Arnold & Porter LLP
Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof
The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
Genentech, Inc.
C A G G C C G C
C07K A61K G01N G01N C12N C07K G01N C07K
inventional additional inventional additional additional additional additional inventional
Austin J. Christopher William I. Paul Colin Audrey
Gurney Grimaldi Wood Godowski Watanabe Goddard