Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
Thiazole derivative
 A thiazole compound of the formula: ##STR1## wherein T is lower alkylene; u is 0 or 1; R.sup.1 and R.sup.2 are the same or different and are each H, or lower alkyl, etc.; R.sup.3 is ##STR2## R.sup.4 is H or lower alkanoyloxy-lower alkyl, which shows inhibitory activity on protein kinase C (PKC, Ca.sup.2+ /phospholipid-depending serine/threonine protein phosphatase), and are useful as a protein kinase C inhibitor. 
Otsuka Pharmaceutical Company, Limited
C C C C C C C
C07D C07D C07D C07D C07D C07D C07D
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Takahito Kenji Isao Yoshihisa Fujio Tomoichi Kazuyoshi Toyoki Kaoru Michiaki
Yamauchi Nakaya Takemura Tanada Tabusa Shinohara Nagami Mori Abe Tominaga