Extended betulinic acid analogs
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I and II:These compounds are useful for the treatment of HIV and AIDS.
ViiV HEALTHCARE UK (NO.5) LIMITED
C A
C07J A61P
inventional inventional
Sing-Yuen Yan Jacob Nicholas A. Alicia Jie
Sit Chen Swidorski Meanwell Regueiro-Ren Chen