McDermott Will & Emery LLP
Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
This invention provides compounds of formula Iwhere the dashed line represents an optional double bond;where R1 is phenyl, naphthyl, pyridyl, pyrimidyl, pyrrolyl, imidazolyl, pyrazyl, furyl, thienyl, oxazolyl, isoxazolyl, thiazolyl, or isothiazolyl, optionally substituted, and other substituents are defined herein. Such compounds are potassium channel modulators.
Valeant Pharmaceuticals International
C C A A
C07D C07D A61P A61P
inventional inventional inventional inventional
Huanming Jean-Michel Jianlan
Chen Vernier Song