Sterne, Kessler, Goldstein & Fox P.L.L.C.
Jagged-binding agents and uses thereof
Antibodies that specifically bind to an extracellular domain of human Jagged 1 or human Jagged2 and modulate Jagged activity, and methods of using said antibodies to inhibit tumor growth are disclosed. Also described are methods of treating cancer comprising administering a therapeutically effect amount of an anti-Jagged antibody to a patient having a tumor or cancer.
OncoMed Pharmaceuticals, Inc.
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Zhimin Timothy Charles Alexandra Austin L. Aaron Ken
Ji Hoey Lazetic Gurney Sato