Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
Freeze-dried conjugate structure for point-of-care testing (POCT) immunochromatography, immunoassay kit comprising the same, and method for analysis using the kit
Described are immunoassay kits having a conjugate structure separate from an immunochromatographic strip in which the conjugate structure is freeze-dried with uniform droplet size, and related compositions and methods. The unique structure of the kits described here permits sample containing analyte to be reacted uniformly with the conjugate structure before being subjected to immunochromatography by application to the strip. This results in improved performance of the assay. In addition, the freeze-dried conjugate structure can be stored without contamination and is easy to carry. In addition, the freeze-dried conjugate structure can be rapidly and uniformly dissolved so that it is immediately allowed to react with a mixture of a buffer and a sample, the reaction product then being analyzed by immunochromatography, making it suitable for use in point-of-care testing.
SD Biosensor, Inc.
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inventional additional additional inventional inventional additional inventional
Sung Yub Hee Young Hyoung Gil Hyo Keun
Hong Hwang Choi Lee