Sterne, Kessler, Goldstein & Fox P.L.L.C.
Thiazole compounds and uses thereof
The present invention relates to a compound of Formula (I), or an isomer, pharmaceutically acceptable salt and solvate thereof; the present invention further relates to a pharmaceutical composition, which comprises the compound of Formula (I), or isomer, pharmaceutically acceptable salt or solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents; the present invention further relates to the use of the compound of Formula (I), or isomer, pharmaceutically acceptable salt or solvate thereof, for anti-apoptosis, prophylaxis or treatment of a disease or symptom associated with apoptosis, especially for protecting myocardial cells, and prophylaxis or treatment of a disease or symptom associated with cardiomyocyte apoptosis.
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
A C
A61P C07D
inventional inventional
Song Juan Wu Junhai Kunlun Xinbo
Li Liu Zhong Xiao He Zhou