Foley & Lardner LLP
N-acetylglucosaminlytransferase and polynucleotide encoding the same
The present invention relates to an enzyme having novel N-acetylglucosaminyltransferase (OMGnT) activity, a polynucleotide encoding the enzyme, a recombinant polynucleotide comprising the polynucleotide, a host cell comprising the recombinant polynucleotide, a method for producing an enzyme protein having OMGnT activity by culturing the host cell in a medium, and a method for modifying a sugar chain structure with the enzyme and a carbohydrate having a sugar chain structure modified by the method. This enzyme enables the production of complex carbohydrates, which could not be formed with conventional glycosyltransferases.
National Institute of Advanced Industrial Science and Technology
C
C12N
inventional
Shigemi Aruto Hiroshi Makoto Tamao Yoshifumi Yasunori
Sugioka Yoshida Manya Takeuchi, deceased Endo Jigami Chiba