Birch, Stewart, Kolasch & Birch
Thiazole compounds, a process for preparing same and a pharmaceutical composition containing the thiazole compounds
 The present invention provides new thiazole compounds possessing immuno-modulating activity, i.e. thiazole compounds of the general formula (1): ##STR1## wherein R.sub.1 stands for a hydrogen or halogen atom or a lower alkyl, lower alkoxy, substituted or unsubstituted phenoxy, nitro or cyano group, R.sub.2 for a hydrogen atom or a lower alkyl or lower alkylthio group, and R for an .alpha.-halogenoalkyl group or the grouping: ##STR2## a process for preparing same and pharmaceutical compositions containing the thiazole compounds. More particularly, the present invention provides new thiazole compounds of the above general formula (1) which have immuno-modulating activity and are thus effective against immunodiseases such as chronic rheumatoid arthritis and also useful against viral diseases or for the immunotherapy of cancers, but show weak toxicity and are thus extremely desirous as medicines, a process for the preparation of the thiazole compounds and pharmaceutical compositions containing the thiazole compounds. 
Mitsui Toatsu Kaguku Kabushiki Kaisha
C C
C07D C07D
inventional inventional
Akira Seitaro Hiroshi Tatsuro Yutaka Isao Mikio Takuo Hiroshi
Awaya Kajiya Tokuda Yokoyama Okazaki Sakano Kumakura Nakano Kawazura