Pennie & Edmonds
Methods for producing enhanced antigenic shigella bacteria and vaccines comprising same
 Methods using in vitro processes are disclosed for inducing or enhancing expression of enteric bacterial antigens or virulence factors. The methods, therefore, produce antigenically enhanced enteric bacteria. Also methods for using the antigenically enhanced bacteria are also disclosed, as well as vaccines containing the enteric bacteria. Specifically, a whole enteric bacteria or components thereof are provided by Shigella species. Also there are other enteric bacteria which are useful for the disclosed invention; such as bacterial species and strains belonging to the genera Helicobacter and Campylobacter. 
Antex Biologics, Inc.
Y G C C C C G Y A A G G C A A Y G Y
Y10S G01N C12Q C12N C12R C12Q G01N Y10S A61K A61K G01N G01N C12N A61K A61P Y02A G01N Y10S
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Richard Ives John Lee Steven Michael
Walker Pace Frey