Connolly Bove Lodge & Hutz LLP
4-AMINO-5,6-SUBSTITUTED THIOPHENO [2,3-D] PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND THEIR USE IN THE TREATMENT OR PREVENTION OF PDE7B-MEDIATED DISEASES AND CONDITIONS
The invention relates to 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same and their use to treat or prevent diseases and conditions mediated by the phosphodiesterase enzyme 7B (PDE7B). Diseases and conditions mediated by PDE7B include osteoporosis, osteopenia and asthma.
Bayer Pharmaceuticals Corporation
A A A A A C A A A A A A C A A A A A C A C A A A A A A A A A A A C
A61P A61P A61P A61P A61K C07D A61P A61P A61P A61P A61P A61P C07D A61P A61P A61P A61K A61P C07D A61P C07D A61P A61K A61K A61P A61P A61P A61P A61P A61P A61P A61P C07D
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Barry Dongping Donald E. Andreas Yuanwei William J. Mary Katherine
Hart Fan Bierer Stolle Chen Scott Monahan