Saliwanchik, Lloyd & Eisenschenk
Synthetic ion channels
Provided herein are self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. Further, provided are methods of treating or preventing conditions and diseases that are related to the dysfunction of ion channels, including chloride channels.
THE UNIVERSITY OF HONG KONG
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Xiang Huiyan Dan
Li Zha Yang