Nixon Peabody LLP
Crystalline forms of solvated ilaprazole
The invention relates to crystalline forms of various solvates of ilaprazole, 2[[(4-methoxy-3-methyl-2-pyridinyl)-methyl]sulfinyl]-5-(1H-pyrrol-1-yl)1H-Benzimidazole. The invention also relates to a pharmaceutical composition for inhibiting gastric acid secretion comprising crystalline ilaprazole hydrate according to the invention in an amount effective to inhibit gastric acid secretion and a pharmaceutically acceptable carrier. The invention also provides methods of treatment for various acid-related gastrointestinal (GI) disorders.
Il Yang Pharmaceutical Company, Ltd.
A A C A
A61P A61P C07D A61P
inventional inventional inventional inventional
David T. Wei Jih Hua John M. Stephan D.
Jonaitis Lai Liu Brackett Parent