Patent 360
Electro spun nanofibrous wound dressing and a method of synthesizing the same
The various embodiments herein provide an electro spun wound dressing comprising three nano fibrous layers and a method of synthesizing the same. The outer polymeric layer acts as a support layer for the other two layers and is hydrophilic in nature. The middle layer comprises a genipin cross linked reservoir layer loaded with a herbal extract of Melilotus officinalis and is hydrophobic or hydrophilic in nature. The second layer is cross-linked to control a release of the Melilotus officinalis extract in an aqueous environment. The third layer is a wound contacting inner layer comprising a non-cross-linked chitosan based nanofibrous layer that is hydrophilic in nature. Various additives are provided to enhance the mechanical or the chemical properties of the wound dressing and to control a release profile of the herbal extract.
A A A A A A D A A A A A A A A
A61L A61L A61F A61K A61F A61F D04H A61F A61L A61L A61K A61F A61K A61F A61F
inventional additional inventional inventional inventional inventional inventional inventional additional inventional inventional inventional inventional inventional inventional
Saeed Reza Faridi Esmaeil Seyed Mehdi
Sarkar Majidi Mirzaei Rezayat