C-17 bicyclic amines of triterpenoids with HIV maturation inhibitory activity
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 bicyclic amines of triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III:These compounds are useful for the treatment of HIV and AIDS.
Bristol-Myers Squibb Company
A C C C C C C C C
A61P C07D C07D C07J C07D C07D C07D C07D C07D
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Zheng Sing-Yuen Nicholas A. Jie Yan Jacob Alicia Ny
Liu Sit Meanwell Chen Chen Swidorski Regueiro-Ren Sin