Nixon Peabody LLP
Solid state forms of racemic ilaprazole
The invention relates to crystalline forms of racemic ilaprazole, 2[[(4-methoxy-3-methyl-2-pyridinyl)-methyl]sulfinyl]-5-(1H-pyrrol-1-yl) 1H-Benzimidazole. The invention also relates to a pharmaceutical composition for inhibiting gastric acid secretion comprising a crystalline Form of ilaprazole according to the invention in an amount effective to inhibit gastric acid secretion and a pharmaceutically acceptable carrier. The invention also provides methods of treatment for various acid-related gastrointestinal (GI) disorders.
Il Yang Pharmaceutical Company, Ltd.
A C A A
A61P C07D A61P A61P
inventional inventional inventional inventional
Jih Hua Wei David T. Jinyu Stephan D. John M.
Liu Lai Jonaitis Shen Parent Brackett