Imidazole derivatives as protective agents in reperfusion injury and severe inflammatory responses
 Compounds of the formula ##STR1## wherein the substituents are as defined in the disclosure. The compounds are particularly useful for inhibiting damage to a variety of mammalian tissue that are jeopardized, for example, during runaway inflammatory conditions due to the damaging presence of singlet oxygen, the hydroxyl radical, cytokines and growth factors. The compounds are also useful in inhibiting damage to cardiac and central nervous system tissues during reperfusion. 
Cytos Pharmaceuticals LLC
C C
C07D C07D
inventional inventional
Stanley Jack R.
Burt Collins