Novick, Kim & Lee, PLLC
Benzimidazole derivatives and preparation process and pharmaceutical uses thereof
The invention belongs to the technical field of pharmaceutical chemistry, and particularly pertains to benzimidazole derivatives, and preparation process and pharmaceutical uses thereof. Benzimidazole derivatives include Ligustrazine and NO donor derivatives. The kind of the compounds can rapidly release Ligustrazine or No in vivo, so that they can produce effective synergetic effects with Azilsartan, to enhance the anti-hypertension effect, and reduce adverse effects, and the released Ligustrazine can produce ideal protection to patients' livers and kidneys, thereby filling blanks in the prior art.
WUHAN QR PHARMACEUTICALS CO., LTD WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD
C C A C A A A A A C A C
C07D C07D A61K C07D A61K A61P A61P A61P A61P C07D A61K C07D
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Guangya Jian Chaodong Jianyi Wei
Xiang Ge Wang Ma Wang