Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
Process for the production of &agr;-human atrial natriuretic polypeptide
DNA fragments which contain a sequence of DNA which encodes a protective peptide-fused &agr;-hANP in which the protective peptide has a C-terminus lysine residue which is directly fused to the N-terminus of the &agr;-hANP, vectors which contain such a DNA sequence, and microorganisms transformed which such a vector are useful for the production of &agr;-hANP.
Fujisawa Pharmaceutical Co., Ltd.
C C C A C C C A
C07K C07K C07K A61P C12N C07K C07K A61P
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Mineo Yoshinori Yoshimasa Hisashi Ikuo
Niwa Ishii Saito Yamada Ueda