Jones Day
Therapeutic agents useful for treating pain
A compound of formula:wherein A, Ar, R3, R6, and m are disclosed herein, or a pharmaceutically acceptable salt thereof (a “Cyanoiminopiperazine Compound”), compositions comprising an effective amount of a Cyanoiminopiperazine Compound, and methods for treating or preventing pain, urinary incontinence, an ulcer, inflammatory-bowel disease, irritable-bowel syndrome, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia or depression in an animal comprising administering to an animal in need thereof an effective amount of a Cyanoiminopiperazine Compound are disclosed.
Euro-Celtique S.A.
A C A A A A C A A A C A A A A A A A A A A C A C A C A C
A61P C07D A61P A61P A61P A61P C07D A61P A61P A61P C07D A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C07D A61P C07D A61P C07D A61P C07D
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Chongwu Xiaoming Donald J. Qun Laykea
Zhang Zhou Kyle Sun Tafesse