Darby & Darby
N-substituted benzothiophenesulfonamide derivatives
The present invention relates to an N-substituted benzothiophenesulfonamide derivative or a pharmaceutically acceptable salt thereof and applications thereof. Furthermore, it provides an agent for preventing or treating cardiac or circulatory disease and so on caused by abnormal increase of production of angiotensin II or endothelin I based on chymase activity, or by activation of mast cell, and an agent for preventing adhesion after surgery, wherein the agent has a selective inhibitory action on chymase.
Toa Eiyo Ltd.
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Takeshi Hidekazu Shoji Shin-ichi Yusuke Mizuo Fumiya Takahiro Akira Shinji Hideki Atsuo Tetsuo
Hasegawa Masaki Satoh Kazayama Mizuno Miyazaki Yoneyama Morita Tatsui Takai Yamada Takahashi Kuze