Perkins Cole LLP
Cyanovirin variant-polymer conjugates
The present invention provides variants of cyanovirin-N and water-soluble polymer conjugates thereof. The cyanovirin-N of the invention are particularly suited for site-selective covalent attachment of one or more water soluble polymers, to provide polymer conjugates of cyanovirin-N variants exhibiting antiviral activity.
Nektar Therapeutics AL The Government of the United States of America as represented by The Secretary of The Department of Health and Human Services, The National Institutes of Health
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Michael J. Michael R. Toshiyuki M. Elizabeth Barry R.
Roberts Boyd Mori Snell O'Keefe