Wpat, P.C., Intellectual Property Attorneys
Peptide compounds for inhibition of platelet aggregation
The invention relates to a peptide compound and its pharmaceutical composition for inhibiting platelet aggregation and preventing/treating thrombogenic diseases. The invention develops pentapeptides and hexapeptides derived from snake venom C-type lectin-like proteins (CLPs) fragments, which can inhibit platelet aggregation and have antithrombotic activity without hemorrhagic tendency. Accordingly, they can be used as potential agents for the prevention and therapy of thrombogenic diseases.
NATIONAL TAIWAN UNIVERSITY
A A A A C C A A C C A C
A61K A61K A61L A61K C07K C07K A61P A61L C07K C07K A61K C07K
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Tur-Fu Chien-Hsin Ching-Hu
Huang Chang Chung