Agris & von Natzmer, LLP
Triazanonane derivatives or pharmaceutically acceptable salt thereof for enhanced fluorine-18 labeling
The present invention relates to a triazanonane derivative indicated by the chemical formula 1 below, or a pharmaceutically acceptable salt thereof, and a method for preparing same, and the triazanonane derivative according to the present invention forms a complex with a metal-fluoride and displays an effect of increasing the labeling efficiency up to 78-90% when labeling F-18, thus enabling use in various radioactive medicine labeling(In the chemical formula 1, R1, R2, A. E. X, n and m are as defined in the present description.)
Snur & DB Foundation
C A C
C07K A61K C07D
inventional inventional inventional
June-Key Dong Soo Jae Min Myung Chul Dinesh
Chung Lee Jeong Lee Shetty