Fish & Richardson P.C.
Chimeric antigen receptor that binds HLA-DR and CAR-T cell
The present invention relates to an antigen-binding molecule comprising a heavy chain variable region comprising a heavy-chain complementarity-determining region 1 (HCDR1) comprising an amino acid sequence represented by Sequence No. 1, an HCDR2 comprising an amino acid sequence represented by Sequence No. 2, and an HCDR3 comprising an amino acid sequence represented by Sequence No. 3; a light-chain variable region comprising a light-chain complementarity-determining region 1 (LCDR1) comprising an amino acid sequence represented by Sequence No. 4, an LCDR2 comprising an amino acid sequence represented by Sequence No. 5, and an LCDR3 comprising an amino acid sequence represented by Sequence No. 6; wherein the antigen-binding molecule is a T cell receptor (TCR); and to a cell line expressing the same.
Eutilex Co., Ltd.
C C A C C C A C A C A C C C C C C C C A A
C07K C12N A61K C07K C12N C07K A61K C07K A61K C07K A61K C07K C07K C12N C07K C07K C07K C07K C07K A61P A61K
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Jung Yun Hyun Tae Kwang Hee Sun Woo Eun Hye Young Gyoon Ji Won Byoung S. Jin Kyung Bo Rim Seung Hyun Young Ho
Lee Son Kim Im Yoo Chang Chung Kwon Choi Yi Lee Kim