Antibodies to human carboxypeptidase B and methods of use thereof
 A novel polypeptide, designated plasma carboxypeptidase B (PCPB), has been purified from human plasma. It has been cloned from a human liver cDNA library using PCR amplification. Provided herein is nucleic acid encoding PCPB useful in diagnostics and in the recombinant preparation of PCPB. PCPB is used in the preparation and purification of antibodies thereto, in the purification of plasminogen, in the inhibition of plasminogen activation by t-PA in the presence of fibrinogen, and in diagnostic assays. 
Genentech, Inc.
G A C Y
G01N A61K C12N Y10S
inventional additional inventional additional
Dan L. Dennis T.
Eaton Drayna