Haynes and Boone, LLP
Method of treatment of cerebral amyloid angiopathy with P75ECD peptide and/or P75ECD-FC fusion protein
A method of treating and/or preventing neurological conditions, comprising administering to a subject in need thereof a therapeutically effective amount of a p75 extracellular domain (p75ECD) or a functional fragment, variant, analogue or derivative thereof. Also provided is a method of diagnosing and/or prognosing Alzheimer's disease (AD) in a test subject comprising comparing the concentration of p75ECD and/or p75FL and/or the ratio of p75ECD:p75FL in a biological sample of the test subject to non-demented control subject(s).
SUZHOU AUZONE BIOLOGICAL TECHNOLOGY CO., LTD
A C A A A A C C A G C C G C
A61P C07K A61K A61K A61K A61P C07K C12N A61K G01N C12N C07K G01N C07K
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Yanjiang Xinfu
Wang Zhou