Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
Compositions and methods for treatment of cancer
The present invention relates to pyrroloquinolinyl-pyrrolidine-2,5-dione compounds in combination with chemotherapeutic agents. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention and also administering a effective amount of a chemotherapeutic agent.
ArQule, Inc.
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A61P A61K C07D C07F A61K A61K C07D A61K C07K A61K A61K C07D A61K A61K A61K C07F A61K A61P A61K A61P A61K A61K A61K A61K
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Neru Chiang J. Mark A. Magdi M. Jason
Munshi Li Ashwell Moussa Hill