Acylated spiropiperidine derivatives as melanocortin-4 receptor agonists
Certain novel N-acylated spiropiperidine derivatives are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.
Merck & Co., Inc.
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Zhixiong Jonathan R. Feroze Iyassu K. Ravi P. Jian Yingjie Shuwen Liangqin Tianying
Ye Young Ujjainwalla Sebhat Nargund Liu Lai He Guo Jian