McDonald Hopkins LLC
Conotoxin peptide κ-CPTx-BTL01, preparation method therefor, and uses thereof
Provided is a new conotoxin peptide κ-CPTx-bt101. The conotoxin peptide κ-CPTx-bt101 has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1, or has derivative polypeptide that has an amino acid sequence indicated by SEQ ID NO:1 and that is formed after substitution, addition or deletion of one or more amino acids are performed and has original functions. Also provided is polynucleotide for coding the peptide, comprising a constructed body of the polynucleotide, an expression carrier and transformed cells. A peptide preparation method and uses in the treatment of diseases related to a calcium ion channel.
BGI SHENZHEN
A C C A C C C C A
A61P C12N C12N A61K C07K C07K C07K C07K A61K
inventional inventional inventional inventional inventional inventional additional inventional inventional
Qiong Bo Ting Fen Zhilong Jie Chao
Shi Wen Tong Mo Lin Liu Peng