Brinks Gilson & Lione
Difluorolactam compositions for EP4-mediated osteo related diseases and conditions
Disclosed herein are compositions and methods of treating osteroporosis, bone fracture, bone loss, and increasing bone density by administration of compounds of formula (I)or compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier, wherein L1, L2, L4, R1, R4, R5, R6, and s are as defined in the specification.
Cayman Chemical Company, Inc. Myometrics, LLC
A A A A A A A A A A A A A A A A A A A A A A A A A C C C
A61P A61P A61P A61P A61P A61L A61L A61L A61L A61K A61P A61L A61P A61P A61P A61P A61L A61P A61L A61L A61K A61P A61L A61L A61L C07D C07D C07D
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Stephen Douglas Andriy James Bernard Joseph Michael James Paul Gregory William Fred Lawrence Thomas Allen Bradlee David Adam
Barrett Kornilov Kramer Colombo O'Malley Endres Ciske Owen Germain Uzieblo