Kilpatrick Townsend & Stockton LLP
Biomarker for gastric cancer
The present invention provides a method for diagnosing and determining prognosis of gastric cancer in a subject by detecting suppressed expression of the BCL6B gene, which in some cases is due to elevated methylation level in the genomic sequence of this gene. A kit and device useful for such a method are also provided. In addition, the present invention provides a method for treating gastric cancer by increasing BCL6B gene expression or activity.
The Chinese University of Hong Kong
C A C C A G
C12Q A61K C12Q C12Q A61P G01N
inventional inventional additional additional inventional inventional
Joseph Jao Yiu Jun Lixia Xiaoxing
Sung Yu Xu Li