Foley & Lardner LLP
Inhibitors of metallo-β-lactamase-enzymes
The present application relates to combination treatments for bacterial infections. For example, the application relates to the use of one or more β-lactam antibiotics and one or more compounds of Formula I: (I) for treatment of a metallo-B-lactamase-expressing bacterial infection or a disease, disorder or condition arising from a metallo-B-lactamase-expressing bacterial infection.
McMaster University
A A A Y A A A
A61K A61P A61K Y02A A61P A61K A61K
inventional inventional inventional additional inventional inventional inventional
Wenliang Andrew Gerry
Wang King Wright