NSIP Law
Pharmaceutical composition for preventing or treating allergic diseases such as asthma or atopy including baicalein as active ingredient
The present invention relates to a pharmaceutical composition for preventing or treating allergic diseases such as asthma or atopy including baicalein as an active ingredient. Baicalein is capable of regulating thymic stromal lymphopoietin-mediated signal transduction. The pharmaceutical composition of the present invention can effectively suppress inflammatory responses of allergic or asthmatic diseases due to the presence of baicalein extracted from Scutellariae Radix that regulates TSLP-mediated intracellular signal transduction to inhibit intracellular phosphorylation of STATS and inhibit the binding of TSLP to TSLPR. In addition, the pharmaceutical composition of the present invention may further include one or more compounds having synergistic effects with baicalein. In this case, the pharmaceutical composition can more effectively suppress inflammatory responses of allergic diseases such as asthma or atopy.
Azcuris Co., Ltd.
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A61K A61K A61K A61K
inventional inventional inventional inventional
Kiho Yong Woo Ki Yong Young Ho Youngjoo
Lee Jung Lee Jeon Byun