Flynn, Thiel, Boutell & Tanis, P.C.
Material for activating epidermal cell multiplication
The present invention provides a novel material for activating epidermal cell multiplication on which not only effective adhesion and multiplication of human and mammalian epidermal cells is accomplished also intercellular adhesion is promoted to form a plain cellular layer. The present invention provides a material for activating epidermal cell multiplication which contains silk fibroin of &agr;-type or &agr;-helix X-ray diffraction pattern as a principal constituent. The present material fulfills the principal requirements for activating epidermal cells of greatly improved cellular adhesion rate, multiplication, intercellular adhesion and growth of cell layers.
Japan as represented by Director General of National Institute of Sericultural and Entomological Science, Ministry of Agriculture, Forestry and Fisheries
C A C C
C12N A61L C12N C12N
additional inventional inventional inventional
Yoko Hiromi Kozo
Takasu Yamada Tsubouchi