Dock-and-Lock (DNL) Complexes for Disease Therapy
Disclosed herein are compositions and methods of use of dock and lock (DNL) complexes comprising a first antibody or fragment that binds to a stem cell antigen and a second antibody or fragment thereof that binds to an antigen on a diseased or damaged tissue or organ. The DNL complexes are of use for targeting stem cells to diseased or damaged organs or tissues and may be used to treat a variety of diseases or conditions that are responsive to stem cell therapy.
IBC Pharmaceuticals, Inc.
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A61P A61K B82Y C07K A61P C07K A61K C07K C07K C07K A61K C07K C07K C07K C07K C07K C07K A61P C07K C07K B82Y C07K B82Y C07K A61K A61K A61K C07K A61P C07K
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David M. Chien-Hsing
Goldenberg Chang