Panitch Schwarze Belisario & Nadel LLP
Crystal form of orexin receptor antagonist compound, and preparation method and application thereof
Disclosed are a preparation method of an orexin receptor antagonist compound 5-3. Crystalline forms I-IV of an orexin receptor antagonist compound 5-3 are provided. Also provided are processes of preparing crystalline forms of the orexin receptor antagonist compound 5-3, as well as methods of using the crystalline forms I-IV for treating an orexin-related disease.
YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD. SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD.
A A A A A A C
A61P A61P A61K A61P A61K A61P C07D
inventional inventional inventional inventional inventional inventional inventional
Yuan Xiaolin Yuhe Zheng Zhi Weidong Haiying Songliang Dakun
Chen Li Wang Wang Luo Li He Wu Qin