Marshall, Gerstein & Borun LLP
5,6-dihydro-11H-indolo[2,3-B]quinolin-11-ones as alk inhibitors
The present disclosure provides compounds represented by Formula (I), and the pharmaceutically acceptable salts and solvates thereof wherein R1a, R1b, R2a, R2b, R3, R4, R5, R6, R7, E and (B) are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat a condition or disorder responsive to inhibition of ALK such as cancer. and ® 
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
A C
A61P C07D
inventional inventional
Chao-Yie Xuyuan Donna Shaomeng Jianyong Liu
Yang Dong McEachern Wang Chen Liu