Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
Compositions of kinase inhibitors and their use for treatment of cancer and other diseases related to kinases
The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases; to methods of inhibiting cancer stem cells by using a kinase inhibitor; to pharmaceutical compositions containing such compounds; and to methods of using such compounds in the treatment of a protein kinase related disorder in a mammal; and to processes of making such compounds and intermediates thereof.
Boston Biomedical, Inc.
A A C A A A A A A A A C A A A A A A A A A A A A A
A61K A61K C07D A61P A61P A61P A61P A61P A61P A61P A61P C07D A61P A61P A61P A61K A61P A61P A61P A61P A61P A61P A61K A61P A61P
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Harry Ji-Feng Youzhi Wei Chiang Jia
Rogoff Liu Li Li Li