Sterne, Kessler, Goldstein & Fox P.L.L.C.
Oral pharmaceutical composition of Tecovirimat and preparation method thereof
The present invention relates to a pharmaceutical composition, comprising Tecovirimat, cyclodextrin and an additive, and optionally a pharmaceutically acceptable excipient. The present invention also relates to a method for preparing the pharmaceutical composition. The composition improves the solubility of Tecovirimat in water by using cyclodextrin and meglumine in combination, as compared with the solubility of Tecovirimat in water by using cyclodextrin or meglumine alone.
Institute of Pharmacology and Toxicology Academy of Military
 Medical Sciences P.L.A. China
A A A A A A A A B C A A C A
A61P A61K A61K A61K A61K A61K A61K A61K B82Y C08B A61K A61K C08L A61K
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Song Meiyan Wei Chunsheng Xinbo Yuli Wu
Li Yang Gong Gao Zhou Wang Zhong