Locke Lord LLP
Device for detecting a dynamical network biomarker, method for detecting same, and program for detecting same
The present invention provides a device, method, and program for detection of a biomarker candidate that may be used in a diagnosis of a pre-disease state indicating a transition from a healthy state to a disease state. Biological samples are collected from a subject to be measured at different times. Statistical data is obtained by aggregating measurement data obtained in measurement on collected biological samples. Thereafter, a process of obtaining high-throughput data (s1), a process of choosing differential biological molecules (s2), a process of clustering (s3), a process of choosing a DNB candidate (s4), and a process of identifying a DNB by significance analysis (s5) are carried out.
Japan Science and Technology Agency
G G G G G
G16B G16B G16B G16B G16B
inventional inventional inventional inventional additional
Rui Zhiping Luonan Meiyi Kazuyuki
Liu Liu Chen Li Aihara