Sheppard Mullin Richter & Hampton LLP
3,3-difluoroallylamines or salts thereof and pharmaceutical compositions comprising the same
The present technology provides 3,3-difluoroallylamines or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and uses thereof. The 3,3-difluoroallylamines or their pharmaceutically acceptable salts exhibit potent inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).
YUHAN CORPORATION
C A C C C C C C C C C C C C C C
C07D A61P C07D C07D C07D C07D C07D C07D C07D C07D C07D C07D C07D C07D C07D C07D
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Cheol Hee Hyok Jun Eui Chul Hee Jae Na Ry Sol Tae Dong So Young Da Na Eun Kyung Na Yeon Hyun Ho
Lim Cho Lee Tak Ha Park Han Kim Jeong Kim Yang Choi