Sughrue Mion, PLLC
Ethinyl-pyrazole derivative
Provided is a novel compound represented by formula [I] or a pharmaceutically acceptable salt thereof having antagonistic activity against group II metabolism-type glutamic acid (m-Glu) receptors. The compound or pharmaceutically acceptable salt thereof is useful as a prophylactic or therapeutic agent for diseases such as new mood disorders (depressive and bipolar disorders), anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, post-traumatic stress disorder, specific phobias, and acute stress disorder), schizophrenia, Alzheimer's disease, cognitive dysfunction, dementia, drug dependence, convulsions, tremors, pain, sleep disorders, and the like.
Taisho Pharmaceutical Co., Ltd.
C C C C A C A C C C C A A A C A A A A C
C07D C07D C07D C07D A61P C07D A61P C07D C07D C07D C07D A61P A61P A61P C07D A61P A61P A61P A61P C07D
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Akito Kumiko Seiji Hiroshi Toshio Kanako Yohei Hiroshi Tsuyoshi Kazunari Kazuhide
Yasuhara Okada Masuda Kawamoto Nakamura Yamamoto Matsuda Ohta Shibata Sakagami Konishi