Fitzpatrick, Cella, Harper & Scinto
Method for specimen measurement
 In a method for measuring a specified component in a specimen by reacting the specimen with a first reagent formed by binding a substance active to the specified component, with carrier particles and a second reagent formed by labelling a substance active to the specified component with a first label, and measuring the substances in the complexes obtained in the reaction, there is disclosed a method featured by labelling the carrier particles with a second label different from the first label, and detecting the second label and then the first label utilizing the detection of the second label as a trigger. This method enables a highly precise measurement without the influence of noise components in the detection of specified trace components in the specimen, utilizing an antigen-antibody reaction or a nucleic acid hybridization. 
Canon Kabushiki Kaisha
Y G Y Y Y G Y Y
Y10S G01N Y10S Y10S Y10S G01N Y10S Y10S
additional inventional additional additional additional inventional additional additional
Matsuomi Hidehito Takeshi Kazumi Toshikazu
Nishimura Takayama Miyazaki Tanaka Ohnishi