Casimir Jones SC
Small molecule inhibitors of MDM2 and the uses thereof
The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).
The Regents of the University of Michigan
C A A C A C C
C12N A61P A61P C12N A61P C07D C07D
additional inventional inventional inventional inventional inventional inventional
Shanghai Jianyong Dongguang Shaomeng
Yu Chen Qin Wang