1,2,5-substituted benzimidazoles as FLAP modulators
The present invention relates to compounds of Formula (I),and solvates, hydrates, and pharmaceutically acceptable salts thereof, wherein ring A, R1, R5 and R6 are as defined herein, useful as FLAP modulators. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.
JANSSEN PHARMACEUTICA NV
A A C A C A C A A C A C C
A61K A61K C07D A61P C07D A61K C07D A61P A61K C07D A61K C07D C07D
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Wenying Wendy Alec D. Charlotte Virginia M. James P. Steven D. Paul J. Jing Kyle T. Curt A.
Chai Eccles Lebsack Deckhut Tanis Edwards Goldberg Krawczuk Liu Tarantino Dvorak