Morris, Manning & Martin, LLP
Vaccines with higher carbohydrate antigen density and novel saponin adjuvant
The present invention provides vaccines comprising carbohydrate antigen conjugated to a diphtheria toxin (DT) as a carrier protein, wherein the ratio of the number of carbohydrate antigen molecule to the carrier protein molecule is higher than 5:1. Also disclosed herein is a novel saponin adjuvant and methods to inhibit cancer cells, by administering an effective amount of the vaccine disclose herein.
OBI Pharma., Inc.
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Yu-Chen Chung Hao Cheng Der Tony Nan-Hsuan I-Ju Cheng-Chi Yih-Huang Yu-Hsin Wei Han
Lin Chang Yu Wang Chen Wang Hsieh Lin Lee