Integrated ultrasound, OCT, PA and/or florescence imaging endoscope for diagnosing cancers in gastrointestinal, respiratory, and urogenital tracts
A multimodality imaging system including ultrasound, optical coherence tomography (OCT), photoacoustic (PA) imaging, florescence imaging and endoscopic catheter for imaging inside the gastrointestinal tract with real-time automatic image co-registration capability, including: an ultrasound subsystem for imaging; an optical coherence tomography (OCT) subsystem for imaging, a PA microscopy or tomography subsystem for imaging and a florescence imaging subsystem for imaging. An invasive interventional imaging device is included with an instrumentality to take a tissue biopsy from a location visible on the ultrasound subsystem for imaging, on the optical coherence tomography (OCT) subsystem for imaging, photoacoustic (PA) subsystem for imaging and florescence subsystem for imaging. The instrumentality takes a tissue biopsy from a visible location simultaneously with the visualization of the tissue about to be biopsied so that the tissue biopsy location is visualized before, during and after the biopsy.
University of Southern California The Regents of the University of California
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Jiawen Teng K. Kirk Qifa Thomas Zhongping Jacques Xiang
Li Ma Shung Zhou Cummins Chen Van Dam Li