Cushman, Darby & Cushman
Process for the preparation of .sup.13 C-labelled compounds
 A process for preparing a .sup.13 C-labelled compound which comprises reacting an alcohol .sup.13 C-labelled carbon source compound and a substrate in the presence of an enzyme system consisting of oxidase belonging to EC1 group and capable of converting the alcohol .sup.13 C-labelled carbon source compound to an aldehyde .sup.13 C-labelled carbon source compound, lyase belonging to EC4 group and capable of synthesizing a carbon-carbon bond and at least one of isomerases belonging to EC5 group and capable of isomerizing substrates to obtain a .sup.13 C-labelled compound specifically labelled with .sup.13 C in a specific carbon position. 
Tokyo Gas. Co., Ltd.
C C C
C12P C12N C12P
inventional inventional inventional
Kunihiko Yoshiyuki Nobuo
Shibata Sato Kato