Genomics Institute of the Novartis Research Foundation
Compounds and compositions as protein kinase inhibitors
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, BCR-Abl, PDGF-R, trkB, c-SRC, BMX, FGFR3, b-RAF, ΣΓK, Tιε2, Λχκ, θNK2α2, MKK4, c-RAF, MKK6, SAPK2α and SAPK2β kinases.
IRM LLC
A A A A A A C C A A A A A A A A A A A A A A A A A A C A A A A C A A A A C
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Taebo Nathanael Schiander Qiong Pingda Guobao Pamela A. Greg Qiang Xia Shuli
Sim Gray Zhang Ren Zhang Albaugh Chopiuk Ding Wang You