Fish & Richardson P.C.
Segmenting biological structures from microscopy images
A method performed by one or more processors, includes: receiving an image to be segmented into one or more representations of one or more biological structures; accessing data representing a set of biological structures that are derived from other biological structures delineated in a training image, wherein the training image is associated with a level of modality that corresponds to a level of modality associated with the image to be segmented; computing a normalized cross correlation of the received image against one or more of the biological structures in the set of biological structures; generating, based on computing, seed data representing an estimate of a spatial organization of the one or more biological structures in the received image; and segmenting, based on a normalized cross correction of the received image to the seed data, the received image into the one or more representations of the one or more biological structures.
Carnegie Mellon University
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John A. Cheng Gustavo Kunde Wei
Ozolek Chen Rohde Wang