Edwards Angell Palmer & Dodge LLP
Pyrimidine derivatives for treatment of hyperproliferative disorders
Pyrimidine derivatives of formula (I)in which J and Y represent aromatic or heteroaromatic rings; R2, G, G′, and G″ represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.
Bayer Pharmaceuticals Corporation
Jianqing Julie A. Chunguang Michael Donald Martin F. Ann-Marie Lin Manoj Yuanwei Lei Alexander Wenlang Ming Dhanapalan Brian R.
Chen Dixon Wang Brands Bierer Hentemann Bullion Yi Patel Chen Zhang Hillisch Fu Wang Nagarathnam Bear