Foley & Lardner
Rho target protein Rho-kinase
 The object of the present invention is to provide a target protein for the activated Rho protein. The present invention is a protein having activated Rho protein binding activity and protein kinase activity or derivatives thereof. The molecular weight of the protein derived from bovine is about 164 kDa as measured by SDS-PAGE. The protein kinase activity of this protein is enhanced when it binds to the activated Rho protein. 
Kirin Beer Kabushiki Kaisha
A C C
A61K C12N C07K
additional inventional inventional
Akihiro Kozo Masaaki Takeshi Nobuaki
Iwamatsu Kaibuchi Ito Nakano Takahashi