Saliwanchik, Lloyd & Saliwanchik
Freeze-dried hepatitis A attenuated live vaccine and its stabilizer
The present invention relates to hepatitis A vaccine, especially to a lyophilized attenuated hepatitis A vaccine which can be stored at ambient temperature for extended periods of time, and to a method for producing the same. The present invention further relates to a stabilizer for lyophilized live vaccine and its use in improving thermostability of lyophilized live vaccine during lyophilization processing and storage period after lyophilization.
Changchun Institute of Biological Products, Ministry of Public Health
C Y A A A C A A
C12N Y02A A61K A61K A61K C12N A61P A61K
additional additional inventional inventional additional additional inventional inventional
Yong Guangpu Ying Pengfu Wei Zongming Ling Jingye Zongju Jing Lingjiu Xizhen Guangpu Shuyan Yuhong Baosheng Ben Hui Jing
Xue Li Yu Wang Wang Song Zhang Liu Wan Liu Liu Zhang Li Li Xie Liang Lin Li