Method of inhibiting C-KIT kinase
A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a compound of the present invention:or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof.The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.
Janssen Pharmaceutica NV
A C C C A A C A C A C A C A A A
A61K C12N C07D C07D A61K A61P C07D A61K C07D A61N C07D A61K C07D A61K A61N A61K
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M. Jonathan Renee Louise Kenneth J. Jinsheng Shelley K. Carl R. Carl M. Mark J. Christopher J. Sanath K.
Rudolph Desjarlais Wilson Chen Ballentine Illig Manthey Wall Molloy Meegalla