Method for increasing protein thermal stability
The invention provides a simple and effective method for increasing thermal stability of a wide range of proteins, comprising fusing a self-assembling amphipathic peptide to the C- or N-terminal of target proteins. The fusion protein can have a half life up to 26 times longer than that of the wild type protein.
Jiangnan University
C C C C
C12N C12N C12N C12N
inventional additional inventional inventional
Guocheng Xinyao Jian Juan Song
Du Lu Chen Zhang Liu