Fish & Richardson P.C.
Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors
Compounds of Formula I: and salts thereof in which R1, R2, R3, R4, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases. 
Array BioPharm Inc.
C C A A C A C A C A A A A A A A Y
C07D C07D A61K A61P C07D A61P C07D A61P C07D A61P A61P A61P A61P A61P A61P A61K Y02A
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional additional
Julia Lily Shelley Steven W. Timothy Yutong Jeongbeob Kevin Ronald
Haas Huang Allen Andrews Kercher Jiang Seo Condroski