Sterne, Kessler, Goldstein & Fox P.L.L.C.
Anti-IL-6 monoclonal antibodies
The present invention provides novel monoclonal antibodies that bind specifically to IL-6. The antibodies of the invention comprise a variable heavy chain (VH) region selected from any of the VH regions disclosed herein as well as amino acid variants thereof, and/or a variable light chain (VL) region selected from any of the VL regions disclosed herein as well as amino acid variants thereof. The invention also provides methods of treating diseases and disorders associated with IL-6 expression and/or activity.
Vaccinex, Inc.
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A61P C07K A61P A61P A61P C07K C07K C07K A61P A61P
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Wei Ernest S.
Wang Smith