Hamilton, Brook, Smith & Reynolds, P.C.
Piperidine and morpholine renin inhibitors
Described are compounds which are orally active and bind to renin to inhibit its activity. They are useful in the treatment or amelioration of diseases associated with renin activity. Also described are methods of use of these compounds for treating or ameliorating a renin mediated disorder in a subject.
Vitae Pharmaceuticals, Inc.
C C A
C07D C07D A61P
inventional inventional inventional
Salvacion Lawrence W. Wei Jing Robert D. Alexey V. Zhenrong Colin M. Suresh B. Gerard David A. John J.
Cacatian Dillard Zhao Yuan Simpson Ishchenko Xu Tice Singh McGeehan Claremon Baldwin