Indolinone derivatives as protein kinase/phosphatase inhibitors
The present invention relates to certain 2-indolinone compounds which modulate the activity of protein kinases (“PKs”) and phosphatases. The compounds of this invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.
Sugen, Inc.
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G. Davis Xiaoyuan Peng Cho
Harris Li Tang