Howard & Howard Attorneys PLLC
Acrylamide compounds and use thereof for inhibiting apoptosis
The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate of the compound, and to a composition comprising the compound of Formula I, or the isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluents. The present invention also relates to use of the compound of Formula I, or the isomer, pharmaceutically acceptable salt and solvate thereof for combating apoptosis, preventing or treating a disease or disorder associated with apoptosis; and especially use for protecting cardiomyocyte, and for preventing or treating a disease or disorder associated with cardiomyocyte apoptosis.
CHINESE PLA GENERAL HOSPITAL
A A C C A A A A C A C A A A C A
A61P A61K C07D C07D A61K A61K A61K A61K C07D A61K C07D A61K A61K A61K C07C A61P
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Wei Juan Ruijun Junhai Jie Zhibing Wu Song Chunlei Kunlun Xin Jie Lili Guoliang Long
Li Liu Li Xiao Wang Zheng Zhong Li Liu He Li Tang Wang Hu Long