Antibacterial phosphoinositides
 It has been discovered that certain phosphoinositides demonstrate antibacterial activity. Particularly, these phosphoinositides have been discovered to prevent the adhesion of H. influenzae onto the nasopharyngeal cells of mammals, and, in particular, humans. Phosphoinositides useful with the present invention have the following formula: ##STR1## wherein R.sub.1 and R.sub.2 are selected from the group consisting of hydrogen and monounsaturated and saturated fatty acids having a carbon chain length of C.sub.6 to C.sub.20 and R.sub.1 and R.sub.2 can be the same or different; and R.sub.3 to R.sub.7 are selected from the group consisting of hydrogen or a phosphate moiety with at least two of R.sub.3 to R.sub.7 being a phosphate moiety; and hydrates and pharmaceutically acceptable salts thereof. 
Abbott Laboratories
A
A23L
inventional
Jonathan A. Yung-Sheng Jim-Wen Steven Neal Shie-Ming Pradip
Meulbroek Huang Liu Anderson Hwang Mukerji