Mintz, Levin, Cohn, Ferris, Glovsky & Popeo, P.C.
Substituted heterocyclic inhibitors of PTPN11
The present invention relates to compounds which may be useful as inhibitors of PTPN11 for the treatment or prevention of cancer and other PTP-mediated diseases. Disclosed herein are new compounds and compounds based on pyrazolopyrazines and their application as pharmaceuticals for the treatment of disease.
NAVIRE PHARMA, INC.
C A C C A
C07D A61K C07D C07D A61P
inventional inventional inventional additional inventional
Jason Jason Philip Zhijun Timothy
Cross Burke Jones Kang Mcafoos