C-3 and C-17 modified triterpenoids as HIV-1 inhibitors
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula I: These compounds are useful for the treatment of HIV and AIDS. 
ViiV HEALTHCARE UK (NO. 5) LIMITED
C C C C A
C07J C12N C07J C12N A61P
inventional additional inventional inventional inventional
Richard A. Ira B. Jie Ny Brian Lee Sing-Yuen Nicholas A. Jacob Beata Alicia Yan
Hartz Dicker Chen Sin Venables Sit Meanwell Swidorski Nowicka-Sans Regueiro-Ren Chen