McCarter & English, LLP
Methods of preparation of conjugates
The present invention is directed to methods of preparing a conjugate of a cell-binding agent and a drug (such as a cytotoxic compound). The methods comprise the use of an imine reactive compound to enable efficient conjugations of cytotoxic compounds with cell binding agents.
IMMUNOGEN, INC.
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Rajeeva Wei Michael Louis Nathan Elliott
Singh Li Miller Fishkin