WPAT, P.C.
Method for synthesizing 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide or a derivative thereof
A method for synthesizing 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide or its derivatives has a step of introducing 6-chloro-6H-dibenz[c,e][1,2]oxaphosphorin or its derivative, an acid compound and water into a reacting chamber to form an organic layer having 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide or its derivative and an aqueous layer. Because the acid compound is from an external source and has a catalyzing effect, employing the method can prevent side reaction from occurring and increase yield of 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide or its derivative. Furthermore, the method is a one-pot operation of hydrolysis, dehydration and cyclization, so the method does not require purification of intermediates. Therefore, the method is time- and cost-saving and requires less organic solvent, resulting in less pollution to the environment.
UFC Corporation
C C
C07F C07F
inventional inventional
Yu-Chin Tien-Wen Yu-Cheng Kuan-Chieh Kai-Chiang Ling Chung-Ning
Lee Lo Lee Tseng Huang Lu Fan