Synnestvedt & Lechner LLP
Aliphatic propargylamines as cellular rescue agents
 The present invention relates to the use of a group of propargylamines of the general formula (I) ##STR1## wherein R.sup.1 is hydrogen or CH.sub.3 and R.sup.2 is (CH.sub.2).sub.n CH.sub.3 and n is an integer from 0 to 16, and salts thereof, as cellular rescue agents in the treatment and prevention of diseases in which cell death occurs by apoptosis. Some of the compounds of formula I are novel. The invention is also directed to the use of these compounds in the treatment of these diseases, as well as to processes for the preparation of the compounds. 
University of Saskatchewan
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Xinmin David Lillian Peter Alan Bruce Alick
Li Durden Dyck Yu Boulton Davis Paterson