Welsh & Katz, Ltd.
Multiplex method for nucleic acid detection
Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of predetermined nucleic acid target sequences using a multiplex assay format. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, genotyping, medical marker diagnostics, and the like.
Promega Corporation
C C Y C C C
C12Q C12Q Y10T C12Q C12Q C12Q
inventional inventional additional inventional inventional inventional
Roy James Robert Keith V. Martin K. Michelle Daniel John William Donna Christine Ann Trent Richard Byron
Welch Hartnett Wood Lewis Mandrekar Kephart Shultz Leippe Andrews Gu Rhodes