Gavrilovich, Dodd & Lindsey LLP
Pharmaceutical composition for the prevention or treatment of a neurodegenerative disease, comprising a Daphne genkwa extract or a compound isolated therefrom
The present invention relates to: a pharmaceutical composition or a Nurr1 activating composition for the prevention or treatment of a neurodegenerative disease or a disease induced by impaired Nurr1 function, wherein the composition comprises an active ingredient in the form of genkwanin N or yuanhuacine, a Daphne genkwa extract comprising one or more of the above compounds, or a fraction thereof; or a functional food additive for preventing or alleviating a neurodegenerative disease or a disease induced by impaired Nurr1 function, wherein the additive comprises genkwanin N or yuanhuacine, a Daphne genkwa extract comprising one or more of the above compounds, or a fraction thereof; and a method for the prevention or treatment of a neurodegenerative disease or a disease induced by impaired Nurr1 function, wherein the method comprises the step of administering the pharmaceutical composition.
Korea Research Institute of Bioscience and Biotechnology
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A61P A61P A61K A61K
inventional inventional inventional inventional
Hoe Yune Yu Jin Kwang Soo Chun Hyung Won Gon Baek Soo Young Mi Mi Jin Kyoung Shim
Jung Kim Kim Kim Kim Han Kang Sohn Kim