Intellectual Property Connections, Inc.
In vivo assay for neurite outgrowth in zebrafish and its application in drug screening
A genetically modified zebrafish embryo, comprising a HBNF cDNA or a NGF cDNA or a GDNF cDNA together with a cDNA encoding green fluorescent protein (GFP) so as to induce neurite outgrowth during said zebrafish embryonic development, and a method of using such genetically modified zebrafish embryo to identify a therapeutic agent are disclosed.
Academia Sinica
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A01K C12N A01K A01K A01K A01K
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Chioh-Yueh Gen-Der I-Ching Chih-Ming Chang-Jen
Chen Chen Lu Chou Huang