Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
Epithelial adhesive lactobacilli
 The invention refers to the use of Lactobacillus plantarum 299v having a mannose-specific adhesin for the preparation of a pharmaceutical composition inhibiting the binding of pathogenic bacteria expressing mannose-specific adhesins to the epithelial cell surface. The strain of Lactobacillus plantiarum which can be used in the invention adheres to D-mannose-coated agarose beads. The invention also refers to the use of said strain for the preparation of a pharmaceutical composition to be used in prophylatic and/or curative treatment of bacterial translocation, gastroenteritis and other diseases caused by pathogenic bacteria expressing mannose-specific adhesins. 
Probi AB
A A A Y A A Y
A61P A61P A61P Y02A A61K A61P Y02A
inventional inventional inventional additional inventional inventional additional
Goran Agnes Ingegerd Siv Marie-Louise Bengt
Molin Wold Adlerberth Ahrne Johansson Jeppsson