Fenwick & West LLP
Isolated protein comprising an activin type IIB5 receptor polypeptide and uses thereof
The present invention provides novel activin IIB5 receptor polypeptides capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the receptor polypeptides. Compositions and methods for treating muscle-wasting, metabolic and other disorders are also provided.
Amgen Inc.
A A A A A A A A A A A A A A A A A A A A A A C A A A C
A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C07K A61P A61P A61P C07K
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Xiaolan HQ Keith Soo-Nyung
Zhou Han Kwak