JHK Law
Composition for treating immune diseases containing daurinol compound as active ingredient
The daurinol compound according to the present invention exhibits excellent therapeutic effects on arthritis and inflammatory bowel diseases by having an excellent activity in inhibiting the generation of IL-17 and TNF-α, which are inflammatory cytokines causing inflammation, and can alleviate transplant rejection by inhibiting the proliferation of alloreactive T cells and increasing regulatory T cells; therefore, the daurinol compound according to the present invention can be used as a pharmaceutical composition capable of treating and preventing immune diseases. In addition, being a natural substance derived from the Mongolian medicinal plant Haplophyllum dauricum or Haplophyllum cappadocicum, the daurinol compound according to the present invention does not cause cytotoxicity and thus may be used as a composition for a functional health food capable of preventing and remedying immune diseases.
THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CATHOLIC UNIV. OF KOREA SONGEUI CAMPUS
A A A
A61K A61P A61K
inventional inventional inventional
Min-Jung Hye-Jin Eun Ji Sung-Hee Jae-Kyung Dong-Yun Seon-Yeong Mi-La Eun Kyung Eun-Jung
Park Son Yang Lee Kim Shin Lee Cho Kim Lee