Banner & Witcoff, Ltd.
Pegylated artesunate derivative, pharmaceutical composition and use thereof
A pegylated artesunate derivative, a pharmaceutical composition and uses thereof, the pegylated artesunate derivative is represented by the general formula (I):The pegylated artesunate derivative has activity comparable to that of artesunate, increased water solubility and stability, and an extended half-life in vivo.
Institute of Pharmacology and Toxicology Academy of Military Medical Science P.L.A. CHINA KPC Pharmaceuticals, Inc.
A C A Y A A A C C
A61P C08G A61K Y02A A61K A61K A61K C08L C08G
inventional inventional inventional additional inventional inventional inventional additional inventional
An Junwen Jia Qiyan Sicheng Qingbin Jinfeng Na Hui Jiufeng Xiaoyang Yuanjun
Xu Mao Liu Jia Li Meng Li Xing Liu Yan Shen Liang