Foley Hoag LLP
Isoform selective HDAC inhibitors
One aspect of the invention relates to isoform-selective HDAC inhibitors. Also provided are methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy. The invention also provides methods for treating cancer, methods for treating neurological diseases and methods for treating malaria. Additionally, the invention provides pharmaceutical compositions comprising an HDAC inhibitor of the invention; and kits comprising an HDAC inhibitor of the invention.
The Board of Trustees of the University of Illinois Georgetown University
A C Y C C
A61P C07D Y02A C07C C07C
inventional inventional additional inventional inventional
Werner Yufeng Mira Anatoly Pavel A. Arsen Alan P. Hongbin
Tueckmantel Chen Jung Dritschilo Petukhov Gaysin Kozikowski Yuan