Substituted benzamides and substituted pyridinecarboxamides as Btk inhibitors
The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds in the treatment of Btk mediated disorders.
MERCK SHARP & DOHME CORP.
C C C C A C A A A Y A A A A A A C
C07D C07D C07D C07D A61K C07D A61K A61P A61P Y02A A61K A61P A61K A61K A61K A61K C07D
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Ying-Duo Joseph A. Shilan Hongjian Wensheng Chundao Sobhana Babu Ronald M. Xiaolei Rajan Hao Oleg B. Younong Deodialsingh Jian
Gao Kozlowski Liu Wang Yu Yang Boga Kim Gao Anand Wu Selyutin Yu Guiadeen Liu