Woodcock Washburn LLP
Triaryl compounds and derivates thereof
The present invention relates to compounds having the general formula (I) with the definitions of X, Y, R1, R2, R3, R4, R9, R10 given below, and solvates, hydrates, esters, and pharmaceutically acceptable salts thereof.Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of γ-secretase activity.
Ortho-McNeil Pharmaceutical, Inc.
A C C C A C A C C C C
A61P C07C C07D C07C A61P C07C A61P C07C C07C C07C C07C
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Svenja Valerie Chih Yung Cyrille Mihiro Kathryn Andrew Richard John Jeremy Yan Alison Remedios Jess Francis Adeline
Burckhardt Reader Ho Boussard Sunose Smelt Cansfield Harrison Major Zhang Reid Hernandez-Perni Taylor Wilson LeFormal