Beta-tetrazolyl-propionic acids as metallo-beta-lactamase inhibitors
The present invention relates to compounds of formula I that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.
Merck Sharp & Dohme Corp.
A C C C C C A A A C C C C C C C A C A A C A A C
A61K C07D C07D C07D C07D C07D A61K A61K A61K C07D C07D C07D C07D C07D C07D C07D A61K C07D A61K A61K C07D A61K A61K C07D
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Jing Dexi Mihir William Reynalda Shu-Wei Guoqing Li Alexander Haiqun Shuzhi Yuhua Fa-Xiang Haifeng Weidong Jianping
Su Yang Mandal Hagmann DeJesus Yang Li Xiao Pasternak Tang Dong Huang Ding Tang Pan Pan