Lucas & Mercanti, LLP
2-phenylbenzofuran derivatives, method for preparing the same and use of the same for treating inflammatory disease
The present invention relates to a novel 2-phenylbenzofuran derivative or a pharmaceutically acceptable salt thereof, a production method for the same, and a pharmaceutical composition for preventing or treating an inflammatory disease comprising the same as an active ingredient, and the novel 2-phenylbenzofuran derivative or the pharmaceutically acceptable salt thereof according to the present invention is outstandingly effective in suppressing NO, IL-6, and TNF-alpha induced by macrophages, and therefore can advantageously be used in a pharmaceutical composition for preventing or treating an inflammatory disease.
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY DONGGUK UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
C A A A A C C C C
C07D A61K A23V A61K A23L C07D C07D C07D C07D
inventional inventional additional inventional inventional inventional inventional inventional inventional
Kyung Seop Ok-Kyoung Xuezhen Doo-Young Hyung Won Kyeong Sei-Ryang Jung Hee
Ahn Kwon Xu Kim Ryu Lee Oh Kim