The Genomics Institute of the Novartis Research Foundation
Compounds and compositions as C-kit kinase inhibitors
The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases.
NOVARTIS AG
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Bao Jon Vince Xiaolin Juliet Hank Michael James Valentina Xiaodong
Nguyen Loren Yeh Li Nabakka Petrassi Molteni Liu