Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
Process for producing alpha-aminoketones
An amino group of an &agr;-amino acid ester is protected as an imine, and it is then reacted with a halomethyllithium to obtain an N-protected-&agr;-aminohalomethylketone. Further, this N-protected-&agr;-aminohalomethylketone is treated with an acid to obtain an &agr;-aminohalomethylketone. This process is suited for industrial production, and can produce an &agr;-aminohalomethylketone and its related compounds economically and efficiently.
Ajinomoto Co., Inc.
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Naoko Tomoyuki Kunisuke Takashi Masakazu
Hirose Onishi Izawa Nakano Nakazawa