WPAT, P.C.
Peptide compounds for inhibitions of platelet aggregation
The invention relates to a peptide compound and its pharmaceutical composition for inhibiting platelet aggregation and preventing/treating thrombogenic diseases. The invention develops pentapeptides and hexapeptides derived from snake venom C-type lectin-like proteins (CLPs) fragments, which can inhibit platelet aggregation and have antithrombotic activity without hemorrhagic tendency. Accordingly, they can be used as potential agents for the prevention and therapy of thrombogenic diseases.
NATIONAL TAIWAN UNIVERSITY
A A C A C A A A C A C C
A61K A61L C07K A61L C07K A61K A61K A61P C07K A61K C07K C07K
additional additional inventional inventional additional inventional inventional inventional inventional inventional inventional inventional
Tur-Fu Ching-Hu Chien-Hsin
Huang Chung Chang