Birch, Stewart, Kolasch & Birch, LLP
Fused heterocyclic compounds and their use as metabotropic glutamate receptor antagonists
The present invention is directed to compounds of formula I:wherein X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, R1, R2, R3, R4, and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
Astrazeneca AB
C C A C C C C C C
C07D C07D A61P C07D C07D C07D C07D C07D C07D
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David Louise Annika Methvin Martin Karin Abdelmalik Alexander Tom Tao Don
Wensbo Edwards Kers Isaac Johansson Staaf Slassi Minidis Stefanac Xin McLeod