Spirocyclic hetercycle compounds useful as HIV integrase inhibitors
The present invention relates to Spirocyclic Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, X, Y, R1, R2 and R11 are as defined herein. The present invention also relates to compositions comprising at least one Spirocyclic Heterocycle Compound, and methods of using the Spirocyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.
Merck Sharp & Dohme Corp.
C A C C C C C A A A A A A A C C A
C07D A61K C07F C07D C07D C07D C07D A61P A61K A61K A61K A61K A61K A61K C07D C07D A61K
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John M. Yonglian Thomas G. Tao John S. Abbas M. Lihong Christine Ng Mark W. Paul J. Sherman T. Xuanjia Wensheng Thomas H. Ronald Dale
Sanders Zhang Steele Yu Wai Walji Hu Di Marco Embrey Coleman Waddell Peng Liu Graham Ferguson, II