Substituted 3-amino-thieno [2,3-b]pyridine-2-carboxylic acid amide compounds and processes for preparing and their uses
Disclosed are compounds of formula (I): wherein R1 and R2 are defined herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
Boehringer Ingelheim Pharmaceuticals, Inc.
C A A A A A A A A A C A A A A A A A A A A C A A A A A A A A A
C08G A61P A61P A61P A61P A61P A61P A61P A61P A61P C07D A61P A61P A61P A61P A61P A61P A61P A61P A61P A61P C08G A61P A61P A61K A61P A61P A61P A61P A61P A61K
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Jonathan Zhidong Ronald John Jiang-Ping Daniel Richard Sanxing Eugene Peter Weimin Ming-Hong Tina Roman Wolfgang Charles L.
Emeigh Chen Sorcek Wu Marshall Sun Hickey Nemoto Liu Hao Morwick Fleck Cywin