Edwards Wildman Palmer LLP
Macrocyclic hepatitis C serine protease inhibitors
The present invention relates to novel fluorinated macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient.
AbbVie, Inc.
C C A A A A C
C07K C07K A61K A61P A61P A61P C07K
inventional inventional additional inventional inventional inventional inventional
Liangjun Ming Timothy Keith F. Kevin Hui-Ju
Lu Yeung Middleton McDaniel Kurtz Chen