Foley & Lardner
Indolinone compounds as kinase inhibitors
The invention relates to certain indolinone compounds, their method of synthesis, and a combinatorial library consisting of the indolinone compounds of the invention. The invention also relates to methods of modulating the function of protein kinases using indolinone compounds of the invention and methods of treating diseases by modulating the function of protein kinases and related signal transduction pathways.
Sugen, Inc.
C C C C C
C07D C07D C07D C07D C07D
inventional inventional inventional inventional inventional
G. Davis Xiaoyuan Gerald Todd Anthony Shahrzad Peng Cho Chung Chen Congxin Li
Harris, Jr. Li McMahon Miller Shirazian Tang Wei Liang Sun