&bgr;-lactams, methods for the preparation of taxanes, and sidechain-bearing taxanes
Novel &bgr;-lactams finding utility as intermediates in the preparation of sidechain-bearing taxanes such as taxol and taxol derivatives. The present invention also relates to novel methods of coupling &bgr;-lactams to form such sidechain-bearing taxanes, and to novel sidechain-bearing taxanes.
Bristol-Myers Squibb Company
C C A
C07D C07D A61P
inventional inventional inventional
Ivan D. David J. John K. Wen-Sen
Trifunovich Kucera Thottathil Li