Stewart and Kolasch, Ltd.
D-.alpha.-(4-hydroxypyridine-3-carbonamido)-p-hydroxyphenylacetamidopenic illanic acid
 Penicillins of the formula: ##SPC1## Wherein R is an unsubstituted phenyl group or a substituted phenyl group having one or more hydroxyl groups or a cyclohexadienyl group and A represents a monocyclic or polycyclic nitrogen-containing heterocyclic aromatic ring, which are useful as antimicrobial agents having a broad antimicrobial spectrum against gram-positive and gram-negative bacteria including Pseudomonas and can be produced advantageously from the phenacyl ester of 6-aminopenicillanic acid through a series of steps. 
Sumitomo Chemical Company, Limited
C C
C07D C07D
inventional inventional
Iwao Kozo Takenari Hisao Hirotada Norithiko
Nakatsuka Shimago Nakagome Tobiki Yamada Tanno