Johns Hopkins Technology Transfer
Conversion of chitin into N-acetylglucosamine, glucosamine and bioethanol
Compositions and methods are provided for converting chitin into N-acetylglucosamine, glucosamine and ethanol. The chitin may be used directly from the environment, for example, as occurs in invertebrate cuticles, fungal cells and/or algae. Mutant bacteria were created by knocking out or inactivating one or more genes preferably resulting in the chitin catabolic sensor maintaining an activated state. Methods are further provided for converting the N-acetylglucosamine into ethanol by means of a genetically engineered yeast strain which can be optionally co-cultivated with the Vibrionaceae to produce significant yields of ethanol.
New England Biolabs The Johns Hopkins University
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Y02E C12P C12P C12P C12N
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Xibing Donald Saul
Li Comb Roseman