Muncy, Geissler, Olds & Lowe, P.C.
Biodegradable cross-linked polymer and methods of preparing the same
A biodegradable cross-linked polymer and methods of preparing same are provided. The biodegradable cross-linked polymer is formed from a biodegradable polymeric material having two or more arms, which is a random copolymer formed of a first monomer and a second monomer different from the first monomer. The first monomer is selected from the group consisting of L-lactide, DL-lactide, glycolid, ε-caprolactone, trimethylene carbonate, p-dioxanone, amino acid-derived polycarbonates and polyorthoesters. The second monomer is one or two selected from the group consisting of D-lactide, DL-lactide, glycolide, ε-caprolactone, trimethyl carbonate, salicylic acid, carbonates, amino acids and derivatives thereof. The biodegradable polymeric material has a molecular weight of from 5,000 to 1,200,000 and an intrinsic viscosity of from 0.1 to 9.0 dl/g. Each of the terminal groups on the arms of the biodegradable polymeric material is selected from the group consisting of hydroxyl amino and carboxyl groups.
Shanghai Microport Medical (Group) Co., Ltd.
C A C C A A A A C C A C C C A A
C08J A61F C08G C08G A61F A61F A61F A61L C08J C08J A61F C08G C08J C08J A61F A61L
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Yahong Wei Hongyan Qiyi Jing Juan
Kang Wang Jiang Luo Wang Hou