Panitch Schwarze Belisario & Nadel LLP
Oxa spiro derivative, preparation method therefor, and applications thereof in medicines
The present invention relates to an oxa spiro derivative, a preparation method therefor, and applications thereof in medicines. Particularly, the present invention relates to an oxa spiro derivative represented by formula (I), a preparation method therefor, and a pharmaceutical composition comprising the derivative, applications thereof as an MOR receptor agonist, and applications in the preparation of drugs for treating and/or preventing pains and pains-related diseases. Substituent groups in the formula (I) are same as definitions in the specification.
Shanghai Hengrui Pharmaceutical Co., Ltd. Jiangsu Hengrui Medicine Co., Ltd
A A C C C
A61P A61K C07D C07D C07D
inventional inventional inventional inventional inventional
Feng Mingxun Binqiang Weikang Piaoyang Tao Yang Xin
He He Feng Tao Sun Liu Chen Li