Non-peptidic NPY Y2 receptor inhibitors
The invention provides novel non-peptidic NPY Y2 receptor inhibitors useful in treating or preventing: anxiolytic disorders or depression; injured mammalian nerve tissue; conditions responsive to treatment through administration of a neurotrophic factor; neurological disorders; bone loss; substance related disorders; obesity; or an obesity-related disorder. Compounds of the invention are also useful in modulating endocrine functions, particularly endocrine functions controlled by the pituitary and hypothalamic glands, and are therefore useful in the treatment or prevention of inovulation and infertility.
Johnson & Johnson Pharmaceutical Research & Development, LLC
C A C A C A A A
C07D A61P C07D A61P C07D A61P A61P A61P
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Jill A. Scott L. Mark A. Wenying Mark Nicholas I. Timothy W. Dale A. Xiaobing William V.
Jablonowski Dax Youngman Chai Seierstad Carruthers Lovenberg Rudolph Li Murray