Darby & Darby P.C.
N-substituted benzothiophenesulfonamide derivatives
The present invention relates to an N-substituted benzothiophenesulfonamide derivative or a pharmaceutically acceptable salt thereof and applications thereof. Furthermore, it provides an agent for preventing or treating cardiac or circulatory disease and so on caused by abnormal increase of production of angiotensin II or endothelin I based on chymase activity, or by activation of mast cell, and an agent for preventing adhesion after surgery, wherein the agent has a selective inhibitory action on chymase.
TOA EIYO Ltd.
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Shin-ichi Takahiro Atsuo Hidekazu Fumiya Takeshi Yusuke Hideki Shinji Akira Mizuo Tetsuo Shoji
Kazayama Morita Takahashi Masaki Yoneyama Hasegawa Mizuno Yamada Takai Tatsui Miyazaki Kuze Satoh