Morgan, Lewis & Bockius LLP
Piperazine heteroaryl derivative, preparation method therefor and use of same in medicine
The present invention relates to a piperazine heteroaryl derivative, a preparation method therefor and the use of same in medicine. In particular, the present invention relates to the piperazine heteroaryl derivative as shown in the general formula (I), a preparation method therefor, a pharmaceutical composition comprising the derivative, and the use of same as a capsid protein inhibitor, in particular in the prevention and/or treatment of diseases such as hepatitis B, influenza, herpes, AIDS, etc. The definitions of each group in the general formula (I) are the same as those defined in the description.
JIANGSU HENGRUI MEDICINE CO., LTD. SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD.
C A A A A C C A A A
C07D A61P A61P A61P A61P C07D C07D A61P A61P A61K
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Weikang Xin Feng Wei Yang
Tao Li He He Chen