Heterocyclic GPR40 modulators
The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I:where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.
Amgen Inc.
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C07D C07D C07D A61P A61P A61P C07D A61P C07D A61P
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Yingcai SuJen Todd J. Julio C. Wang Paul Hilary Jinqian Rajiv Zice Zhongyu Michael J. Marc Jonathan B. XianYun Jiwen Zhihua
Wang Lai Kohn Medina Shen Dransfield Beck Liu Sharma Fu Wang Schmitt Vimolratana Houze Jiao Liu Ma