Flynn, Thiel, Boutell & Tanis, P.C.
Sericin-containing material, process for producing the same method of using the same
The object of the present invention is to elucidate a biologically active function of a component constituting undegraded sericin and to provide a novel medical material, cosmetic material, etc. utilizing the functional composition. Disclosed is a cell growth promoter obtainable by elution from a fiber discharged by a domestic silkworm, e.g., cocoon filaments or the like, wherein the cell growth promoter comprises sericin having a molecular weight of about 400,000 as measured by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) as a main component. This cell growth promoting agent (substance) is extremely useful because growth of cells is promoted when it is used in a wound dressing material, a vascular endothelium forming material and an organ forming material for medical use, in a cell culture base material for biological use, or in a cosmetic material for skin care use.
National Institute of Agrobiological Sciences
A C A A A A
A61Q C07K A61L A61K A61L A61P
inventional inventional inventional inventional inventional inventional
Yoko Hiromi Kozo
Takasu Yamada Tsubouchi