Moore & Van Allen, PLLC
N-acetylglucosamine-2-epimerase and method for producing CMP-neuraminic acid using the same
The present invention relates to a novel N-acetylglucosamine-2-epimerase and a method for preparing CMP-N-acetylneuraminic acid, more specifically, relates to a N-acetylglucosamine-2-epimerase derived from Bacteroides fragilis NCTC 9343, and a method for preparing CMP-N-acetylneuraminic acid using said N-acetylglucosamine-2-epimerase. According to the present invention, CMP-N-acetylneuraminic acid can be produced economically in a large amount through a one-step reaction using cytidine monophosphate and N-acetyl-D-glucosamine which are inexpensive substrates.
Gene Chem, Inc.
C C
C12P C12N
inventional inventional
Young Soo Kyoung Soon Dea Hee Won Min Sun Youp In Kang Sang Hee Byung Gee Tae Geon Jin Suk Jae Kyung Ji Young
Jung Jang Kim Seo Kang Hur Shim Kim Gil Woo Sohng Yang