McDonnell Boehnen Hulbert & Berghoff LLP
6-phenylpyrimidinones as PIM modulators
A compound having Formula I or II (Formula I) or (Formula II), or a pharmaceutically acceptable salt thereof, wherein X, Z, R1, R2, R11 and R12 are as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.
Exelixis, Inc.
C C C C C C C C A A C
C07D C07D C07D C07D C07D C07D C07D C07D A61P A61P C07D
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Brian Amy L. Michael Naing Wei S. David Ping Wai Ki Vicky Patrick Elena S. Moon Hwan Peiwen Hongwang
Kane Tsuhako Pack Aay Xu Brown Huang Chan Kearney Koltun Kim Zhou Du