Morrison & Foerster LLP
Imidazopyrazine Syk inhibitors
Certain imidazopyrazines of Formula (I) and pharmaceutical compositions thereof are provided herein.Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of Syk activity, which comprises administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are provided. Also provided are methods for determining the presence or absence of Syk kinase in a sample.
Gilead Connecticut, Inc.
A A A C C A A A A C A A A G C A A A G A A A C A C
A61P A61K A61P C07D C07D A61P A61P A61P A61P C07D A61P A61P A61P G01N C12Q A61P A61P A61P G01N A61P A61P A61P C07D A61P C07D
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James P. Jianjun Antonio J. M. Peter A. Zhongdong Seung H. Scott A. David M. Soumya Kevin S. Jeffrey E. Douglas G.
Harding Xu Barbosa, Jr. Blomgren Zhao Lee Mitchell Armistead Mitra Currie Kropf Stafford