Millen, White, Zelano & Branigan, P.C.
Pyridone and aza-pyridone compounds and methods of use
Pyridone and aza-pyridone compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
Gilead Connecticut, Inc. Genentech, Inc.
A A A A C A A C C A A A C A A A A A C A A A A A A C A A A C C A A A A A A A A A A A A
A61P A61P A61K A61P C07D A61P A61K C07F C07D A61P A61P A61P C07D A61K A61P A61P A61P A61P C07D A61P A61P A61P A61P A61K A61P C07D A61P A61P A61P C07C C07D A61K A61K A61K A61P A61P A61P A61P A61P A61P A61K A61K A61K
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Zhongdong Honglu Jeffrey E. Ravi Pavel E. Kevin S. Scott A. Aaron C. Seung H. Wendy Peter A. Daniel Antonio J. M. Jianjun Xiaojing
Zhao Zhang Kropf Krishnamoorthy Zhichkin Currie Mitchell Schmitt Lee Young Blomgren Ortwine Barbosa Xu Wang