Edwards Angell Palmer & Dodge LLP
Ligand to GPR8
The present invention provides a ligand to GPR8, in particular polypeptides capable of binding to GPR8 or its amides or esters, or salts thereof, as well as the DNA encoding for such polypeptides. The ligand to GPR8 of the present invention is useful in developing receptor-binding assay systems with the use of a GPR8 expression system, for screening candidate compounds for drugs such as preventive/therapeutic agents for obesity, appetite stimulants, and prolactin production inhibitors.
Takeda Pharmaceutical Company Limited
A A G C A A A G
A61P A61P G01N C07K A01K A61P A61K G01N
inventional inventional additional inventional additional inventional additional additional
Yukio Takuya Masaaki Mika Mioko Tsukasa Yuka Taiji Chieko Michiko Yoshio
Shimomura Watanabe Mori Goto Harada Sugo Adachi Asami Kitada Abe Matsumoto