Isoxazole-and isothiazole-amine compounds for the treatment of neurodegenerative disorders
The present invention relates to compounds of the Formula Iwherein R1, R3, R5, R6, R7, X and Y are as defined. Compounds of the Formula I have activity inhibiting production of Aβ-peptide. The invention also relates to pharmaceutical compositions and methods of treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
Pfizer Inc
A A A A A C A A A A
A61P A61P A61P A61P A61P C07D A61P A61P A61P A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Lei Yuhpyng L
Zhang Chen