Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
Certain novel N-acylated spiropiperidine derivatives are ligands of the human melanocortin receptor(s) and, in particular, are selective ligands of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of MC-4R, such as obesity, diabetes, nicotine addiction, alcoholism, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.
Merck Sharp & Dohme Corp
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C07D A61P A61P A61P A61P A61P A61P
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Jian Ravi P. Tianying
Liu Nargund Jian