Kilpatrick Townsend & Stockton LLP
Cyanine dyes and methods of use
The present invention provides for cyanine dyes as near IR quenchers. The cyanine dyes have absorption wavelengths in the near-infrared region of about 650-900 nm and are essentially non-fluorescent. The dyes of the invention have at least one linking group. The present invention also provides substantially non-fluorescent, NIR probes. Biological assays based on these novel, substantially non-fluorescent, NIR probes are also provided.
Li-Cor, Inc.
G G C C
G01N G01N C09B C09B
inventional inventional inventional inventional
Charles Xinshe Daniel R. Jiyan Garrick M. Xinzhan William M.
Prescott Xu Draney Chen Little Peng Volcheck