Holtz, Holtz, Goodman & Chick PC
1,2,3,4-tetrahydroquinoxaline compounds having glucocorticoid receptor binding activity
A 1,2,3,4-tetrahydroquinoxaline compound represented by the following formula:In the formula (1), R1 represents substituents such as a halogen, an alkyl, a cycloalkyl, an aryl or a heterocyclic group; p represents 0 to 5; R2 represents substituents such as a halogen, an alkyl, a hydroxyl or an alkoxy group; q represents 0 to 2; R3 represents substituents such as hydrogen, an alkyl, an alkenyl, an alkylcarbonyl or an arylcarbonyl group; R4 and R5 independently represent substituents such as hydrogen, a halogen, an alkyl, an alkenyl, an alkynyl, a cycloalkyl, an aryl or a heterocyclic group; R6 represents substituents such as hydrogen, an alkyl, an alkenyl, an alkynyl, a cycloalkyl, an aryl or a heterocyclic group; A represents an alkylene; R7 represents OR8, NR8R9, SR8, S(O)R8, S(O)2R8; R8 and R9 independently represent substituents such as hydrogen, an alkyl or an alkenyl; and X represents O or S.
Santen Pharmaceutical Co., Ltd.
C C C C C A C A A C C A A A A A C C
C07D C07D C07D C07D C07D A61P C07D A61P A61P C07D C07D A61P A61P A61P A61P A61P C07D C07D
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Masato Sachiko Miwa Masatomo Kenji Minoru Toshiyuki Mamoru
Nagatsuka Kobayashi Takai Kato Kawashima Yamamoto Mori Matsuda