Fish & Richardson P.C.
Genetically modified non-human animal with human or chimeric PD-L1
Non-human animals, methods and compositions for making and using the same, are provided, wherein the non-human animals comprise a humanized programmed death-ligand 1 (PD-L1, PDL1, or B7-H1). Such non-human animals may be described, in some embodiments, as having a genetic modification to an endogenous PD-L1 gene so that the non-human animals express a humanized PD-L1 protein that includes a human portion and an endogenous portion (e.g., a non-human portion).
Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
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Chaoshe Xiaofei Yanan Yuelei Rui Yang
Guo Zhou Guo Shen Huang Bai