Sterne, Kessler, Goldstein & Fox P.L.L.C.
Thiazole inner salt compounds, and preparation methods and uses thereof
The present invention pertains to field of pharmaceutical chemicals, and relates to thiazole inner salt compounds, preparation methods and uses thereof. Specifically, the present invention relates to a compound of Formula I, hydrates or pharmaceutically acceptable salts thereof. The compound of Formula I of the present invention is a potent cross-linking protein cleavage agent, has a stable structure, good physical and chemical properties, and good pharmacological activities, and is suitable for large scale production to obtain samples with stable, controllable and reliable quality, thereby being suitable for pharmaceutical development.
Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China
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Xinbo Shuang Wu Lili Zhibing Song Junhai
Zhou Cao Zhong Wang Zheng Li Xiao