MacMillan, Sobanski & Todd, LLC
Arene connected polyamine macrocyclic derivatives, preparation methods and pharmaceutical uses thereof
The present invention relates to arene connected polyamine macrocyclic derivatives represented by general formula I, pharmaceutically acceptable salts or hydrates thereof which have anti-HIV activities, in which the definitions of substituents are as defined in the description; to preparation methods of the compounds of formula I; to pharmaceutical compositions containing the compounds of formula I or their pharmaceutically acceptable salts or hydrates; to the use of the compounds of formula I or their pharmaceutically acceptable salts or hydrates for the preparation of a medicament for the treatment and prevention of HIV-associated diseases.
Beijing Molecule Science and Technology Co., Ltd.
C C A C C
C07D C07D A61P C07D C07D
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Hongying Guoming Xiaokui Wu Jing Lili Song Xingzhou Junhai Xinbo Yunde Zhibing Yao
Liu Zhao Wang Zhong Su Wang Li Li Xiao Zhou Xie Zheng Liu