Edwards Angell Palmer & Dodge, LLP.
Peptide having appetite stimulating activity
The present invention provides a ligand to GPR8, in particular polypeptides capable of binding to GPR8 or its amides or esters, or salts thereof, as well as DNA, encoding for such polypeptides. The ligand to GPR8 of the present invention is useful in developing a receptor-binding assay system with the use of a GPR8 expression system, for screening candidate compounds for drugs such as preventive/therapeutic agents for obesity, appetite stimulants, and prolactin production inhibitors.
Takeda Pharmaceutical Company Limited
G A C A A A A G
G01N A61K C07K A61P A61P A01K A61P G01N
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Mioko Yukio Yoshio Yuka Takuya Michiko Chieko Taiji Mika Tsukasa Masaaki
Harada Shimomura Matsumoto Adachi Watanabe Abe Kitada Asami Goto Sugo Mori