The Genomics Institute of the Novartis Research Foundation
Compounds and compositions as TLR activity modulators
The invention provides a novel class of compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 7. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine.
IRM LLC
A A C A A A A A A A A A A A C A A A
A61P A61P C07D A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C07F A61P A61P A61P
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David Manmohan Yongkai Alex Kathy Tom Yao Hsiang Xiaoyue
Skibinski Singh Li Cortez Yue Wu Zhang