Ice Miller LLP
Crystal form of dapagliflozin intermediate and preparation method therefor
Disclosed are a crystal form of a dapagliflozin intermediate and a preparation method therefor, and specifically disclosed are a crystal form of the dapagliflozin intermediate (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyOphenyl)-2-ethoxy-6-(methylhydroxyl) tetrahydro-2H-pyran-3,4,5-triol and a preparation method therefor. The advantages thereof lie in that an intermediate can be highly purified to obtain a sample with a purity of 99.3% or more, which has an important significance for improving the quality of the dapagliflozin, and the preparation process is simple and suitable for industrial production.
Jiangsu Hansoh Pharmaceutical Group Co., Ltd.
C A C C C C
C07D A61P C07B C07H C07H C07H
inventional inventional additional inventional inventional inventional
Xiang Lei Haizhou Jinjia Jun Zuyin
Li He Yu Wang Yu Du