Pyrimido compounds having antiproliferative activity
Disclosed are novel pyrimido compounds that are selective inhibitors of both KDR and FGFR kinases. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer.
Hoffmann-la Roche Inc.
A C
A61P C07D
inventional inventional
Christophe Apostolos Kin-Chun Pamela Loreen Jin-Jun Yi
Michoud Dermatakis Luk Rossman Liu Chen