Hodgson Russ LLP
Method for testing the degradation of polymeric materials
The present invention provides a novel method for monitoring the surface concentration of a drug in a polymer blend matrix and the reaction kinetics of the biodegradable polymers. Detailed information on surface concentration, degradation rates, degradation kinetics and mechanism, is provided by using Time-of-Flight Secondary Ion Mass Spectrometry (ToF SIMS) measurements. Also provided is a method for determining oligomers in hydrolyzed biodegradable polymers.
The Research Foundation of State University of New York
H Y Y G
H01J Y10T Y10T G01N
inventional additional additional inventional
Joseph A. Jiaxing Norma L. Joo-Woon
Gardella, Jr. Chen Hernandez de Gatica Lee