Hanley, Flight and Zimmerman, LLC
Devices, methods, and systems of functional optical coherence tomography
The present disclosure provides systems and methods for the determining a rate of change of one or more analyte concentrations in a target using non invasive non contact imaging techniques such as OCT. Generally, OCT data is acquired and optical information is extracted from OCT scans to quantitatively determine both a flow rate of fluid in the target and a concentration of one or more analytes. Both calculations can provide a means to determine a change in rate of an analyte over time. Example methods and systems of the disclosure may be used in assessing metabolism of a tissue, where oxygen is the analyte detected, or other functional states, and be generally used for the diagnosis, monitoring and treatment of disease.
Northwestern University Opticent INC
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Ji Hao F. Vadim Wenzhong Kieren J.
Yi Zhang Backman Liu Patel