Leydig, Voit & Mayer, Ltd.
Method of expressing an exogenous nucleic acid
 The present invention provides a method of expressing an exogenous nucleic acid in a mammal. The method comprises non-systemically administering to a non-neuronal tissue of said mammal an exogenous nucleic acid operatively linked to a promoter. The exogenous nucleic acid is proximal to at least one native parvoviral inverted terminal repeat and does not require encapsidation. The expression of the exogenous nucleic acid in the tissue is not substantially diminished at 28 days after administration of the exogenous nucleic acid. 
Cornell Research Foundation, Inc.
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Todd K. Xiaohuai Neil R. Ronald G.
Rosengart Zhou Hackett Crystal