Nelson Mullins Riley & Scarborough LLP
Chemical linkers with single amino acids and conjugates thereof
The present disclosure provides drug-ligand conjugates that are potent cytotoxins and include a linker between the drug and ligand where the linker has a single amino acid. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.
Medarex, LLC
A C A A C C A A A C A
A61P C07D A61P A61P C07K C07D A61P A61K A61P C07D A61K
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Nils Liang Vincent Sanjeev Qian
Lonberg Chen Guerlavais Gangwar Zhang