Sughrue Mion, PLLC
Pyrimidine-5-carboxamide derivatives
Pyrimidine-5-carboxamide derivatives represented by a general formula (I) or salts thereof [wherein each symbol has the following meaning;X: O, S, NR1, CO, NR1CO, CONR1, C&boxH;N&#8212;OR1 or a bond,Y: a lower alkylene group which may be substituted by OR1 or &#8212;NHR1, or a bond,Z: O, NR2 or a bond,A: H, or a lower alkyl which may have a substituent, a &#8212;CO-lower alkyl which may have a substituent, an aryl which may have a substituent, a heteroaryl which may have a substituent, a cycloalkyl which may have a substituent or a nitrogen-containing saturated heterocyclic group which may have a substituent,B: an aryl which may have a substituent or a heteroaryl group which may have a substituent,R1, R2: H, a lower alkyl or a &#8212;CO-lower alkyl group].
Yamanouchi Pharmaceutical Co., Ltd.
C C C A C C C C C C C C C C
C07D C07D C07D A61P C07D C07D C07D C07D C07D C07D C07D C07D C07D C07D
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Makoto Hiroyuki Akiko Souichirou Eiichi Akira Ryo Atsushi Kazuhito
Takeuchi Hisamichi Orita Kawazoe Nakai Toyoshima Naito Ichikawa Tanabe