Method for improving acid tolerance of Propionibacterium acidipropionici 
The invention provides a simple and effective method for improving acid tolerance of P. acidipropionici by adding arginine and/or aspartic acid to the culture medium. The acid tolerance of P. acidipropionici was improved by 60% and 20% respectively through adding arginine or aspartic acid into the culture medium. Consequently, PA production was improved by 36% and 26%, respectively. The maximal PA production was obtained by adding both 20 mM arginine and 20 mM aspartic acid. This method can be applied to large scale production of PA.
Jiangnan University
C
C12P
inventional
Guocheng Jianghua Ningzi Jian Long
Du Li Guan Chen Liu