Klarquist Sparkman, LLP
CTLA-4 protein variants
Protein variants of CTLA-4, which show increased activity compared to wild-type in a cell assay and which exhibit increased stability. Such variants are useful for treatment of disorders whereby attenuation of the T cell response would be beneficial.
MedImmune Limited
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A61P A61P A61P A61P A61P C07K
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Lutz Ulrich Jochen Wilhelm Ruth Mark Terence Andrew Grier
Jermutus Franks Liddament Buchanan