Lex IP Meister, PLLC
Pyridopyrimidinone compounds for modulating the catalytic activity of histone lysine demethylases (KDMs)
The present invention provides a compound of Formula (I) being capable of modulating the activity of histone lysine demethylase (KDM), pharmaceutical compositions thereof, methods to prepare the said compounds, and the use of such compounds as a medicament. The compound of Formula (I) acts as KDM inhibitor with marked potency, thereby having an outstanding potential for a pharmaceutical intervention of cancer and any other diseases related to KDM dysregulation.
DONG-A ST CO., LTD.
C A A A C A A A A A A A A A A A A A A A A A A A
C07D A61P A61P A61P C07D A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P
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Taesun Jun Gyu Hae-Sun Taeyoung Seung Min Myeong-seop
Park Kim Kim Yoon Yang Kim