Fox Rothschild LLP
Tricyclic gyrase inhibitors
Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.
MERCK SHARP & DOHME CORP. LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
C C A A C C Y
C07F C07D A61K A61P C07D C07D Y02A
inventional inventional additional inventional inventional inventional additional
Zhiyong Sergio E. Daniel Felice C. Min Junhu Toan B. Suk Joong Douglas Leslie William John Allen John Xiaoming Michael Voon Thanh To
Chen Wong Bensen Lightstone Teng Zhang Nguyen Lee Phillipson Tari Finn Borchardt Li Trzoss Ong Lam