Quinolinone derivatives as inhibitors of c-fms kinase
The invention is directed to compounds of Formulae I and II:wherein R1, R2, R3, R5, R6, Y1, Y2, Y3, Y4 and X are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase.
Janssen Pharmaceutica N.V.
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Mark R. Jinsheng Carl R. Jian Raymond Joseph Wing Sanath Mark J. Davoud
Player Chen Illig Liu Patch Cheung Meegalla Wall Asgari