PROI Intellectual Property US
Dual-function starch-based composite nanoparticles as well as preparation method and application thereof
The present application discloses dual-function starch-based composite nanoparticles as well as a preparation method and application thereof. The preparation method comprises: hydrolyzing starch to form linear dextrin, grading the linear dextrin by using an alcohol-alcohol gradient precipitation method to obtain linear dextrin having homogeneous molecular weight distribution; oxidizing the linear dextrin by adopting an oxidation system to obtain oxidized dextrin; carrying out complex reaction on the oxidized dextrin and curcumin to form an oxidized dextrin-curcumin complex; and forming an oxidized dextrin-curcumin/chitosan hydrochloride composite nanoparticles from the oxidized dextrin-curcumin complex and chitosan hydrochloride. The aqueous phase solution of the dual-function starch-based composite nanoparticles containing gel polysaccharide is uniformly mixed with primary emulsion, calcium ion induction is carried out on the obtained double emulsion to obtain double-emulsion gel.
HEFEI UNIVERSITY OF TECHNOLOGY
A A A A A C A C A C A C
A61K A61K A61K A61K A61K C08L A61K C08B A61K C08L A61K C08B
additional inventional additional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Baocai Peijun Ran Xiaolong Yi Bao Wenjie Xiaomin
Xu Li Meng Li Pan Zhang Liu Li