ERK inhibitors
The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are ERK2 inhibitors. The invention also provides a method of inhibiting ERK2 in a patient in need of such treatment comprising administering to said patient an effective amount of at least one compound of Formula (I). The invention also provides a method for treating cancer in a patient in need of such treatment, said method comprising administering to said patient an effective amount of at least one compound of Formula (I).
MSD R&D (CHINA) CO., LTD MERCK SHARP & DOHME CORP.
A C C A C A
A61K C07D C07D A61P C07D A61K
inventional inventional inventional inventional inventional inventional
Jianmin Xianhai Umar Faruk Ziping David Joseph Zhilong Phieng Wei Yimin David L.
Fu Huang Mansoor Liu Witter Kozlowski Wan Siliphaivanh Liu Qian Sloman