Fish & Richardson P.C.
IFN-gamma-inducible regulatory T cell convertible anti-cancer (IRTCA) antibody and uses thereof
Provided are IFN-γ-Inducible Regulatory T Cell Convertible Anti-Cancer (IRTCA) antibodies and antigen-binding fragment thereof that bind to an activation-inducible TNFR (AITR) polypeptide. Various in vitro and in vivo methods and compositions related to IRTCA antibodies described herein are also provided. Methods include, for example, changing cytokine secretion from T cells in vivo or in vitro and prevention and/or therapeutic treatment of cancer using an IRTCA antibody or fragment thereof.
Eutilex Co., Ltd.
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G01N A61K G01N C07K G01N A61K C07K A61P A61K C07K C07K C07K A61P C07K A61P C07K C07K C07K A61K C07K A61P C07K C07K G01N
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Seunghyun Byoung S Seoung-Joo Joong Won
Lee Kwon Lee Lee