Meunier Carlin & Curfman LLC
Macrocyclic compounds as TRK kinase inhibitors
Compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein ring A, ring B, W, m, R2, R2a, R3, R3a, and Z are as defined herein, are inhibitors of Trk kinases and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
Array BioPharma Inc.
A A C C A C A A A A C A Y C A A A
A61P A61P C07D C07D A61P C07D A61P A61P A61P A61P C07D A61K Y02A C07D A61P A61P A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional additional inventional inventional inventional inventional
Hong-Woon Gabrielle R. Jeongbeob Kevin Ronald Julia Steven W. Yutong Qian
Yang Kolakowski Seo Condroski Haas Andrews Jiang Zhao