Stable growth hormone compounds resistant to proteolytic degradation
The present invention relates to growth hormone (GH) compounds having additional disulphide bridges and at least one additional single point mutation making the compounds resistant to proteolytic degradation.
NOVO NORDISK HEALTHCARE AG
A C A A A A
A61P C07K A61P A61K A61P A61K
inventional inventional inventional inventional inventional additional
Jianhe Christine Brunn Leif Helle Peter
Chen Schioedt Noerskov-Lauritsen Demuth Thygesen