Wenderoth, Lind & Ponack, L.L.P.
Substituted indole derivatives for the treatment of respiratory diseases
The present invention relates to a compound of formula (I)(wherein all symbols have the same meanings as described hereinbefore). The compound antagonizes cysLT2 and therefore, it is useful as an agent for the prevention and/or treatment of respiratory diseases such as bronchial asthma, bronchial asthma, chronic obstructive pulmonary disease, pneumonectasia, chronic bronchitis, pneumonia (e.g. interstitial pneumonitis etc.), severe acute respiratory syndrome (SARS), acute respiratory distress syndrome (ARDS), allergic rhinitis, sinusitis (e.g. acute sinusitis, chronic sinusitis, etc.), and the like, or as an expectorant or antitussives.
Ono Pharmaceutical Co., Ltd.
C A A A A C C A C
C07C A61K A61P A61P A61P C07D C07D A61K C07C
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Shinya Satoshi Yoshisuke Manabu Tadashi Jun
Takahashi Itadani Nakayama Fujita Tatsumi Takeuchi