Fish & Richardson P.C.
Macrocyclic compounds as TRK kinase inhibitors
Compounds of Formula I: and pharmaceutically acceptable salts thereof, wherein ring A, ring B, W, m, D, R2, R2a, R3, R3a, and Z are as defined herein, are inhibitors of Trk kinases and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
Array BioPharma Inc.
C C C A C A A A C A A A A A A Y A
C07D C07D C07D A61P C07D A61P A61P A61P C07D A61P A61P A61P A61P A61P A61P Y02A A61K
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional additional inventional
Jeongbeob Steven W. Julia Gabrielle R. Hong-Woon Yutong Kevin Ronald Qian
Seo Andrews Haas Kolakowski Yang Jiang Condroski Zhao