Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders
The present invention provides compounds useful, for example, for modulating insulin levels in a subject, having the general formula I:wherein Q is an optionally substituted phenyl; L is a bond or O; P is a benzene or an optionally substituted thiazole ring; and R1 has the values provided herein. The present invention also provides compositions, uses, and methods for use of the compounds, for instance, for treatment of type II diabetes.
Amgen Inc.
C C A C C C A C C A C
C07D C07D A61P C07D C07D C07B A61P C07C C07D A61P C07D
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Jiwen Ying Michael J. Julio C. Yingcai Rajiv Zhihua Liusheng Jonathan
Liu Sun Schmitt Medina Wang Sharma Ma Zhu Houze