2,3-dihydroimidazol[1,2-C]pyrimidin-5(1-H)-one based ipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitors
The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.
GlaxoSmithKline Intellectual Property Development Limited
A A A C
A61P A61P A61P C07D
inventional inventional inventional inventional
Yingxia Qing Zehong
Sang Zhang Wan