Hovey Williams LLP
Gene encoding FHB1 resistance to Fusarium Head Blight disease and uses thereof
A protein conferring resistance to Fusarium Head Blight disease (FHB) is described, along with the DNA sequence of the corresponding gene and mRNA copy (cDNA). The cDNA of Fhb1 gene can be used to produce genetically-modified plants having increased resistance to FHB, particularly in wheat, barley and other plants affected by the disease. The protein has antifungal properties and inhibits fungal growth, thereby providing a means for reducing DON toxin in grains. Conserved functional domains are identified in the protein. Genetically-modified plants having increased resistance FHB are also described, along with methods for producing such genetically-modified plants.
Regents of the University of Minnesota Kansas State University Research Foundation
C C A
C12N C07K A01H
inventional inventional inventional
Bikram Nidhi Eduard Michael Sixin James A.
Gill Rawat Akhunov Pumphrey Liu Anderson