Lyon & Lyon LLP
Methods and compositions for inhibiting cell proliferative disorders
 The present invention concerns compounds and their use to inhibit the activity of a receptor tyrosine kinase. The invention is preferably used to treat cell proliferative disorders such as cancers charcterized by over-activity or inappropriate activity HER2 or EGFR. 
Sugen, Inc. Yissum Research and Development Company of the Hebrew University of Jerusalem
C C A C C C A A C C A C A A C C A
C07C C07C A61K C07D C07C C07C A61K A61K C07C C07C A61K C07C A61K A61K C07C C07C A61K
inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional inventional
Aviv Jianming Peng Cho Hui Elaina Klaus Peter Laura K. Alexander
Gazit Tsai Tang Chen Mann Hirth Shawver Levitzki