Liu Chen & Hoffman LLP
Method for dynamically removing recombinant human nerve growth factor precursor by hydrophobic interaction chromatography
A method for removing precursors in recombinant human nerve growth factor (rhNGF) by hydrophobic interaction chromatography (HIC) is provided, where a Chinese hamster ovary (CHO) cell culture is processed by column chromatography for preliminary purification, and the pretreated sample obtained therefrom is further processed in a HIC column by washing the sample and then eluting the HIC column.
XINTRUM PHARMACEUTICALS, LTD.
C C C
C12N C07K C07K
inventional additional inventional
Wenchao Hongliang Yuesheng Yi
Liu Sun Wang Zhang