Townsend and Townsend and Crew LLP
Isoquinolone inhibitors of factor Xa
Novel compounds of formula I: including its pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa is described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating conditions in mammals characterized by undesired thrombosis.
Millennium Pharmaceuticals, Inc.
A C C
A61P C07D C07D
inventional inventional inventional
Ting Charles K. Robert M. Wenhao
Su Marlowe Scarborough Li