Birch, Stewart, Kolasch & Birch, LLP
4,5,6,7-tetrahydro-[1,2]dithiolo[4,3-C] pyridine-3-thione compounds
The present invention relates to new compounds directly increasing kinase activity of p90 ribosomal S6 kinase 1 (RSK1), a pharmaceutical composition comprising them as active ingredient, a use thereof to prevent or treat hepatic fibrosis or cirrhosis, and a method for preventing or treating hepatic fiborsis or cirrhosis, comprising administering a therapeutically effective amount of the composition to mammal.
CJ Cheiljedang Corp.
C A A
C07D A61P A61P
inventional inventional inventional
Seung-Jin Eun-Young Mvong-Suk Sang-Geon Sang-Ho Jee-Woong Kwang-Do Jin-Wan
Lee Park Ko Kim Lee Lim Choi Kim