Bicyclic ketone compounds and methods of use thereof
The invention provides novel compounds having the general formula I: wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds. 
Genentech, Inc.
C C A C A A C A A A
C07D C07D A61P C07D A61P A61P C07D A61P A61P A61P
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Blake Gregory Guiling Snahel Huifen Craig
Daniels Hamilton Zhao Patel Chen Stivala