Mendelsohn Dunleavy P.C.
Piezoelectric biochips having fluidic channels
One embodiment is a biochip having an array of biosensors for quantitative determination of protein-protein and/or antibody-antigen interactions. The array comprises at least two biosensors formed on a substrate. The biosensors can be used to detect either the same or different analytes. The biosensors may be acoustical transducers operated in the thickness shear mode of vibration, wherein the density, viscosity, and elasticity at the sensor interface can be ascertained. Additionally, a series of fluidic channels are etched to the same depth as the biosensors. The fluidic channels serve to efficiently deliver the sample to the biosensors. One or more biochips can be housed within an enclosure.
Drexel University
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B01L B01L B01L B01L B01L G01N G01N G01N
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Qiliang Johann Ertan Ryszard
Zhang deSa Ergezen Lec