Sim & McBurney
Nucleic acid respiratory syncytial virus vaccines
 Non-replicating vectors containing a nucleotide sequence coding for an F protein of respiratory syncytial virus (RSV) and a promoter for such sequence, preferably a cytomegalovirus promoter, are described for in vivo immunization. Such non-replicating vectors, including plasmids, also may contain a further nucleotide sequence located adjacent to the RSV F protein encoding sequence to enhance the immunoprotective ability of the RSV F protein when expressed in vivo. Such non-replicating vectors may be used to immunize a host against disease caused by infection with RSV, including a human host, by administration thereto, and may be formulated as immunogenic compositions with pharmaceutically-acceptable carriers for such purpose. Such vectors also may be used to produce antibodies for detection of RSV infection in a sample. 
Pasteur Merieux Connaught Canada
A C C
A61K C07K C12N
additional inventional additional
Suryaprakash Mary E. Michel H. Xiaomao
Sambhara Ewasyshyn Klein Li