Millen White Zelano & Branigan, P.C.
Pyridone and aza-pyridone compounds and methods of use
Pyridone and aza-pyridone compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
Gilead Connecticut, Inc. Genentech, Inc.
A A A A A C A A A A A A C A A A A A A A A A A C A A C A A A A A A A C A A C C A C A A
A61P A61P A61K A61P A61P C07D A61P A61K A61P A61P A61P A61K C07D A61P A61P A61K A61P A61P A61P A61K A61P A61P A61K C07F A61P A61K C07D A61P A61K A61P A61P A61K A61P A61P C07D A61P A61P C07D C07C A61P C07D A61K A61P
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Daniel Zhongdong Ravi Jeffrey E. Wendy Peter A. Aaron C. Pavel E. Xiaojing Honglu Scott A. Kevin S. Antonio J. M. Jianjun Seung H.
Ortwine Zhao Krishnamoorthy Kropf Young Blomgren Schmitt Zhichkin Wang Zhang Mitchell Currie Barbosa Xu Lee