Fish & Richardson P.C.
Substituted pyrazolo [1,5-A] pyrimidine compounds as TRK kinase inhibitors
Compounds of Formula I:and salts thereof in which R1, R2, R3, R4, X, Y and n have the meanings given in the specification, are inhibitors of Trk kinases and are useful in the treatment of diseases which can be treated with a Trk kinase inhibitor such as pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
Array BioPharma, Inc.
C A A A A A C A C A A C A A A Y C
C07D A61K A61P A61K A61P A61P C07D A61P C07D A61P A61P C07D A61P A61P A61P Y02A C07D
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional additional inventional
Kevin Ronald Steven Wade Jeongbeob Julia Lily Timothy Yutong Shelley
Condroski Andrews Seo Haas Huang Krecher Jiang Allen