Birch, Stewart, Kolasch & Birch, LLP
Donepezil derivative and use thereof
The present invention relates to a donepezil derivative of general formula (I) or a pharmaceutically acceptable salt thereof, wherein R in the formula is as disclosed herein; and a method for preparation thereof; and a composition comprising an effective amount of a compound of the general formula (I) or a pharmaceutically acceptable salt thereof. The present invention also relates to use of a compound of the general formula (I) or a pharmaceutically acceptable salt thereof in preparing a medicament for treating a disease resulted from an abnormality in acetylcholinesterase activity.
NORATECH PHARMACEUTICALS, INC.
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A61K C07D A61K A61K A61P A61K A61K A61K A61K A61K A61K
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Wei Chenggang Lulu Fei Cuixia Chunyan Pan
Wang Lin Wang Liu Zhang Zhou Chen