Oblon, Spivak, McClelland, Maier & Neustadt, P.C.
Method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine
 A method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine, which comprises reacting 3-hydroxy-3-mercaptomethylquinuclidine or a salt thereof and a carbonyl compound in the presence of a catalyst made of at least one member selected from the group consisting of tin halides, oxyacids of phosphorus, phosphorus oxyhalides and organic sulfonic acids, to produce cis-form 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine or a salt thereof. 
Ishihara Sangyo Kaisha Ltd.
A C A
A61P C07D A61P
inventional inventional inventional
Tadashi Hayato Hiroshi Masahiko Tatsuo Takayoshi Koji Masaru Isamu Sho
Nakamura Ariyoshi Yoshizawa Sawaki Isogai Ando Hayashi Kimura Katsuyama Tokumoto