Cooley LLP
Salt form of a human histone methyltransferase EZH2 inhibitor
Provided herein is N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl (tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4′-(morpholinomethyl)-[1,1′-biphenyl]-3-carboxamide hydrobromide. Also provided herein is a particular polymorph form of this compound.
Eisai R&D Management Co., Ltd. Epizyme, Inc.
C A C Y A
C07D A61P C07D Y02A A61K
inventional inventional inventional additional inventional
Steven Francis Kristen Kuan-Chun Arani Kevin Wayne Hyeong Wook
Mathieu Fang Sanders Huang Chanda Kuntz Choi