Modulators of ATP-binding cassette transporters
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Vertex Pharmaceuticals Incorporated
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Jason Mark Peter D. J. Sara S. Jinglan Brian Matthew
McCartney Miller Grootenhuis Hadida Ruah Zhou Bear Hamilton