypeptides. It also relates to DNA fragments, recombinant plasmid DNA and live recombinant microorganisms comprising these sequences. Moreover, the invention relates to polypeptides encoded by these nucleotide sequences. The invention also relates to immunogenic compositions for prevention of Lawsonia intracellularis infections and methods for the preparation of these immunogenic compositions. The invention also relates to diagnostic tests for the detection of Lawsonia intracellularis DNA, the detection of Lawsonia intracellularis antigens and detection of antibodies against Lawsonia intracellularis. 
Intervet Inc.
C G A A A A A
C07K G01N A61K A61K A61P A61P A61K
inventional inventional inventional additional inventional inventional additional
Stephanie M. Yuanzheng Mohamad A. Qing
Cook Zhang Morsey Zhang