Panitch Schwarze Belisario & Nadel LLP
Crystal form of orexin receptor antagonist compound, and preparation method and application thereof
Disclosed are a preparation method of an orexin receptor antagonist compound 5-3, Crystalline forms I-IV of an orexin receptor antagonist compound 5-3 are provided. Also provided are processes of the preparing the orexin receptor antagonist compound 5-3 and its crystalline forms, as well as methods of using the crystalline forms I-IV for treating an orexin-related disease.
Yangtze River Pharmaceutical Group Co., Ltd. Shanghai Haiyan Pharmaceutical Technology Co., Ltd.
A A C A A A A
A61K A61P C07D A61K A61P A61P A61P
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Yuan Yuhe Haiying Weidong Zheng Dakun Songliang Xiaolin Zhi
Chen Wang He Li Wang Qin Wu Li Luo