Kagan Binder, PLLC
Enzymatic treatment of whey proteins for the production of antihypertensive peptides and the resulting products
Enzymatic digests of whey protein concentrates were prepared using animal, bacterial and fungal proteases, and evaluated for antihypertensive activities. The highest ACE-inhibitory activity was obtained with the purified peptide β-1g (f142–148) obtained by chemical synthesis, for which an IC50 value of 0.04 mg powder.ml−1 was found. The hydrolysates derived from BiPRO™ whey protein isolate and β-1g both gave higher antihypertensive activities (IC50 values of 0.29 to 0.90 mg powder.ml−1) than the other hydrolysates tested (IC50 values of 0.96 and 1.30 mg powder.ml−1). The recovered hydrolysate can be used to treat hypertension in mammals such as humans and domestic pets such as dogs and cats.
Davisco Foods International
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A23L A23V C12P A61K A61K A61K A23L
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Anne-Francoise Line Anand Sylvie Yves Martin E.
Allain Gourley Rao Gauthier Pouliot Davis