7-oxo-pyridopyrimidines (I)
The present invention provides compounds of the formula: wherein R2 is substituted cycloalkyl, heterosubstituted cycloalkyl, heteroalkylsubstituted cycloalkyl, heterosubstituted cycloalkyl-alkyl, optionally substituted heterocyclyl, spiro-substituted cycloalkyl, aralkoxy, alkoxy, -alkylene-S(O)n-alkyl (wherein n is 1 or 2), or &#8212;SO2Ar2; and R1, R3, and Ar1 are those defined herein, and methods for preparation and uses thereof.
Syntex (U.S.A.) LLC
A A C C A
A61P A61P C07D C07D A61P
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James Patrick Julie Anne Jian Jeffrey David Michael
Dunn Lim Chen Goldstein