Hamilton, Brook, Smith & Reynolds, P.C.
Diaminoalkane aspartic protease inhibitors
Diaminoalkanes of Formula I have now been found which are orally active and bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with elevated levels of aspartic protease activity. The invention also relates to a method for the use of the compounds of Formula I in ameliorating or treating aspartic protease related disorders in a subject in need thereof comprising administering to said subject an effective amount of a compound of Formula I.
Vitae Pharmaceuticals, Inc.
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Alexey V. Zhenrong Salvacion Robert D. Patrick T. Jean-Pierre Gerard David A. Colin M. Suresh B. John J. Wei Jing Lawrence W.
Ishchenko Xu Cacatian Simpson Flaherty Wery McGeehan Claremon Tice Singh Baldwin Zhao Yuan Dillard