Oxazole compounds for the treatment of neurodegenerative disorders
The present invention relates to compounds of the Formulawherein R3, R5, R6, R7, and Z, and other variables enumerated under one or more of R3, R5, R6, R7, and Z, are as defined. Compounds of the Formula I have activity inhibiting production of Aβ-peptide. This invention also relates to pharmaceutical compositions and methods of treating diseases, for example, neurodegenerative diseases, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula I.
Pfizer Inc.
A C A C A A A C A A
A61P C07D A61P C07D A61P A61P A61P C07D A61P A61P
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Yuhpyng L.
Chen