Wenderoth, Lind & Ponack, L.L.P.
Carboxylic acid derived benzoxazines as agents for the treatment of respiratory diseases
The present invention relates to a compound of formula (I)(wherein all symbols have the same meanings as described hereinbefore). The compound antagonizes cysLT2 and therefore, it is useful as an agent for the prevention and/or treatment of respiratory diseases such as bronchial asthma, bronchial asthma, chronic obstructive pulmonary disease, pneumonectasia, chronic bronchitis, pneumonia (e.g. interstitial pneumonitis etc.), severe acute respiratory syndrome (SARS), acute respiratory distress syndrome (ARDS), allergic rhinitis, sinusitis (e.g. acute sinusitis, chronic sinusitis, etc.), and the like, or as an expectorant or antitussives.
Ono Pharmaceutical Co., Ltd.
C A C A C A A C A
C07C A61P C07D A61P C07C A61P A61K C07D A61K
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Shinya Tadashi Jun Manabu Yoshisuke Satoshi
Takahashi Tatsumi Takeuchi Fujita Nakayama Itadani