Crowell & Moring LLP
4-(methyl sulfonyl amino) phenyl analogues as vanilloid antagonist showing excellent analgesic activity and the pharmaceutical compositions comprising the same
4-(methylsulfonylamino)phenyl analogues as potent vanilloid receptor antagonists and pharmaceutical compositions comprising the same. The compounds are useful as analgesics to prevent, alleviate or treat pain diseases or inflammatory disease including pain, acute pain, chronic pain, neuropathic pain, post-operative pain, migraine, arthralgia, neuropathies, nerve injury, diabetic neuropathy, neurodegeneration, neurotic skin disorder, stroke, urinary bladder hypersensitiveness, irritable bowel syndrome, a respiratory disorder such as asthma or chronic obstructive pulmonary disease, irritation of skin, eye or mucous membrane, fervescence, stomach-duodenal ulcer, inflammatory bowel disease, inflammatory disease and urgent urinary incontinence.
Gruenenthal GmbH
C A C A A A C C A A C A A A A A A A C C
C07C A61P C07C A61P A61P A61P C07C C07C A61P A61P C07C A61P A61P A61P A61P A61P A61P A61P C07C C07D
additional inventional inventional inventional inventional inventional additional additional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Hyun Kyung Young Ho Jee Woo Hee Hee Jin
Choi Kim Lee Kim Ha