Panitch Schwarze Belisario & Nadel LLP
Crystal form of orexin receptor antagonist compound, and preparation method and application thereof
Disclosed is a preparation method of an orexin receptor antagonist compound 5-3. Crystalline forms I-IV of an orexin receptor antagonist compound 5-3 are provided. Also provided are processes of preparing crystalline forms of the orexin receptor antagonist compound 5-3, as well as methods of using the crystalline forms I-IV for treating an orexin-related disease.
SHANGHAI HAIYAN PHARMACEUTICAL TECHNOLOGY CO., LTD. YANGTZE RIVER PHARMACEUTICAL GROUP CO., LTD.
C A A A A A A
C07D A61K A61P A61P A61P A61K A61P
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Yuan Zhi Dakun Zheng Xiaolin Songliang Weidong Yuhe Haiying
Chen Luo Qin Wang Li Wu Li Wang He