J.C. Patents
Method for preparing active peptides from corn germ proteins
The present invention discloses a method for producing antihypertensive active peptides with corn germ protein as the material. The method comprises an alkali-heat treatment and continuous enzymolysis of the corn germ protein. The components with molecular weight less than 1000 Da in the active peptides obtained according to the present method account for more than 92%, and alanine-tyrosine (Ala-Tyr, AY) as the characteristic peptide fragments in the antihypertensive peptides accounts for more than 0.6%, so that the active peptides have a good ACE inhibitory activity in vitro as well as stability against temperature, pH and major gastrointestinal digestive enzymes, and have a significant effect of lowering blood pressure on spontaneous hypertension rats in vivo. The active peptides can be applied as a new functional nutrient to development and production of food, health food and pharmaceutical.
China National Research Institute of Food and Fermentation Industries
C A C A A A C
C12P A61K C07K A61P A61K A61P C07K
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Yaguang Weixue Muyi Yong Jun Wenying Lu Xingchang Zhentao Ruizeng Feng Zhe Liang Yongqing
Xu Yi Cai Ma Lu Liu Lu Pan Jin Gu Lin Dong Chen Ma