Schmeiser, Olsen & Watts, LLP
Method for modulating a bacterial invasion switch
The subject matter disclosed herein pertains to the modulation of a bacterial invasion switch and the subsequent use of the bacterium to vaccinate an organism. In one embodiment, the bacterial invasion switch is modulated by changing the proteolysis of ExoR protein. In another embodiment, a mutated bacterium produces a mutant ExoR protein that resists proteolysis.
Research Foundation of the City University of New York
A C A A C A
A01H C12N A01N A61K C12N A01H
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Menghua Li Haiyang Shari Zahra Haiping
Yang Luo Lu Walcott Salehi Cheng