Sughrue Mion, PLLC
Alpha-arylmethoxyacrylate derivative, preparation method thereof, and pharmaceutical composition containing same
The present invention relates to an alpha-arylmethoxyacrylate derivative, a preparation method thereof and a pharmaceutical composition comprising the same, and the alpha-arylmethoxyacrylate derivative is inhibitory of HIF, which plays an important role in the regulation of genes associated with energy metabolism, vasomotion, angiogenesis and apoptosis and in the response of cells under hypoxic conditions, so that it can be used for preventing or treating of diseases such as cancer, arthritis, psoriasis, diabetic retinopathy and macular degeneration.
Oscotech Inc.
A A C C A A C A A A A A A C C A A C A A A C C C C C C A
A61P A61P C07C C07D A61K A61K C07D A61K A61K A61P A61K A61K A61K C07C C07C A61K A61K C07D A61P A61P A61P C07D C07C C07C C07C C07D C07D A61K
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Se-Nyum Guo Fan Sung-Ho Dae-Pil Jhi Youn Ho Se-Won Ji Min Jung Ho Dong-Sik
Kim Jin Park Kang Zheng Han Kim Kim Kim Jung