Seed IP Law Group LLP
Purified therapeutic nanoparticles and preparation methods thereof
Purified therapeutic nanoparticles are provided herein. Such nanoparticles comprise an active pharmaceutical ingredient and human serum albumin, wherein the weight ratio of human serum albumin to the active ingredient in the therapeutic nanoparticles is from 0.01:1 to 1:1, and wherein the nanoparticles are substantially free of free human serum albumin that is not incorporated in the nanoparticles. The present disclosure also provides pharmaceutical compositions that comprise the purified therapeutic nanoparticles and are also substantially free of free human serum albumin. Methods for preparing and using the purified therapeutic nanoparticles and compositions thereof are also provided.
CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD.
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A61K B82Y A61P A61K
inventional inventional inventional inventional
Yongfeng Yajuan Caixia Chunlei Min Dongjian Shixia Yanhui
Li Wang Wang Li Liang Chen Wang Li