McDonnell Boehnen Hulbert & Berghoff
Method for making freeze dried drug dosage forms
 The present invention discloses an improved technique for preparing a rapidly dispersing pharmaceutic tablet of a granular therapeutic agent which has both relatively low solubility and relatively large particle size. Xanthan gum is added to a liquid admixture of solvent, carrier components, and the granular therapeutic agent. The xanthan gum not only facilitates suspension of the granular therapeutic agent in the liquid admixture, but, more surprisingly, does so without adversely effecting the dispersion qualities and texture of the tablet in the patient's mouth upon administration. 
R.P. Scherer Corporation
A A
A61K A61P
inventional inventional
Sang K. Patrick
Wong Kearney