Licata & Tyrrell P.C.
Antibodies, kit and method for detecting amyloid beta oligomers
This invention is a selective Aβ oligomer kit and immunoassay method capable of reliably and sensitively detecting Aβ oligomers in a biological sample of a patient. In one embodiment the inventive assay uses a pair of anti-Aβ oligomer antibodies, as capture and detection antibodies, to detect and quantify Aβ oligomers. The method can be used to differentiate Alzheimer's disease (AD) patients from non-AD patients and/or to stratify AD patients according to the severity of their disease.
Acumen Pharmaceuticals, Inc. Merck Sharp & Dohme Corp.
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Wei-Qin Fubao Alexander Paul J. Min William F. Mary J. Weirong Renee C. Ningyan Abigail L.
Zhao Wang McCampbell Shughrue Xu Goure Savage Wang Gaspar Zhang Wolfe