McDonnell Boehnen Hulbert & Berghoff LLP
Pyridopyrimidinone inhibitors of PIM-1 and/or PIM-3
Compounds of formula (I), useful for inhibiting PIM-I and/or PIM-3: and pharmaceutically acceptable salts thereof, wherein Y, Z, R1, R3, Q, X and R4 are as defined above. Pharmaceutical compositions and methods of treating diseases and conditions, such as cancer, are also disclosed.
Exelixis, Inc.
C C C C C C A C C A C C C C C
C07D C07D C07D C07D C07D C07C A61P C07D C07D A61P C07D C07D C07C C07D C07D
inventional inventional inventional inventional inventional additional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Patrick S. David Elena S.
Kearney Brown Koltun