Azetidine and piperidine compounds useful as PDE10 inhibitors
Azetidine and piperidine compounds of formula (I):as defined in the specification, compositions containing them, and processes for preparing such compounds and intermediates thereof. Provided herein also are methods of treating cognitive disorders or diseases treatable by inhibition of PDE10, such as Huntington's Disease, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
AMGEN INC.
A C A C A A C C A A C A A A A
A61P C07D A61K C07D A61K A61P C07D C07D A61P A61P C07D A61P A61P A61K A61P
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Michael J. Wenyuan Thomas T. Jian J. Matthew R. Alexander J. Jennifer R. Robert M. Wenge Qingyian
Frohn Qian Nguyen Chen Kaller Pickrell Allen Rzasa Zhong Liu