Preparation of crystal form II of clarithromycin
 The present invention provides a process for the preparation of 6-O-methylerythromycin A Form II comprising converting erythromycin A to 6-O-methylerythromycin A and treating the 6-O-methylerythromycin A with a number of common organic solvents or mixtures of common organic solvents. 
Abbott Laboratories
C
C07H
inventional
David A. Jih-Hua
Riley Liu