Biologically active complex and its preparation
A biologically active complex comprising either a polypeptide having the sequence of a variant of a naturally occurring protein, wherein said polypeptide is at least partially unfolded as compared to the said naturally occurring protein; or a peptide of up to 50 amino acids, for instance a fragment of the naturally occurring protein or a variant thereof; and a pharmaceutically acceptable salt of a fatty acid or lipid. The complexes of the invention demonstrate a novel mode of action, that gives rise to opportunities for the development of further active agents and screening methods.
HAMLET PHARMA AB
A C A C C A G G
A61P C07K A61K C12Q C07K A61K G01N G01N
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Chin Shing Catharina Maria Ann-Kristin Kenneth Hun Petter
Ho Svanborg Trulsson Mossberg Mok Storm