Casimir Jones SC
Indole inhibitors of MDM2 and the uses thereof
The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).
The Regents of the University of Michigan
A C C
A61P C07D C07D
inventional inventional inventional
Dongguang Jiangyong Shanghai Shaomeng
Qin Chen Yu Wang