Jenkins, Wilson, Taylor & Hunt, P.A.
Neuropeptide Y fragment capable of releasing hematopoietic stem cells into blood and treating osteoporosis
The present invention relates to a novel peptide exhibiting an effect of releasing myelopoiesis stem cells into blood and an osteoporosis therapeutic effect and use thereof and, in particularly, to a novel peptide consisting of an amino acid sequence of SEQ. ID.NO:1 which has effects of releasing hematopoietic stem cells into a bloodstream and decreasing osteoclast cells in bone narrow, and a pharmaceutical composition comprising the novel peptide as an active ingredient for preventing or treating neutropenia, anemia or osteoporosis. Because of side effects, the peptide of the present invention not only increases level of leukocytes, red blood cells and platelets in blood, but also alleviates a decrease in bone density, and therefore, can be very usefully used for the development of a prophylactic or therapeutic agent for neutropenia, anemia or osteoporosis.
Kyungpook National University Industry-Academic Cooperation Foundation
A C A A C A
A61P C07K A61K A61K C07K A23L
inventional inventional additional inventional inventional inventional
Min Hee Hee Kyung Jae Sung
Park Jin Bae