Compounds for the treatment of neurodegenerative disorders
The present invention relates to compounds of the Formulawherein R3, R5, R7, U, X, Y and Z are as defined. Compounds of the Formula I have activity inhibiting production of Aβ-peptide. This invention also relates to pharmaceutical compositions and methods of treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
Pfizer Inc.
A A A A A C
A61P A61P A61P A61P A61P C07D
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Yuhpyng L.
Chen